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| Status |
Public on Dec 22, 2005 |
| Title |
Gene expression profiling in colonic adenoma and carcinoma in situ |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The majority of colon carcinomas are known to develop in tubular adenomas through multi-stage carcinogenesis. Recently, we have reported a simple and reproducible method for the expression profiling using microdissected cells from formalin-fixed tissue samples (Lee et al, World J Gastroenterol, 11:1937-1945, 2005). Using the method, we analyzed the expression profiling in colon tubular adenoma/carcinoma sequence. Epithelial cells of carcinoma, tubular adenoma, and normal colon mucosa were microdissected from colon tubular adenomas containing focal adenocarcinomas.
Keywords: disease (colon cancer) state analysis
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| |
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| Overall design |
Microarray (GenePlorer TwinChip Human-8K) hybridizations were duplicated for adenomas, and carcinoma.
normal vs adenoma :4 array repeated
normal vs carcinoma : 4 array repeated
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| |
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| Contributor(s) |
Lee I, Bang S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 20, 2005 |
| Last update date |
Jan 18, 2013 |
| Contact name |
Inchul Lee |
| E-mail(s) |
iclee@amc.seoul.kr
|
| Phone |
82-2-3010-4167
|
| URL |
http://iclee.amc.seoul.kr
|
| Organization name |
University of Ulsan College of Medicine
|
| Department |
Pathology
|
| Lab |
Disease Genomic Research Lab.
|
| Street address |
388-1 Poongnap-Dong, Songpa-Gu
|
| City |
Seoul |
| ZIP/Postal code |
138-736 |
| Country |
South Korea |
| |
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| Platforms (1) |
| GPL1818 |
GenePlorer™ TwinChip™ Human-8K |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA94121 |
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