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Metastatic Malignant Neoplasm in the Thoracic Cavity

MedGen UID:
1651966
•Concept ID:
C4744449
•
Neoplastic Process
Synonym: Metastatic Malignant Neoplasm in the Thorax

Definition

A malignant neoplasm that has spread to the thoracic cavity from another anatomic site. [from NCI]

Professional guidelines

PubMed

Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890
Initial staging of squamous cell carcinoma of the oral cavity, larynx and pharynx (excluding nasopharynx). Part 2: Remote extension assessment and exploration for secondary synchronous locations outside of the upper aerodigestive tract. 2012 SFORL guidelines.
de Monès E, Bertolus C, Salaun PY, Dubrulle F, Ferrié JC, Temam S, Chevalier D, Vergez S, Lagarde F, Schultz P, Lapeyre M, Barry B, Tronche S, de Raucourt D, Morinière S; Socéité Française de l'Otorhinolaryngologie
Eur Ann Otorhinolaryngol Head Neck Dis 2013 Apr;130(2):107-12. Epub 2012 Dec 28 doi: 10.1016/j.anorl.2012.09.003. PMID: 23273886
Thymoma: Diagnosis and treatment.
Singh G, Rumende CM, Amin Z
Acta Med Indones 2011 Jan;43(1):74-8. PMID: 21339550

Recent clinical studies

Etiology

Pulmonary metastasectomy with lymphadenectomy for colorectal pulmonary metastases: A systematic review.
van Dorp M, Bousema JE, Torensma B, Dickhoff C, van den Broek FJC, Schreurs WH, Gonzalez M, Kazemier G, Heineman DJ
Eur J Surg Oncol 2022 Jan;48(1):253-260. Epub 2021 Oct 11 doi: 10.1016/j.ejso.2021.09.020. PMID: 34656390
Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial.
Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, Kuebler WM, Herth FJF, Fan Y
Eur Respir J 2021 Dec;58(6) Epub 2021 Dec 9 doi: 10.1183/13993003.00055-2021. PMID: 33958432
Endobronchial Ultrasound Staging of Operable Non-small Cell Lung Cancer: Do Triple-Normal Lymph Nodes Require Routine Biopsy?
Hylton DA, Kidane B, Spicer J, Turner S, Churchill I, Sullivan K, Finley CJ, Shargall Y, Agzarian J, Seely AJE, Yasufuku K, Hanna WC; Canadian Association of Thoracic Surgery Research Group
Chest 2021 Jun;159(6):2470-2476. Epub 2021 Jan 9 doi: 10.1016/j.chest.2020.12.050. PMID: 33434503
Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, Asciak R, Hassan M, Piotrowska HE, Psallidas I, Rahman NM
Chest 2018 Nov;154(5):1115-1120. Epub 2018 Sep 20 doi: 10.1016/j.chest.2018.08.1031. PMID: 30243566
N2 disease in non-small-cell lung cancer: straight to surgery?
Sanchez-Lorente D, Guzman R, Boada M, Guirao A, Carriel N, Molins L
Future Oncol 2018 Mar;14(6s):13-16. doi: 10.2217/fon-2017-0387. PMID: 29664353

Diagnosis

Metastatic mediastinal hepatoid adenocarcinoma.
Caruana G, Cachia R, Micallef S, Sammut M, Psaila J
BMJ Case Rep 2024 Apr 9;17(4) doi: 10.1136/bcr-2022-253747. PMID: 38594200Free PMC Article
Mediastinal Lymphoproliferative Disorders.
Pina-Oviedo S
Adv Anat Pathol 2021 Sep 1;28(5):307-334. doi: 10.1097/PAP.0000000000000305. PMID: 34074861
Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial.
Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, Kuebler WM, Herth FJF, Fan Y
Eur Respir J 2021 Dec;58(6) Epub 2021 Dec 9 doi: 10.1183/13993003.00055-2021. PMID: 33958432
Immunotherapy-Induced Sarcoid-Like Reaction: A Shrewd Imitator.
Yasin H, Yadala V, Khan NAJ, Graffeo V, Denning K, Lebowicz Y
J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211009400. doi: 10.1177/23247096211009400. PMID: 33847154Free PMC Article
Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, Asciak R, Hassan M, Piotrowska HE, Psallidas I, Rahman NM
Chest 2018 Nov;154(5):1115-1120. Epub 2018 Sep 20 doi: 10.1016/j.chest.2018.08.1031. PMID: 30243566

Therapy

Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial.
Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, Kuebler WM, Herth FJF, Fan Y
Eur Respir J 2021 Dec;58(6) Epub 2021 Dec 9 doi: 10.1183/13993003.00055-2021. PMID: 33958432
Artificial pneumothorax improves radiofrequency ablation of pulmonary metastases of hepatocellular carcinoma close to mediastinum.
Zuo T, Lin W, Liu F, Xu J
BMC Cancer 2021 May 6;21(1):505. doi: 10.1186/s12885-021-08223-7. PMID: 33957875Free PMC Article
Immunotherapy-Induced Sarcoid-Like Reaction: A Shrewd Imitator.
Yasin H, Yadala V, Khan NAJ, Graffeo V, Denning K, Lebowicz Y
J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211009400. doi: 10.1177/23247096211009400. PMID: 33847154Free PMC Article
Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, Asciak R, Hassan M, Piotrowska HE, Psallidas I, Rahman NM
Chest 2018 Nov;154(5):1115-1120. Epub 2018 Sep 20 doi: 10.1016/j.chest.2018.08.1031. PMID: 30243566
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890

