|
| Status |
Public on Jun 28, 2017 |
| Title |
Identification and mode of action of a plant natural product targeting human fungal pathogens |
| Organism |
Candida albicans |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Candida albicans was subjected to treatment with tomatidine and samples were taken at 2 different time points (1h, 3h). The results show that tomatidine induces genes involved in ergosterol biosynthesis as compared to untreated controls.
|
| |
|
| Overall design |
C. albicans SC5314 strain was exposed to 250 µM tomatidine and total RNA was extracted after 1 h or 3 h tomatidine/solvent exposure.
|
| |
|
| Contributor(s) |
Dorsaz S, Sanglard D |
| Citation(s) |
28674054 |
| |
| Submission date |
Mar 23, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Dominique Sanglard |
| E-mail(s) |
Dominique.Sanglard@chuv.ch
|
| URL |
http://www.chuv.ch/imul
|
| Organization name |
University of Lausanne and University Hospital Center
|
| Street address |
Rue Bugnon 48
|
| City |
Lausanne |
| ZIP/Postal code |
1011 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL19036 |
Illumina HiSeq 2500 (Candida albicans) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA380235 |
| SRA |
SRP102364 |
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