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Series GSE37107 Query DataSets for GSE37107
Status Public on Sep 10, 2019
Title Genome-wide transcription analysis of whole blood prior to rituximab treatment in relation to clinical response
Organism Homo sapiens
Experiment type Expression profiling by array
Summary B cell depletion therapy is efficacious in RA patients failing on TNF blocking agents. However, approximately 40-50% of the rituximab-treated RA patients have a poor response. We investigated wheter baseline gene expression levels can discriminate between clinical nonresponders and responders to rituximab
 
Overall design Whole blood total RNA is isolated from PAXgene tubes obtained prior to start of rituximab treatment
 
Contributor(s) Verweij CL, Vosslamber S
Citation(s) 22540992
Submission date Apr 09, 2012
Last update date Sep 10, 2019
Contact name Saskia Vosslamber
E-mail(s) s.vosslamber@vumc.nl
Organization name VU University medical center
Street address de Boelelaan 1118
City Amsterdam
ZIP/Postal code 1081 HV
Country Netherlands
 
Platforms (1)
GPL6947 Illumina HumanHT-12 V3.0 expression beadchip
Samples (14)
GSM910736 whole blood rituximab treated baseline sample4 non-responder
GSM910737 whole blood rituximab treated baseline sample7 responder
GSM910738 whole blood rituximab treated baseline sample10 non-responder
Relations
BioProject PRJNA158433

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE37107_RAW.tar 6.2 Mb (http)(custom) TAR
GSE37107_non-normalized.txt.gz 4.5 Mb (ftp)(http) TXT
Processed data included within Sample table
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