U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Paratesticular Soft Tissue Neoplasm

MedGen UID:
1694562
•Concept ID:
C5206595
•
Neoplastic Process
Synonym: Paratesticular Mesenchymal Neoplasm

Definition

A mesenchymal neoplasm that arises from the paratesticular region. [from NCI]

Professional guidelines

PubMed

Safety and efficacy of intensity-modulated radiotherapy in the management of spermatic cord sarcoma.
Cerda T, Martin É, Truc G, Créhange G, Maingon P
Cancer Radiother 2017 Feb;21(1):16-20. Epub 2016 Dec 29 doi: 10.1016/j.canrad.2016.07.102. PMID: 28041814
Outcome, Treatment, and Treatment Failures in Patients Suffering Localized Embryonal Paratesticular Rhabdomyosarcoma: Results From the "Cooperative Weichteilsarkom Studiengruppe" Trials CWS-86, -91, -96, and -2002P.
Seitz G, Fuchs J, Martus P, Klingebiel T, Leuschner I, Schuck A, Dantonello TM, Koscielniak E; Cooperative Weichteilsarkom Studiengruppe (CWS).
Ann Surg 2016 Dec;264(6):1148-1155. doi: 10.1097/SLA.0000000000001550. PMID: 27828824
Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group.
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2016 Oct;23(11):3531-3540. Epub 2016 Aug 1 doi: 10.1245/s10434-016-5336-7. PMID: 27480354Free PMC Article

Recent clinical studies

Etiology

Clinicopathologic features, outcomes, and prognostic factors of testicular sarcoma: a population-based study.
Bhambhvani HP, Greenberg DR, Kasman AM, Eisenberg ML
Int Urol Nephrol 2021 Feb;53(2):257-267. Epub 2020 Sep 7 doi: 10.1007/s11255-020-02634-4. PMID: 32895865
Paratesticular Sarcoma: Typical Presentation, Imaging Features, and Clinical Challenges.
Ap Dafydd D, Messiou C, Thway K, Strauss DC, Nicol DL, Moskovic E
Urology 2017 Feb;100:163-168. Epub 2016 Sep 14 doi: 10.1016/j.urology.2016.09.005. PMID: 27639792
Future directions in risk stratification and therapy for advanced pediatric genitourinary rhabdomyosarcoma.
Harel M, Ferrer FA, Shapiro LH, Makari JH
Urol Oncol 2016 Feb;34(2):103-15. Epub 2015 Oct 28 doi: 10.1016/j.urolonc.2015.09.013. PMID: 26519985
Paratesticular rhabdomyosarcoma.
de Vries JD
World J Urol 1995;13(4):219-25. doi: 10.1007/BF00182966. PMID: 8528295
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Diagnosis

Paratesticular Sarcoma: Typical Presentation, Imaging Features, and Clinical Challenges.
Ap Dafydd D, Messiou C, Thway K, Strauss DC, Nicol DL, Moskovic E
Urology 2017 Feb;100:163-168. Epub 2016 Sep 14 doi: 10.1016/j.urology.2016.09.005. PMID: 27639792
Impact of hemiscrotectomy on outcome of patients with embryonal paratesticular rhabdomyosarcoma: results from the Cooperative Soft Tissue Sarcoma Group Studies CWS-86, 91, 96 and 2002P.
Seitz G, Dantonello TM, Kosztyla D, Klingebiel T, Leuschner I, Fuchs J, Koscielniak E; Cooperative Soft Tissue Sarcoma Study Group
J Urol 2014 Sep;192(3):902-7. Epub 2014 Mar 12 doi: 10.1016/j.juro.2014.03.005. PMID: 24631108
Well-differentiated liposarcoma (atypical lipomatous tumors).
Laurino L, Furlanetto A, Orvieto E, Dei Tos AP
Semin Diagn Pathol 2001 Nov;18(4):258-62. PMID: 11757865
Paratesticular rhabdomyosarcoma.
de Vries JD
World J Urol 1995;13(4):219-25. doi: 10.1007/BF00182966. PMID: 8528295
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Therapy

