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| Status |
Public on Nov 30, 2015 |
| Title |
Gfi1 proteins regulate the emergence of HSCs and blood precursors in the AGM through recruitment of LSD1 [Affymetrix] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptome analysis of sorted hemogenic endothelial cells with and without Lsd1 inhibition with 300nM of compound B.
Transcriptome analysis to detect the global changes in gene expression upon LSD1 inhibition.
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| Overall design |
Bry-GFP ES line derived FLK1+ mesodermal were differentiated to Cdh5/CD41 positive HE cells with/out the compound B. CD41 compartment of both populations were FACS sorted and processed for Affymetrix.
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| Contributor(s) |
Thambyrajah RS, Mazan M, Patel R, Moignard V, Stefanska M, Clapes T, Möröy T, Robin C, Cowley S, Göttgens B, Kouskoff V, Lacaud G |
| Citation(s) |
26619147 |
| |
| Submission date |
Apr 30, 2014 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Roshana S Thambyrajah |
| E-mail(s) |
Roshana.Thambyrajah@cruk.manchester.ac.uk
|
| Organization name |
CRUK Manchester
|
| Department |
Stem Cell Biology
|
| Street address |
Wilmslow Road
|
| City |
Manchester |
| ZIP/Postal code |
M20 4BX |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL6193 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [probe set (exon) version] |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE57251 |
Gfi1 proteins regulate the emergence of HSCs and blood precursors in the AGM through recruitment of LSD1 |
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| Relations |
| BioProject |
PRJNA246691 |
