|
| Status |
Public on Jun 12, 2017 |
| Title |
Transcriptional profile Lactobacillus plantarum WCFS1 : olive oil (OO) treated cells |
| Platform organism |
Lactiplantibacillus plantarum WCFS1 |
| Sample organism |
Lactiplantibacillus plantarum |
| Experiment type |
Expression profiling by array
|
| Summary |
Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with olive oil (OO). Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcriptional profile reveals the downregulation of processes associated with rapid growth and the induction of stress-related pathways indicating the involvement of the stringent response. The fatty acid biosynthetic pathway is thoroughly downregulated at the transcriptional level and genes involved in host-cell signalling are differentially regulated.
|
| |
|
| Overall design |
Biological triplicates: untreated cells: Control vs. Olive oil treated cells: Experimental
|
| |
|
| Contributor(s) |
del Mar Esteban-Torres M, Reverón I, Plaza L, de las Rivas B, Muñoz R, López de Felipe F |
| Citation(s) |
28261192 |
| |
| Submission date |
Nov 04, 2016 |
| Last update date |
Jun 12, 2017 |
| Contact name |
Felix Lopez de Felipe |
| E-mail(s) |
fxlopez@ictan.csic.es
|
| Organization name |
ICTAN-CSIC
|
| Street address |
Jose Antonio Novais
|
| City |
Madrid |
| ZIP/Postal code |
28040 |
| Country |
Spain |
| |
|
| Platforms (1) |
| GPL15934 |
Agilent-026636 Prueba Lp IFI 021109 |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA352480 |