Safety and efficacy of intensity-modulated radiotherapy in the management of spermatic cord sarcoma.
Cerda T, Martin É, Truc G, Créhange G, Maingon P
Cancer Radiother 2017 Feb;21(1):16-20. Epub 2016 Dec 29 doi: 10.1016/j.canrad.2016.07.102. PMID: 28041814
Is alveolar histotype a prognostic factor in paratesticular rhabdomyosarcoma? The experience of Italian and German Soft Tissue Sarcoma Cooperative Group.
Ferrari A, Bisogno G, Casanova M, Brecht IB, Alaggio R, Cecchetto G, Provenzi M, Koscielniak E, Treuner J, Carli M
Pediatr Blood Cancer 2004 Feb;42(2):134-8. doi: 10.1002/pbc.10460. PMID: 14752876
Desmoplastic small round cell tumour in children and adolescents.
Bisogno G, Roganovich J, Sotti G, Ninfo V, di Montezemolo LC, Donfrancesco A, Mascarin M, Carli M
Med Pediatr Oncol 2000 May;34(5):338-42. doi: 10.1002/(sici)1096-911x(200005)34:5<338::aid-mpo4>3.0.co;2-0. PMID: 10797355
Late effects of therapy in patients with paratesticular rhabdomyosarcoma. Intergroup Rhabdomyosarcoma Study Committee.
Heyn R, Raney RB Jr, Hays DM, Tefft M, Gehan E, Webber B, Maurer HM
J Clin Oncol 1992 Apr;10(4):614-23. doi: 10.1200/JCO.1992.10.4.614. PMID: 1548524
Treatment of soft tissue sarcoma in childhood and adolescence. A report of the German Cooperative Soft Tissue Sarcoma Study.
Koscielniak E, Jürgens H, Winkler K, Bürger D, Herbst M, Keim M, Bernhard G, Treuner J
Cancer 1992 Nov 15;70(10):2557-67. doi: 10.1002/1097-0142(19921115)70:10<2557::aid-cncr2820701027>3.0.co;2-8. PMID: 1482503

Prognosis

Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
Routh JC, Dasgupta R, Chi YY, Shnorhavorian M, Tian J, Walterhouse DO, Breneman J, Wolden SL, Arndt CA, Hawkins DS, Rodeberg DA
Int J Cancer 2020 Dec 1;147(11):3168-3176. Epub 2020 Jul 11 doi: 10.1002/ijc.33143. PMID: 32525556Free PMC Article
Paratesticular rhabdomyosarcoma with metastatic encasement of the abdominal aorta.
Aquino MR, Gibson DP, Bloom DA
Pediatr Radiol 2011 Aug;41(8):1061-4. Epub 2011 Jan 22 doi: 10.1007/s00247-010-1964-4. PMID: 21258928
Paratesticular rhabdomyosarcoma.
de Vries JD
World J Urol 1995;13(4):219-25. doi: 10.1007/BF00182966. PMID: 8528295
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580
Diagnosis and behavior of juvenile rhabdomyosarcoma.
Bale PM, Parsons RE, Stevens MM
Hum Pathol 1983 Jul;14(7):596-611. doi: 10.1016/s0046-8177(83)80203-2. PMID: 6862431

Clinical prediction guides

Clinicopathologic features, outcomes, and prognostic factors of testicular sarcoma: a population-based study.
Bhambhvani HP, Greenberg DR, Kasman AM, Eisenberg ML
Int Urol Nephrol 2021 Feb;53(2):257-267. Epub 2020 Sep 7 doi: 10.1007/s11255-020-02634-4. PMID: 32895865
Dedifferentiated Liposarcoma With Meningothelial-Like Whorls: Five Additional Cases and Review of the Literature.
Usman Tariq M, Kayani N, Moatter T, Din NU
Int J Surg Pathol 2020 Oct;28(7):749-758. Epub 2020 May 17 doi: 10.1177/1066896920921950. PMID: 32419561
Paratesticular rhabdomyosarcoma: Importance of initial therapy.
Hammond WJ, Farber BA, Price AP, Wolden SL, Heaton TE, Wexler LH, La Quaglia MP
J Pediatr Surg 2017 Feb;52(2):304-308. Epub 2016 Nov 14 doi: 10.1016/j.jpedsurg.2016.11.027. PMID: 27894767Free PMC Article
Impact of hemiscrotectomy on outcome of patients with embryonal paratesticular rhabdomyosarcoma: results from the Cooperative Soft Tissue Sarcoma Group Studies CWS-86, 91, 96 and 2002P.
Seitz G, Dantonello TM, Kosztyla D, Klingebiel T, Leuschner I, Fuchs J, Koscielniak E; Cooperative Soft Tissue Sarcoma Study Group
J Urol 2014 Sep;192(3):902-7. Epub 2014 Mar 12 doi: 10.1016/j.juro.2014.03.005. PMID: 24631108
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Recent systematic reviews

Optimal treatment strategy for paratesticular liposarcoma: retrospective analysis of 265 reported cases.
Kamitani R, Matsumoto K, Takeda T, Mizuno R, Oya M
Int J Clin Oncol 2020 Dec;25(12):2099-2106. Epub 2020 Jul 26 doi: 10.1007/s10147-020-01753-3. PMID: 32715355

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...