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GTR Home > Conditions/Phenotypes > Oocyte maturation defect 10

Oocyte maturation defect 10

Synonyms
OOCYTE/ZYGOTE/EMBRYO MATURATION ARREST 10

Summary

Oocyte/zygote/embryo maturation arrest-10 (OZEMA10) is characterized by high rates of abnormal fertilization of mature oocytes, with development of multiple pronuclei or absent pronucleus. Morphologically normal zygotes often undergo early embryonic arrest, and surviving embryos fail to establish a successful pregnancy after implantation (Wang et al., 2020). For a discussion of genetic heterogeneity of OZEMA, see 615774. [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: C15orf60, CT147, OOMD10, OZEMA10, REC114
    Summary: REC114 meiotic recombination protein

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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