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| Status |
Public on Jan 15, 2015 |
| Title |
Discovered salivary transcriptomic biomarkers for the detection of gastric cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We have performed gene expression microarray analysis to profile transcriptomic signatures between cancer and noncancerous patients
Gastric cancer is currently the second leading cause of cancer deaths. Due to the difficulty of diagnosing patients in the early stages of gastric cancer, it is critical to develop a method that can diagnose the disease at the early stage to allow for better treatment options. In this study, we discovered salivary transcriptomic and miRNA biomarkers for the detection of gastric cancer and identified there are mRNA-miRNA correlations in saliva.
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| Overall design |
RNA was extracted from saliva supernatant and mRNA candidates were identified that can distinguish gastric cancer from non-gastric cancer patients
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| Contributor(s) |
Yoshizawa JM, Wang X, Elashoff DE, Zhou H, Kim Y, Kim S, Wong DT |
| Citation(s) |
30097497 |
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Yoshizawa JM, Wang X, Elashoff David, Zhou H, Kim Y, Kim S and Wong David. Salivary Biomarkers for Gastric Cancer Detection: The Saliva RNA Interactome. Conference: AADR Annual Meeting 2012.
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| Submission date |
Jan 14, 2015 |
| Last update date |
Dec 15, 2020 |
| Contact name |
David Wong |
| Organization name |
UCLA
|
| Department |
Dentistry
|
| Street address |
10833 Le Conte Ave
|
| City |
Los Angeles |
| ZIP/Postal code |
90095 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (94)
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| Relations |
| BioProject |
PRJNA272615 |
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