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Status |
Public on Jan 26, 2016 |
Title |
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia [HTA-2_0] |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We screened TKI-treated-CML-samples in different-phases based on < or >10% copies of BCR-ABL, undetected and control-samples for generating transcriptomics-profile. Transcriptionally, three clusters were identified which showed correlation with BCR-ABL transcript-levels i.e. <10% copies (I-cluster) , undetectable (II-cluster) and >10% copies (III-cluster).
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Overall design |
CML-new cases as well as Tyrosine kinase treated-different phases of CML
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Contributor(s) |
Singh N, Kumar Tripathi A, Kumar Sahu D, Mishra A, Chowdhry R, Kant R |
Citation missing |
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Submission date |
Jan 25, 2016 |
Last update date |
Oct 29, 2018 |
Contact name |
Neetu Singh |
E-mail(s) |
neetuaashi@yahoo.com
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Phone |
9984801444
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Organization name |
King George's Medical University
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Department |
Center for Advance Research
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Street address |
Chowk
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City |
Lucknow |
ZIP/Postal code |
226003 |
Country |
India |
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Platforms (1) |
GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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Samples (40)
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This SubSeries is part of SuperSeries: |
GSE77573 |
Combination of multiomics approach and BCR-ABL based molecular testing: A better way to monitor treatment regimen and disease progression in Chronic Myeloid Leukemia |
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Relations |
BioProject |
PRJNA309679 |