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Status |
Public on Mar 09, 2017 |
Title |
Genome-wide changes in H3K4me3 after MEN1 silencing in MCF-7 cells |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
We performed ChIP-seq using H3K4me3 antibodies in MCF-7 cells after induction of small hairpin RNA's directed at the MEN1 mRNA or a control sequence. We demonstrate that at a selected group of loci H3K4me3 is affected by MEN1 silencing.
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Overall design |
Comparison of genome-wide H3K4me3 binding after ShMEN1 induction vs ShCtrl, in duplicate.
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Contributor(s) |
Dreijerink KM, Groner AC |
Citation(s) |
28273452 |
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Submission date |
Aug 08, 2016 |
Last update date |
May 15, 2019 |
Contact name |
Koen M.A. Dreijerink |
E-mail(s) |
koendreijerink@yahoo.com
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Organization name |
Dana-Farber Cancer Institute
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Department |
Medical Oncology
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Street address |
450 Brookline Avenue
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City |
Boston |
State/province |
MA |
ZIP/Postal code |
02215 |
Country |
USA |
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Platforms (2) |
GPL15520 |
Illumina MiSeq (Homo sapiens) |
GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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Samples (6)
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Relations |
BioProject |
PRJNA338157 |
SRA |
SRP081088 |