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| Status |
Public on Oct 17, 2014 |
| Title |
Expression data from HUVEC with YAP siRNA knockdown |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
YAP knockdown in HUVEC elicits proliferation and cell cycle preogression defects. YAP deficient cells caused arrest in G1 and defects in S-phase entry. The microarray analysis was conducted to identify potential YAP targets that are involved in HUVEC cell cycle regulation
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| Overall design |
mRNA samples were collected from siRNA treated HUVECs 30 hour after transfection. Four biological replicates were used for each condition: control (RISC-free) and knockdown (siYAP#1 and siYAP#2)
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| Contributor(s) |
Shen Z, Stanger BZ |
| Citation(s) |
25635998 |
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| Submission date |
Oct 02, 2014 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Zhewei Shen |
| Organization name |
University of Pennsylvania
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| Lab |
Ben Stanger, M.D., Ph.D.
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| Street address |
BRB II/III Rm 527, 421 Curie Blvd.,
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| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| GSM1517967 |
RISC-free control transfected, biological rep 1 |
| GSM1517968 |
RISC-free control transfected, biological rep 2 |
| GSM1517969 |
RISC-free control transfected, biological rep 3 |
| GSM1517970 |
RISC-free control transfected, biological rep 4 |
| GSM1517971 |
siYAP RNA #1 transfected, biological rep 1 |
| GSM1517972 |
siYAP RNA #1 transfected, biological rep 2 |
| GSM1517973 |
siYAP RNA #1 transfected, biological rep 3 |
| GSM1517974 |
siYAP RNA #1 transfected, biological rep 4 |
| GSM1517975 |
siYAP RNA #2 transfected, biological rep 1 |
| GSM1517976 |
siYAP RNA #2 transfected, biological rep 2 |
| GSM1517977 |
siYAP RNA #2 transfected, biological rep 3 |
| GSM1517978 |
siYAP RNA #2 transfected, biological rep 4 |
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| Relations |
| BioProject |
PRJNA262898 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE61989_RAW.tar |
52.3 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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