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| Status |
Public on Jan 15, 2017 |
| Title |
RNA Sequencing Reveals Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Splenocytes were FACS-sorted from Wild-type and Mir146a-/- mice to isolate specific B-cell developmental stages. Utilizing high-throughput sequencing, we comparatively analyzed developmental stage-specific splenic B cell transcriptomes, including Transitional-1 (T1), Transitional-2 (T2), Marginal zone (MZ) and Follicular (FO) in both Wild-type and Mir146a-/- B cells. Two replicates of each developmental stage were submitted for high-throughput sequencing.
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| |
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| Overall design |
Transcriptomic profiles of primary B cell developmental subsets (T1, T2 MZ, FO) from Wild-type and Mir146a-/- mice in duplicate.
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| |
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| Contributor(s) |
Rao D, King J |
| Citation(s) |
28138326 |
| |
| Submission date |
Jan 06, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
matteo pellegrini |
| E-mail(s) |
matteop@mcdb.ucla.edu
|
| Phone |
310 825-0012
|
| Organization name |
UCLA
|
| Street address |
610 charles young drive east
|
| City |
los angeles |
| State/province |
CA |
| ZIP/Postal code |
90095 |
| Country |
USA |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA360425 |
| SRA |
SRP096191 |
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