|
Status |
Public on Jun 23, 2010 |
Title |
pCR breast biopsy, sample 16 rep 1 |
Sample type |
RNA |
|
|
Source name |
breast needle biopsy, pretreatment, sample 16 rep 1
|
Organism |
Homo sapiens |
Characteristics |
pathological complete response: yes tissue: Breast tumor biopsy
|
Treatment protocol |
all samples are from pretreatment patients
|
Growth protocol |
all samples are from frozen primary breast needle biopsies
|
Extracted molecule |
total RNA |
Extraction protocol |
frozen biopsies were sectioned, laser capture microdissected for invasive tumor cells, and total RNA was isolated according to the manufacturer's instructions.
|
Label |
biotin
|
Label protocol |
standard Affymetrix protocol
|
|
|
Hybridization protocol |
standard Affymetrix protocol
|
Scan protocol |
standard Affymetrix protocol
|
Description |
Gene expression data from pretreatment breast needle biopsies
|
Data processing |
The data were analyzed for differentially expressed probes between responder and non-responder patient tumor samples. Data was RMA summarized, quantile normalized and baseline transformed to the median of all samples using GeneSpring GX Software (Agilent).
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|
|
Submission date |
Jun 22, 2010 |
Last update date |
Jun 22, 2010 |
Contact name |
Jennifer Pietenpol |
E-mail(s) |
j.pietenpol@vanderbilt.edu
|
Organization name |
Vanderbilt University Medical Center
|
Street address |
652 Preston Research Building, 23rd Avenue South at Pierce
|
City |
Nashville |
State/province |
TN |
ZIP/Postal code |
37232 |
Country |
USA |
|
|
Platform ID |
GPL570 |
Series (1) |
GSE22513 |
Markers of Taxane Sensitivity in Breast Cancer |
|