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Advanced Gastric Adenocarcinoma

MedGen UID:
1708925
Concept ID:
C5237824
Neoplastic Process

Definition

Gastric adenocarcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Gastric Adenocarcinoma

Professional guidelines

PubMed

Srikumar T, Sundar R
Surg Clin North Am 2025 Feb;105(1):75-94. Epub 2024 Oct 15 doi: 10.1016/j.suc.2024.06.007. PMID: 39523078
Depotte L, Palle J, Rasola C, Broudin C, Afrăsânie VA, Mariani A, Zaanan A
Clin Res Hepatol Gastroenterol 2024 Jan;48(1):102245. Epub 2023 Nov 11 doi: 10.1016/j.clinre.2023.102245. PMID: 37952913
Lumish MA, Ku GY
Curr Treat Options Oncol 2022 Jul;23(7):1044-1058. Epub 2022 May 7 doi: 10.1007/s11864-021-00917-1. PMID: 35524838

Recent clinical studies

Etiology

Tian Y, Yang P, Guo H, Liu Y, Zhang Z, Ding P, Zheng T, Deng H, Ma W, Li Y, Fan L, Zhang Z, Wang D, Zhao X, Tan B, Liu Y, Zhao Q
Int J Surg 2023 Dec 1;109(12):4000-4008. doi: 10.1097/JS9.0000000000000692. PMID: 37678277Free PMC Article
Pádua JDB, Mariano CFA, Fabro AT, Tirapelli DPDC, Sankarankutty AK, Dos Santos JS, Brunaldi MO
J Histochem Cytochem 2022 Mar;70(3):199-210. Epub 2022 Jan 3 doi: 10.1369/00221554211065834. PMID: 34978208Free PMC Article
Papageorge MV, de Geus SWL, Zheng J, Woods AP, Ng SC, Cassidy MR, McAneny D, Tseng JF, Sachs TE
J Gastrointest Surg 2021 Jun;25(6):1363-1369. Epub 2021 Apr 12 doi: 10.1007/s11605-021-04993-4. PMID: 33846934
Pourghasemian M, Danandeh Mehr A, Molaei M, Habibzadeh A
Asian Pac J Cancer Prev 2020 Aug 1;21(8):2337-2341. doi: 10.31557/APJCP.2020.21.8.2337. PMID: 32856863Free PMC Article
Hu YL, Pang W, Huang Y, Zhang Y, Zhang CJ
Front Cell Infect Microbiol 2018;8:433. Epub 2018 Dec 12 doi: 10.3389/fcimb.2018.00433. PMID: 30619779Free PMC Article

Diagnosis

Hu D, Zhou X, Si X
Gastrointest Endosc 2023 Aug;98(2):257-258. Epub 2023 May 4 doi: 10.1016/j.gie.2023.04.2084. PMID: 37146950
Lumish MA, Ku GY
Curr Treat Options Oncol 2022 Jul;23(7):1044-1058. Epub 2022 May 7 doi: 10.1007/s11864-021-00917-1. PMID: 35524838
Papageorge MV, de Geus SWL, Zheng J, Woods AP, Ng SC, Cassidy MR, McAneny D, Tseng JF, Sachs TE
J Gastrointest Surg 2021 Jun;25(6):1363-1369. Epub 2021 Apr 12 doi: 10.1007/s11605-021-04993-4. PMID: 33846934
Hu YL, Pang W, Huang Y, Zhang Y, Zhang CJ
Front Cell Infect Microbiol 2018;8:433. Epub 2018 Dec 12 doi: 10.3389/fcimb.2018.00433. PMID: 30619779Free PMC Article
Blum M, Suzuki A, Ajani JA
Future Oncol 2011 Jun;7(6):715-26. doi: 10.2217/fon.11.50. PMID: 21675835

