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OnkoRisk Women's Hereditary Cancer Panel
Clinical Genetic Test
Help
offered by
BioReference Health
View lab's test page
LinkOut
GTR Test Accession: Help GTR000613041.1
CANCERINHERITED DISEASEDIGESTIVE SYSTEM ... View more
Registered in GTR: 2023-10-20
View version history
Last annual review date for the lab: 2024-01-12 LinkOut
At a Glance
Test purpose: Help
Diagnosis; Predictive; Risk Assessment
Conditions (34): Help
Solid tumor; Ataxia-telangiectasia syndrome; Breast adenocarcinoma more...
Genes (18): Help
ATM (11q22.3); BARD1 (2q35); BRCA1 (17q21.31); BRCA2 (13q13.1); BRIP1 (17q23.2) more...
Methods (1): Help
Molecular Genetics - Sequence analysis of the entire coding region: Next-Generation (NGS)/Massively parallel sequencing (MPS)
Target population: Help
Patients with a personal or family history of breast, ovarian, …
Clinical validity: Help
Clinical validity is dependent on individual patient clinical picture and …
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
BioReference Health
View lab's website
View lab's test page
Specimen Source: Help
Who can order: Help
  • Genetic Counselor
  • Health Care Provider
  • Licensed Physician
  • Nurse Practitioner
  • Physician Assistant
Test Order Code: Help
TP67
LOINC codes: Help
**LOINC codes notice
CPT codes: Help
**AMA CPT codes notice

Copyright: 2023 American Medical Association. All rights reserved.

Lab contact: Help
Sarah Witherington, MS, Certified Genetic counselor, CGC, Genetic Counselor
switherington@bioreference.com
224-250-3416
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
Post-test email/phone consultation regarding genetic test results and interpretation is provided to patients/families.
Pre-test email/phone consultation regarding genetic test results and interpretation is provided to patients/families.
Test service: Help
Genetic counseling
    OrderCode: TQ06, TQ07
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Based on applicable state law
Pre-test genetic counseling required: Help
No
Post-test genetic counseling required: Help
No
Recommended fields not provided:
How to Order, Test strategy
Conditions Help
Total conditions: 34
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 18
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument
Sequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Illumina NovaSeq
Clinical Information
Test purpose: Help
Diagnosis; Predictive; Risk Assessment
Clinical validity: Help
Clinical validity is dependent on individual patient clinical picture and family history of disease.
Target population: Help
Patients with a personal or family history of breast, ovarian, pancreatic, prostate, or colon cancer who wish to know their risk for developing a hereditary cancer. Based on ACOG recommendations.
Variant Interpretation:
Will the lab re-contact the ordering physician if variant interpretation changes? Help
Yes.
Recommended fields not provided:
Clinical utility, What is the protocol for interpreting a variation as a VUS?, Are family members with defined clinical status recruited to assess significance of VUS without charge?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
Limit of detection: 4% VAF for small variants. Analytical Sensitivity: 100% (for SNVs and Indels at 4% VAF and gene amplification) Analytical Specificity: > 98.3% for Indels. >99.8% for SNVs
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Internal and formal PT
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Not provided
NYS CLEP Approval: Help
Number:
Status: Pending
Additional Information
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.