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Oocyte maturation defect 11

Summary

Oocyte/zygote/embryo maturation arrest-11 (OZEMA11) is characterized by reduced or absent fertility and poor embryonic outcomes with assisted reproductive technology. Oocytes with multiple sperm heads and multiple pronuclei have been observed after overnight in vitro fertilization (Maddirevula et al., 2022). For a general phenotypic description and a discussion of genetic heterogeneity of OZEMA, see 615774. [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: OOMD11, OZEMA11, SAS1B, ASTL
    Summary: astacin like metalloendopeptidase

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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