Therapy

Depotte L, Palle J, Rasola C, Broudin C, Afrăsânie VA, Mariani A, Zaanan A
Clin Res Hepatol Gastroenterol 2024 Jan;48(1):102245. Epub 2023 Nov 11 doi: 10.1016/j.clinre.2023.102245. PMID: 37952913
Zhang Y, Qiu MZ, Wang JF, Zhang YQ, Shen A, Yuan XL, Zhang T, Wei XL, Zhao HY, Wang DS, Zhao Q, Xiong GZ, Ji YP, Liang XJ, Xia G, Xu RH
Cell Rep Med 2022 Nov 15;3(11):100814. doi: 10.1016/j.xcrm.2022.100814. PMID: 36384091Free PMC Article
Scott LJ
Drugs 2018 May;78(7):747-758. doi: 10.1007/s40265-018-0903-9. PMID: 29663291
Mizrak Kaya D, Harada K, Shimodaira Y, Amlashi FG, Lin Q, Ajani JA
Expert Rev Clin Pharmacol 2017 Mar;10(3):263-271. Epub 2017 Feb 3 doi: 10.1080/17512433.2017.1279969. PMID: 28094573
Swisher SG, Pisters PW, Komaki R, Lahoti S, Ajani JA
Curr Treat Options Oncol 2000 Dec;1(5):387-98. doi: 10.1007/s11864-000-0066-1. PMID: 12057146

Prognosis

Depotte L, Palle J, Rasola C, Broudin C, Afrăsânie VA, Mariani A, Zaanan A
Clin Res Hepatol Gastroenterol 2024 Jan;48(1):102245. Epub 2023 Nov 11 doi: 10.1016/j.clinre.2023.102245. PMID: 37952913
Yoon C, Lu J, Kim BJ, Cho SJ, Kim JH, Moy RH, Ryeom SW, Yoon SS
J Gastrointest Surg 2023 Apr;27(4):666-676. Epub 2023 Jan 10 doi: 10.1007/s11605-022-05568-7. PMID: 36627466
Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, Calin GA, Mazur PK, Hanash SM, Ishizawa J, Hirata Y, Nagano O, Wang Z, Wang L, Xian W, McKeon F, Ajani JA, Song S
Gut 2023 Apr;72(4):624-637. Epub 2022 Aug 24 doi: 10.1136/gutjnl-2021-326581. PMID: 36002248
Papageorge MV, de Geus SWL, Zheng J, Woods AP, Ng SC, Cassidy MR, McAneny D, Tseng JF, Sachs TE
J Gastrointest Surg 2021 Jun;25(6):1363-1369. Epub 2021 Apr 12 doi: 10.1007/s11605-021-04993-4. PMID: 33846934
Scott LJ
Drugs 2018 May;78(7):747-758. doi: 10.1007/s40265-018-0903-9. PMID: 29663291

Clinical prediction guides

Yoon C, Lu J, Kim BJ, Cho SJ, Kim JH, Moy RH, Ryeom SW, Yoon SS
J Gastrointest Surg 2023 Apr;27(4):666-676. Epub 2023 Jan 10 doi: 10.1007/s11605-022-05568-7. PMID: 36627466
Margalit O, Yu S, Shacham-Shmueli E, Strauss G, Yang YX, Lawrence YR, Reiss KA, Golan T, Halpern N, Aderka D, Giantonio B, Mamtani R, Boursi B
J Cancer Res Clin Oncol 2022 Jul;148(7):1703-1708. Epub 2022 Jan 23 doi: 10.1007/s00432-021-03911-0. PMID: 35066662
Papageorge MV, de Geus SWL, Zheng J, Woods AP, Ng SC, Cassidy MR, McAneny D, Tseng JF, Sachs TE
J Gastrointest Surg 2021 Jun;25(6):1363-1369. Epub 2021 Apr 12 doi: 10.1007/s11605-021-04993-4. PMID: 33846934
Brenkman HJF, Gertsen EC, Vegt E, van Hillegersberg R, van Berge Henegouwen MI, Gisbertz SS, Luyer MDP, Nieuwenhuijzen GAP, van Lanschot JJB, Lagarde SM, de Steur WO, Hartgrink HH, Stoot JHMB, Hulsewe KWE, Spillenaar Bilgen EJ, van Det MJ, Kouwenhoven EA, van der Peet DL, Daams F, van Sandick JW, van Grieken NCT, Heisterkamp J, van Etten B, Haveman JW, Pierie JP, Jonker F, Thijssen AY, Belt EJT, van Duijvendijk P, Wassenaar E, van Laarhoven HWM, Wessels FJ, Haj Mohammad N, van Stel HF, Frederix GWJ, Siersema PD, Ruurda JP; PLASTIC Study Group
BMC Cancer 2018 Apr 20;18(1):450. doi: 10.1186/s12885-018-4367-9. PMID: 29678145Free PMC Article
Blum M, Suzuki A, Ajani JA
Future Oncol 2011 Jun;7(6):715-26. doi: 10.2217/fon.11.50. PMID: 21675835

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