|
| Status |
Public on Jan 31, 2019 |
| Title |
DLPFC_Alzheimer_Br5081 |
| Sample type |
genomic |
| |
|
| Source name |
DLPFC
|
| Organism |
Homo sapiens |
| Characteristics |
sample_plate: Plate 4
sentrix_position: R05C02
brnum: Br5081
brnum: brain
tissue region: DLPFC
disease state (dx): Alzheimer
age: 59
Sex: F
race: CAUC
negcontrol_pc1: 2.50330128221957
negcontrol_pc2: -1.27530259119115
neun_pos: 0.0738689048715952
snppc1: -0.0541186
|
| Extracted molecule |
genomic DNA |
| Extraction protocol |
Following manufacturer's protocol
|
| Label |
Cy3/Cy5
|
| Label protocol |
Following manufacturer's protocol
|
| |
|
| Hybridization protocol |
Following manufacturer's protocol
|
| Scan protocol |
Following manufacturer's protocol
|
| Description |
Postmortem human brain tissue samples from four brain regions in an Alzheimers disease case-control series used to generate Human450k DNA methylation data.
4-C08
|
| Data processing |
idat files were imported with minfi then stratified quantile normalized in minfi.
[matrix_processed.csv] Stratified quantile normalized beta values for tested probes (see publication).
[matrix_signal_intensities.csv] Unmethylated and methylated signal intensities
|
| |
|
| Submission date |
Jan 30, 2019 |
| Last update date |
Jan 31, 2019 |
| Contact name |
Stephen A Semick |
| Organization name |
University of Maryland School of Medicine
|
| Street address |
655 W Baltimore St S
|
| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21201 |
| Country |
USA |
| |
|
| Platform ID |
GPL13534 |
| Series (1) |
| GSE125895 |
Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease |
|
