|
| Status |
Public on Dec 28, 2016 |
| Title |
SOX9 Drives WNT Pathway Activation in Prostate Cancer [ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
SOX9 is critical for prostate development and is implicated in prostate cancer, we used SOX9 ChIP-seq in combination with transcriptome profiling to identify genes and pathways it regulates in normal or neoplastic epithelium.
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| |
|
| Overall design |
Chromatin was immunoprecipitated by SOX9 antibody in the TMPRSS2-ERG fusion positive prostate cancer cell line VCaP with high basal SOX9 expression and submitted for high throughput sequencing in parallel with input control.
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| |
|
| Contributor(s) |
Ma F, Yuan X, Balk SP |
| Citation(s) |
27043282 |
| |
| Submission date |
Dec 31, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Fen Ma |
| E-mail(s) |
fenmag@gmail.com
|
| Organization name |
BIDMC
|
| Department |
Hem/Onc
|
| Lab |
Balk lab
|
| Street address |
3 Blackfan Circle
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (2) |
|
| This SubSeries is part of SuperSeries: |
| GSE76452 |
SOX9 Drives WNT Pathway Activation in Prostate Cancer |
|
| Relations |
| BioProject |
PRJNA307344 |
| SRA |
SRP067970 |
