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Status |
Public on Jan 01, 2007 |
Title |
Transcriptomics in cardiac surgery |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Anesthetic gases elicit organ protection in patients undergoing coronary artery bypass graft (CABG) surgery. This study aimed at identifying myocardial transcriptional phenotypes and anesthetic-induced changes in gene expression to predict cardiovascular biomarkers and cardiac function after off-pump CABG. Keywords: cardiac surgery, anesthetics
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Overall design |
Patients scheduled for off-pump CABG were randomized into a group with the anesthetic gas sevoflurane (n=10) or the intravenous anesthetic propofol (n=10). Atrial samples were collected at the beginning and end of bypass surgery to determine gene expression profiles.
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Contributor(s) |
Lucchinetti E, Zaugg M |
Citation(s) |
17325502 |
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Submission date |
Mar 07, 2006 |
Last update date |
Mar 25, 2019 |
Contact name |
Michael Zaugg |
E-mail(s) |
michael.zaugg@usz.ch
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Phone |
+41-1-255 11 11
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Organization name |
Anesthesiology, University Hospital Zurich
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Department |
Anesthesiology
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Lab |
Perioperative Cardioprotection Research Group
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Street address |
Raemistrasse 100
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City |
Zurich |
ZIP/Postal code |
8091 |
Country |
Switzerland |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (40)
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Relations |
BioProject |
PRJNA94569 |