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Metastatic malignant neoplasm

MedGen UID:
422475
•Concept ID:
C2939419
•
Neoplastic Process
Synonyms: CA - Secondary cancer; malignant metastatic neoplasm; Metastases; Metastatic cancer; Metastatic Cancer; metastatic cancer; Metastatic malignant disease; Metastatic Malignant Neoplasm; metastatic malignant neoplasm; Metastatic neoplasm; Metastatic neoplasm (disease); metastatic neoplasm, malignant; Secondaries; Secondary cancer; Secondary malignant deposit; Secondary malignant neoplastic disease; Secondary tumor; Tumor metastasis
SNOMED CT: Metastatic neoplasm (disease) (128462008); Secondary malignant neoplastic disease (128462008); Metastatic cancer (128462008); CA - Secondary cancer (128462008); Metastases (128462008); Metastatic neoplasm (128462008); Secondaries (128462008); Secondary cancer (128462008); Metastatic malignant disease (128462008); Secondary tumor (128462008); Tumor metastasis (128462008); Secondary malignant deposit (128462008); Metastatic malignant neoplasm (128462008)
 
Monarch Initiative: MONDO:0024880

Definition

A malignant tumor that has spread from its original (primary) site of growth to another site close to or distant from the primary site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic malignant neoplasm

Professional guidelines

PubMed

European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023.
Peris K, Fargnoli MC, Kaufmann R, Arenberger P, Bastholt L, Seguin NB, Bataille V, Brochez L, Del Marmol V, Dummer R, Forsea AM, Gaudy-Marqueste C, Harwood CA, Hauschild A, Höller C, Kandolf L, Kellerners-Smeets NWJ, Lallas A, Leiter U, Malvehy J, Marinović B, Mijuskovic Z, Moreno-Ramirez D, Nagore E, Nathan P, Stratigos AJ, Stockfleth E, Tagliaferri L, Trakatelli M, Vieira R, Zalaudek I, Garbe C; EADO”A, EDF”B, ESTRO”C, UEMS”D and EADV”E
Eur J Cancer 2023 Oct;192:113254. Epub 2023 Jul 28 doi: 10.1016/j.ejca.2023.113254. PMID: 37604067
Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Hyperleukocytosis and leukostasis: management of a medical emergency.
Giammarco S, Chiusolo P, Piccirillo N, Di Giovanni A, Metafuni E, Laurenti L, Sica S, Pagano L
Expert Rev Hematol 2017 Feb;10(2):147-154. Epub 2016 Dec 26 doi: 10.1080/17474086.2017.1270754. PMID: 27967252

Recent clinical studies

Diagnosis

Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas.
Cimino-Mathews A, Subhawong AP, Elwood H, Warzecha HN, Sharma R, Park BH, Taube JM, Illei PB, Argani P
Hum Pathol 2013 Jun;44(6):959-65. Epub 2012 Dec 20 doi: 10.1016/j.humpath.2012.09.005. PMID: 23260325Free PMC Article
Palmar fasciitis and arthritis syndrome associated with metastatic ovarian cancer: a paraneoplastic syndrome.
Nahar IK, Al-Rajhi MS
Gulf J Oncolog 2012 Jul;(12):59-61. PMID: 22773217
Primitive neuroectodermal tumor of the ovary.
Anfinan NM, Sait KH, Al-Maghrabi JA
Saudi Med J 2008 Mar;29(3):444-6. PMID: 18327377

Therapy

Radical surgical cytoreduction of progressive leiomyomatosis peritonealis disseminata: a case report.
Kratz KG, Santillan A, Gu M, Bristow RE
J Reprod Med 2009 Jul;54(7):447-50. PMID: 19691262

Prognosis

Palmar fasciitis and arthritis syndrome associated with metastatic ovarian cancer: a paraneoplastic syndrome.
Nahar IK, Al-Rajhi MS
Gulf J Oncolog 2012 Jul;(12):59-61. PMID: 22773217
Primitive neuroectodermal tumor of the ovary.
Anfinan NM, Sait KH, Al-Maghrabi JA
Saudi Med J 2008 Mar;29(3):444-6. PMID: 18327377

Supplemental Content

Table of contents

    Clinical resources

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