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MGMT
Clinical Genetic Test
Help
offered by
Caris Life Sciences
GTR Test Accession: Help GTR000558479.1
CANCER
Last updated in GTR: 2017-11-07
View version history
Last annual review date for the lab: 2024-03-25 LinkOut
At a Glance
Test purpose: Help
Predictive
Conditions (1): Help
Neoplasm
Proteins (1): Help
MGMT
Methods (1): Help
Biochemical Genetics - Immunohistochemistry: IHC
Target population: Help
Not provided
Clinical validity: Help
Not provided
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
Caris Life Sciences
View lab's website
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Test Order Code, How to Order, Specimen source, Lab contact for this test, Contact policy, Test strategy, Test development
Conditions Help
Total conditions: 1
Condition/Phenotype Identifier
Test Targets
Proteins Help
Total proteins: 1
Protein Associated Condition
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument *
Immunohistochemistry
IHC
* Instrument: Not provided
Clinical Information
Test purpose: Help
Predictive
Recommended fields not provided:
Clinical validity, Clinical utility, Target population, What is the protocol for interpreting a variation as a VUS?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
The Caris MGMT IHC test has been validated with an overall 100% accuracy: 100% Accuracy for positive results (5/5) and 100% Accuracy of negative results (22/22). The results of all Precision studies show 100% concordance (24/24). Analytical Sensitivity was established at 100%: (5/5 cell line samples and 3/3 FFPE tissue … View more
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Alternative Assessment
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Not provided
Additional Information
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.