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| Status |
Public on Aug 29, 2008 |
| Title |
SAOS-2 cells, RBP2 knockdown or pRB overexpression |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
RBP2 is downstream of pRB pathway
We used gene expression profiling experiments to investigate if gene expression changes in cells with RBP2 knockdown significantly overlap with gene expression changes in cells overexpressing pRB, consistent with the data that knockdown of RBP2 phenocopies reintroduction of pRB in SAOS-2 (RB-/-) cells
Keywords: epistatic experiment
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| Overall design |
Knockdown of RBP2 by siRNA to RBP2 (RBP2siRNA) in SAOS-2 (RB-/-) cells in comparison to overexpression of pRB in the SOAS-2 (RB-/-) cells and scrambled version of the RBP2 siRNA (RBP2scsiRNA)
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| |
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| Contributor(s) |
Benevolenskaya EV, Kaelin WG |
| Citation(s) |
18722178 |
| |
| Submission date |
Nov 26, 2007 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Elizaveta V Benevolenskaya |
| E-mail(s) |
evb@uic.edu
|
| Phone |
312-413-8947
|
| Organization name |
University of Illinois at Chicago
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| Department |
Biochemistry and Molecular Genetics
|
| Street address |
900 S. Ashland Ave.
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60607 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA103587 |
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