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| Status |
Public on Nov 12, 2008 |
| Title |
TNFa-stimulation of XIAP -/- MEF |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
XIAP (X chromosome-linked inhibitor of apoptosis; ILP, BIRC4) is involved not only in apoptosis, but also in signal tranduction in the NF-kappaB, TGF-beta, bone morphogenic protein, and JNK signalling pathways. We have analyzed whether XIAP deletion leads to changes in gene expression, particularly after inflammatory stimulation.
Keywords: genetic modification, inflammatory response
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| Overall design |
Fibroblasts from wild-type and XIAP knockout mice were analyzed with and without TNFa stimulation (4 hours) using Affymetrix U74Av2 arrays.
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| Contributor(s) |
Winsauer G, Hofer-Warbinek R, Bilban M, de Martin R |
| Citation(s) |
18761086 |
| |
| Submission date |
Nov 30, 2005 |
| Last update date |
Feb 18, 2018 |
| Contact name |
Rainer de Martin |
| E-mail(s) |
rainer.demartin@meduniwien.ac.at
|
| Phone |
+431-40160-33161
|
| Organization name |
Medical University of Vienna
|
| Department |
Vascular Biology
|
| Street address |
Schwarzspanierstr. 17
|
| City |
Vienna |
| ZIP/Postal code |
A-1090 |
| Country |
Austria |
| |
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| Platforms (1) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA93851 |
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