GTR Test Accession:
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GTR000593051.4
Last updated in GTR:
2023-08-16
View version history
GTR000593051.4,
last updated:
2023-08-16
GTR000593051.3,
last updated:
2022-08-25
GTR000593051.2,
last updated:
2022-01-27
GTR000593051.1,
registered in GTR:
2021-09-21
Last annual review date for the lab: 2024-08-23
LinkOut
At a Glance
Test purpose:
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Drug Response;
Monitoring;
Predictive; ...
Conditions (1):
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Drug metabolism or response
Genes (26):
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Methods (1):
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Molecular Genetics - Targeted variant analysis: SNP Detection
Target population: Help
Not provided
Clinical validity:
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Not provided
Clinical utility:
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Guidance for selecting a drug therapy and/or dose
Ordering Information
Offered by:
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Test short name:
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Snapshot PGx
Specimen Source:
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- Buccal swab
- Peripheral (whole) blood
- Saliva
Who can order: Help
- Genetic Counselor
- Health Care Provider
- Licensed Physician
- Nurse Practitioner
- Physician Assistant
Lab contact:
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David Finegold, MD, ABMGG Board Certified, ABP, Diplomate of the American Board of M, Lab Director
info@arielmedicine.com
(844) 692-7435
info@arielmedicine.com
(844) 692-7435
Contact Policy:
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Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order:
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1) Licensed clinician logs in to Ariel's secure portal via website
Order URL
Order URL
Test service:
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Clinical Testing/Confirmation of Mutations Identified Previously
Result interpretation
Result interpretation
Test development:
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Test developed by laboratory (no manufacturer test name)
Informed consent required:
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Yes
Pre-test genetic counseling required:
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Decline to answer
Post-test genetic counseling required:
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Decline to answer
Recommended fields not provided:
Test Order Code,
Test strategy
Conditions
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Total conditions: 1
| Condition/Phenotype | Identifier |
|---|
Test Targets
Genes
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Total genes: 26
| Gene | Associated Condition | Germline or Somatic | Allele (Lab-provided) | Variant in NCBI |
|---|
Methodology
Total methods: 1
Method Category
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Test method
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Instrument *
Targeted variant analysis
SNP Detection
* Instrument: Not provided
Clinical Information
Test purpose:
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Drug Response;
Monitoring;
Predictive;
Therapeutic management
Clinical utility:
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Guidance for selecting a drug therapy and/or dose
View citations (2)
- Antidepressant drugs affect dopamine uptake. Halaris AE, et al. Biochem Pharmacol. 1975;24(20):1896-7. doi:10.1016/0006-2952(75)90412-8. PMID: 19. Table of Pharmacogenomic Associations. U.S. Food and Drug Administration. https://www.fda.gov/medical-devices/precision-medicine/table-pharmacogenetic-associations. Accessed August 10, 2021..
- https://www.fda.gov/medical-devices/precision-medicine/table-pharmacogenetic-associations
Variant Interpretation:
Will the lab re-contact the ordering physician if variant interpretation changes?
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Yes.
Yes.
Research:
Is research allowed on the sample after clinical testing is complete?
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Yes, but patient must provide consent to enable such activities.
Yes, but patient must provide consent to enable such activities.
Recommended fields not provided:
Clinical validity,
Target population,
What is the protocol for interpreting a variation as a VUS?,
Are family members with defined clinical status recruited to assess significance of VUS without charge?,
Sample negative report,
Sample positive report
Technical Information
Test Confirmation:
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Confirmatory Sequencing
Availability:
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Tests performed
Interpretation performed in-house
Report generated in-house
Specimen preparation performed both in-house and at an outside lab
Wet lab work performed at an outside lab
Test performance comments
Wet lab work is performed at partner laboratory. All elements of test performance characteristics were performed at the outside laboratory. Interpretation and report generation is performed in-house.
Interpretation performed in-house
Report generated in-house
Specimen preparation performed both in-house and at an outside lab
Wet lab work performed at an outside lab
Test performance comments
Wet lab work is performed at partner laboratory. All elements of test performance characteristics were performed at the outside laboratory. Interpretation and report generation is performed in-house.
Analytical Validity:
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The test demonstrates >98% analytical sensitivity and specificity for the variants tested.
Proficiency testing (PT):
Is proficiency testing performed for this test?
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No
Method used for proficiency testing: Help
Intra-Laboratory
No
Method used for proficiency testing: Help
Intra-Laboratory
Recommended fields not provided:
Assay limitations,
Description of internal test validation method,
Citations for Analytical validity,
PT Provider,
Description of PT method,
Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review:
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Not provided
Additional Information
Reviews:
Clinical resources:
Consumer resources:
IMPORTANT NOTE:
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NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice.
Patients and consumers
with specific questions about a genetic test should contact a health care provider or a genetics professional.