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Disorder of lung

MedGen UID:
7399
•Concept ID:
C0024115
•
Disease or Syndrome
Synonym: Lung disorder
SNOMED CT: Disorder of lung (19829001); Lung disorder (19829001); Pulmonary disease (19829001)
 
Monarch Initiative: MONDO:0005275
Orphanet: ORPHA101944

Definition

A non-neoplastic or neoplastic disorder affecting the lung. Representative examples of non-neoplastic disorders include chronic obstructive pulmonary disease and pneumonia. Representative examples of neoplastic disorders include benign processes (e.g., respiratory papilloma) and malignant processes (e.g., lung carcinoma and metastatic cancer to the lung). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Therapeutic intervention: assessing the role of the international consensus guidelines.
Nathan SD
Chest 2005 Nov;128(5 Suppl 1):533S-539S. doi: 10.1378/chest.128.5_suppl_1.533S. PMID: 16304244

Recent clinical studies

Etiology

Sputum microbiota associated with new, recurrent and treatment failure tuberculosis.
Wu J, Liu W, He L, Huang F, Chen J, Cui P, Shen Y, Zhao J, Wang W, Zhang Y, Zhu M, Zhang W, Zhang Y
PLoS One 2013;8(12):e83445. Epub 2013 Dec 13 doi: 10.1371/journal.pone.0083445. PMID: 24349510Free PMC Article
Ultrastructural characterization of genetic diffuse lung diseases in infants and children: a cohort study and review.
Citti A, Peca D, Petrini S, Cutrera R, Biban P, Haass C, Boldrini R, Danhaive O
Ultrastruct Pathol 2013 Oct;37(5):356-65. doi: 10.3109/01913123.2013.811454. PMID: 24047351
From the archives of the AFIP: Lung disease in premature neonates: radiologic-pathologic correlation.
Agrons GA, Courtney SE, Stocker JT, Markowitz RI
Radiographics 2005 Jul-Aug;25(4):1047-73. doi: 10.1148/rg.254055019. PMID: 16009823

Diagnosis

Invasive mucinous adenocarcinoma of the lung arising in a type 1 congenital pulmonary airway malformation in a 68-year-old patient: a case report.
Frick AE, Decaluwé H, Weynand B, Proesmans M, Van Raemdonck D
Acta Chir Belg 2021 Feb;121(1):55-60. Epub 2019 Jul 2 doi: 10.1080/00015458.2019.1634926. PMID: 31262240
Ultrastructural characterization of genetic diffuse lung diseases in infants and children: a cohort study and review.
Citti A, Peca D, Petrini S, Cutrera R, Biban P, Haass C, Boldrini R, Danhaive O
Ultrastruct Pathol 2013 Oct;37(5):356-65. doi: 10.3109/01913123.2013.811454. PMID: 24047351
Melanoma-associated antigen expression in lymphangioleiomyomatosis renders tumor cells susceptible to cytotoxic T cells.
Klarquist J, Barfuss A, Kandala S, Reust MJ, Braun RK, Hu J, Dilling DF, McKee MD, Boissy RE, Love RB, Nishimura MI, Le Poole IC
Am J Pathol 2009 Dec;175(6):2463-72. Epub 2009 Nov 5 doi: 10.2353/ajpath.2009.090525. PMID: 19893037Free PMC Article
Normal lung function in subjects heterozygous for surfactant protein-B deficiency.
Yusen RD, Cohen AH, Hamvas A
Am J Respir Crit Care Med 1999 Feb;159(2):411-4. doi: 10.1164/ajrccm.159.2.9806033. PMID: 9927351

Therapy

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension.
Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B
Nat Commun 2020 Mar 4;11(1):1185. doi: 10.1038/s41467-020-14966-x. PMID: 32132543Free PMC Article
Sputum microbiota associated with new, recurrent and treatment failure tuberculosis.
Wu J, Liu W, He L, Huang F, Chen J, Cui P, Shen Y, Zhao J, Wang W, Zhang Y, Zhu M, Zhang W, Zhang Y
PLoS One 2013;8(12):e83445. Epub 2013 Dec 13 doi: 10.1371/journal.pone.0083445. PMID: 24349510Free PMC Article

Prognosis

From the archives of the AFIP: Lung disease in premature neonates: radiologic-pathologic correlation.
Agrons GA, Courtney SE, Stocker JT, Markowitz RI
Radiographics 2005 Jul-Aug;25(4):1047-73. doi: 10.1148/rg.254055019. PMID: 16009823
Normal lung function in subjects heterozygous for surfactant protein-B deficiency.
Yusen RD, Cohen AH, Hamvas A
Am J Respir Crit Care Med 1999 Feb;159(2):411-4. doi: 10.1164/ajrccm.159.2.9806033. PMID: 9927351

Clinical prediction guides

Dysregulation of PTEN in cardiopulmonary vascular remodeling induced by pulmonary hypertension.
Ravi Y, Selvendiran K, Meduru S, Citro L, Naidu S, Khan M, Rivera BK, Sai-Sudhakar CB, Kuppusamy P
Cell Biochem Biophys 2013 Nov;67(2):363-72. doi: 10.1007/s12013-011-9332-z. PMID: 22205501Free PMC Article
From the archives of the AFIP: Lung disease in premature neonates: radiologic-pathologic correlation.
Agrons GA, Courtney SE, Stocker JT, Markowitz RI
Radiographics 2005 Jul-Aug;25(4):1047-73. doi: 10.1148/rg.254055019. PMID: 16009823
Normal lung function in subjects heterozygous for surfactant protein-B deficiency.
Yusen RD, Cohen AH, Hamvas A
Am J Respir Crit Care Med 1999 Feb;159(2):411-4. doi: 10.1164/ajrccm.159.2.9806033. PMID: 9927351

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    Related information

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      Clinical tests in GTR
    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
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