U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Staphylococcal necrotizing pneumonia

MedGen UID:
1637863
Concept ID:
C4706659
Disease or Syndrome
Synonyms: Necrotizing pneumonia caused by Panton-Valentine leukocidin producing Staphylococcus aureus; staphylococcal necrotizing pneumonia
SNOMED CT: Staphylococcal necrotizing pneumonia (763888005); Necrotizing pneumonia caused by Panton-Valentine leukocidin producing Staphylococcus aureus (763888005)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018183
Orphanet: ORPHA36238

Definition

A rare bacterial pulmonary infectious disease caused by a Panton-Valentine leukocidin-producing Staphylococcus aureus strain, characterized by severe respiratory failure, extensive, rapidly progressing pneumonia and hemorrhagic lung necrosis. Patients typically present with influenza-like symptoms, such as fever, cough, and chest pain, as well as hemoptysis, hypotension, leukopenia, and severe respiratory symptoms that rapidly evolve to acute respiratory distress syndrome and septic shock. High mortality is associated. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStaphylococcal necrotizing pneumonia

Professional guidelines

PubMed

Gross CJ, Porter JJ, Lipsett SC, Monuteaux MC, Hirsch AW, Neuman MI
Hosp Pediatr 2021 Mar;11(3):207-214. Epub 2021 Feb 12 doi: 10.1542/hpeds.2020-001800. PMID: 33579749
David MZ, Daum RS
Curr Top Microbiol Immunol 2017;409:325-383. doi: 10.1007/82_2017_42. PMID: 28900682
Fartoukh M, Parrot A, Khalil A
Curr Opin Pulm Med 2008 May;14(3):195-202. doi: 10.1097/MCP.0b013e3282f79663. PMID: 18427242

Recent clinical studies

Etiology

Sicot N, Khanafer N, Meyssonnier V, Dumitrescu O, Tristan A, Bes M, Lina G, Vandenesch F, Vanhems P, Etienne J, Gillet Y
Clin Microbiol Infect 2013 Mar;19(3):E142-8. Epub 2012 Dec 12 doi: 10.1111/1469-0691.12022. PMID: 23237492

Prognosis

Sicot N, Khanafer N, Meyssonnier V, Dumitrescu O, Tristan A, Bes M, Lina G, Vandenesch F, Vanhems P, Etienne J, Gillet Y
Clin Microbiol Infect 2013 Mar;19(3):E142-8. Epub 2012 Dec 12 doi: 10.1111/1469-0691.12022. PMID: 23237492

Clinical prediction guides

Sicot N, Khanafer N, Meyssonnier V, Dumitrescu O, Tristan A, Bes M, Lina G, Vandenesch F, Vanhems P, Etienne J, Gillet Y
Clin Microbiol Infect 2013 Mar;19(3):E142-8. Epub 2012 Dec 12 doi: 10.1111/1469-0691.12022. PMID: 23237492

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...