Prognosis

Pulmonary metastasectomy with lymphadenectomy for colorectal pulmonary metastases: A systematic review.
van Dorp M, Bousema JE, Torensma B, Dickhoff C, van den Broek FJC, Schreurs WH, Gonzalez M, Kazemier G, Heineman DJ
Eur J Surg Oncol 2022 Jan;48(1):253-260. Epub 2021 Oct 11 doi: 10.1016/j.ejso.2021.09.020. PMID: 34656390
Endobronchial Ultrasound Staging of Operable Non-small Cell Lung Cancer: Do Triple-Normal Lymph Nodes Require Routine Biopsy?
Hylton DA, Kidane B, Spicer J, Turner S, Churchill I, Sullivan K, Finley CJ, Shargall Y, Agzarian J, Seely AJE, Yasufuku K, Hanna WC; Canadian Association of Thoracic Surgery Research Group
Chest 2021 Jun;159(6):2470-2476. Epub 2021 Jan 9 doi: 10.1016/j.chest.2020.12.050. PMID: 33434503
Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, Asciak R, Hassan M, Piotrowska HE, Psallidas I, Rahman NM
Chest 2018 Nov;154(5):1115-1120. Epub 2018 Sep 20 doi: 10.1016/j.chest.2018.08.1031. PMID: 30243566
N2 disease in non-small-cell lung cancer: straight to surgery?
Sanchez-Lorente D, Guzman R, Boada M, Guirao A, Carriel N, Molins L
Future Oncol 2018 Mar;14(6s):13-16. doi: 10.2217/fon-2017-0387. PMID: 29664353
Surgical management of lung metastases.
Patrini D, Panagiotopoulos N, Lawrence D, Scarci M
Br J Hosp Med (Lond) 2017 Apr 2;78(4):192-198. doi: 10.12968/hmed.2017.78.4.192. PMID: 28398890

Clinical prediction guides

Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial.
Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, Kuebler WM, Herth FJF, Fan Y
Eur Respir J 2021 Dec;58(6) Epub 2021 Dec 9 doi: 10.1183/13993003.00055-2021. PMID: 33958432
Endobronchial Ultrasound Staging of Operable Non-small Cell Lung Cancer: Do Triple-Normal Lymph Nodes Require Routine Biopsy?
Hylton DA, Kidane B, Spicer J, Turner S, Churchill I, Sullivan K, Finley CJ, Shargall Y, Agzarian J, Seely AJE, Yasufuku K, Hanna WC; Canadian Association of Thoracic Surgery Research Group
Chest 2021 Jun;159(6):2470-2476. Epub 2021 Jan 9 doi: 10.1016/j.chest.2020.12.050. PMID: 33434503
The use of 18F-FDG positron emission tomography to detect mediastinal lymph nodes in metastatic breast cancer.
Onal C, Findikcioglu A, Guler OC, Reyhan M
Breast 2020 Dec;54:197-202. Epub 2020 Oct 26 doi: 10.1016/j.breast.2020.10.011. PMID: 33125983Free PMC Article
Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, Asciak R, Hassan M, Piotrowska HE, Psallidas I, Rahman NM
Chest 2018 Nov;154(5):1115-1120. Epub 2018 Sep 20 doi: 10.1016/j.chest.2018.08.1031. PMID: 30243566
ESTS guidelines for preoperative lymph node staging for non-small cell lung cancer.
De Leyn P, Lardinois D, Van Schil PE, Rami-Porta R, Passlick B, Zielinski M, Waller DA, Lerut T, Weder W
Eur J Cardiothorac Surg 2007 Jul;32(1):1-8. Epub 2007 Apr 19 doi: 10.1016/j.ejcts.2007.01.075. PMID: 17448671

Recent systematic reviews

Symptomatic secondary spinal arachnoid cysts: a systematic review.
Wang YB, Wang DH, Deng SL
Spine J 2023 Aug;23(8):1199-1211. Epub 2023 Mar 15 doi: 10.1016/j.spinee.2023.03.002. PMID: 36924909
Preoperative Staging by EBUS in cN0/N1 Lung Cancer: Systematic Review and Meta-Analysis.
Leong TL, Loveland PM, Gorelik A, Irving L, Steinfort DP
J Bronchology Interv Pulmonol 2019 Jul;26(3):155-165. doi: 10.1097/LBR.0000000000000545. PMID: 30119069
Endosonography Versus Mediastinoscopy in Mediastinal Staging of Lung Cancer: Systematic Review and Meta-Analysis.
Sehgal IS, Dhooria S, Aggarwal AN, Behera D, Agarwal R
Ann Thorac Surg 2016 Nov;102(5):1747-1755. doi: 10.1016/j.athoracsur.2016.05.110. PMID: 27637288
Status and prognosis of lymph node metastasis in patients with cardia cancer - a systematic review.
Okholm C, Svendsen LB, Achiam MP
Surg Oncol 2014 Sep;23(3):140-6. Epub 2014 Jun 11 doi: 10.1016/j.suronc.2014.06.001. PMID: 24953457
Meta-analysis of positron emission tomographic and computed tomographic imaging in detecting mediastinal lymph node metastases in nonsmall cell lung cancer.
Birim O, Kappetein AP, Stijnen T, Bogers AJ
Ann Thorac Surg 2005 Jan;79(1):375-82. doi: 10.1016/j.athoracsur.2004.06.041. PMID: 15620991

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