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Myeloid Neoplasm Finding

MedGen UID:: 1717391
•Concept ID:: C5238554
•: Finding

Definition

A term that refers to clinicopathologic findings related to myeloid neoplasms. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMyeloid Neoplasm Finding

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Site or System
    - Hematopoietic system finding
      - Myeloid Neoplasm Finding
        High Grade Myeloid Neoplasm
        High Risk Chronic Myelogenous Leukemia, BCR-ABL1 Positive
        High Risk Chronic Myelomonocytic Leukemia
        Recurrent High Risk Chronic Myelomonocytic Leukemia
        Refractory High Risk Chronic Myelomonocytic Leukemia
        High Risk Myelodysplastic Syndrome
        Recurrent High Risk Myelodysplastic Syndrome
        Refractory High Risk Myelodysplastic Syndrome
        Higher Risk Myelodysplastic Syndrome
        Recurrent Higher Risk Myelodysplastic Syndrome
        Refractory Higher Risk Myelodysplastic Syndrome
        Intermediate Risk Acute Myeloid Leukemia
        Normal Karyotype Intermediate Risk Acute Myeloid Leukemia
        Refractory Intermediate Risk Acute Myeloid Leukemia
        Myeloid Leukemia in Remission
        Acute Myeloid Leukemia in Remission
        Acute Erythroid Leukemia in Remission
        Acute Monoblastic and Monocytic Leukemia in Remission
        Acute Monocytic Leukemia in Remission
        Acute Myeloid Leukemia with Multilineage Dysplasia in Remission
        Acute Myelomonocytic Leukemia in Remission
        Adult Acute Myeloid Leukemia in Remission
        Childhood Acute Myeloid Leukemia in Remission
        Myeloid Sarcoma in Remission
        Childhood Myeloid Leukemia in Remission
        Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission
        Chronic Myelomonocytic Leukemia in Remission
        Non-M3 Acute Myeloid Leukemia
        Previously Treated Myelodysplastic Syndrome
        Untreated Adult Acute Myeloid Leukemia
        Untreated Childhood Myeloid Neoplasm
        Very High Risk Chronic Myelogenous Leukemia, BCR-ABL1 Positive
        Very High Risk Myelodysplastic Syndrome
        Recurrent Very High Risk Myelodysplastic Syndrome
        Refractory Very High Risk Myelodysplastic Syndrome

Professional guidelines

PubMed

Myelodysplastic syndromes: 2023 update on diagnosis, risk-stratification, and management.

Garcia-Manero G
Am J Hematol 2023 Aug;98(8):1307-1325. Epub 2023 Jun 8 doi: 10.1002/ajh.26984. PMID: 37288607

Acute myeloid leukemia: 2023 update on diagnosis, risk-stratification, and management.

Shimony S, Stahl M, Stone RM
Am J Hematol 2023 Mar;98(3):502-526. Epub 2023 Jan 13 doi: 10.1002/ajh.26822. PMID: 36594187

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.

Sekeres MA, Taylor J
JAMA 2022 Sep 6;328(9):872-880. doi: 10.1001/jama.2022.14578. PMID: 36066514

See all (3060)

Recent clinical studies

Etiology

Acute myeloid leukaemia.

DiNardo CD, Erba HP, Freeman SD, Wei AH
Lancet 2023 Jun 17;401(10393):2073-2086. Epub 2023 Apr 15 doi: 10.1016/S0140-6736(23)00108-3. PMID: 37068505

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.

Sekeres MA, Taylor J
JAMA 2022 Sep 6;328(9):872-880. doi: 10.1001/jama.2022.14578. PMID: 36066514

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.

Döhner H, Wei AH, Appelbaum FR, Craddock C, DiNardo CD, Dombret H, Ebert BL, Fenaux P, Godley LA, Hasserjian RP, Larson RA, Levine RL, Miyazaki Y, Niederwieser D, Ossenkoppele G, Röllig C, Sierra J, Stein EM, Tallman MS, Tien HF, Wang J, Wierzbowska A, Löwenberg B
Blood 2022 Sep 22;140(12):1345-1377. doi: 10.1182/blood.2022016867. PMID: 35797463

Cancer Stem Cells-Origins and Biomarkers: Perspectives for Targeted Personalized Therapies.

Walcher L, Kistenmacher AK, Suo H, Kitte R, Dluczek S, Strauß A, Blaudszun AR, Yevsa T, Fricke S, Kossatz-Boehlert U
Front Immunol 2020;11:1280. Epub 2020 Aug 7 doi: 10.3389/fimmu.2020.01280. PMID: 32849491 Free PMC Article

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.

Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz M, Sierra J, Tallman MS, Tien HF, Wei AH, Löwenberg B, Bloomfield CD
Blood 2017 Jan 26;129(4):424-447. Epub 2016 Nov 28 doi: 10.1182/blood-2016-08-733196. PMID: 27895058 Free PMC Article

See all (18298)

Diagnosis

Acute myeloid leukaemia.

DiNardo CD, Erba HP, Freeman SD, Wei AH
Lancet 2023 Jun 17;401(10393):2073-2086. Epub 2023 Apr 15 doi: 10.1016/S0140-6736(23)00108-3. PMID: 37068505

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.

Sekeres MA, Taylor J
JAMA 2022 Sep 6;328(9):872-880. doi: 10.1001/jama.2022.14578. PMID: 36066514

Molecular and cellular markers for measurable residual disease in acute lymphoblastic leukemia.

Juárez-Avendaño G, Méndez-Ramírez N, Luna-Silva NC, Gómez-Almaguer D, Pelayo R, Balandrán JC
Bol Med Hosp Infant Mex 2021;78(3):159-170. doi: 10.24875/BMHIM.20000155. PMID: 34167145

Cancer Stem Cells-Origins and Biomarkers: Perspectives for Targeted Personalized Therapies.

Acute Myeloid Leukemia Immunophenotyping by Flow Cytometric Analysis.

Chen X, Cherian S
Clin Lab Med 2017 Dec;37(4):753-769. Epub 2017 Aug 31 doi: 10.1016/j.cll.2017.07.003. PMID: 29128067

See all (23632)

Therapy

Myelodysplastic syndromes: 2023 update on diagnosis, risk-stratification, and management.

Garcia-Manero G
Am J Hematol 2023 Aug;98(8):1307-1325. Epub 2023 Jun 8 doi: 10.1002/ajh.26984. PMID: 37288607

Molecular correlates of clinical response and resistance to atezolizumab in combination with bevacizumab in advanced hepatocellular carcinoma.

Zhu AX, Abbas AR, de Galarreta MR, Guan Y, Lu S, Koeppen H, Zhang W, Hsu CH, He AR, Ryoo BY, Yau T, Kaseb AO, Burgoyne AM, Dayyani F, Spahn J, Verret W, Finn RS, Toh HC, Lujambio A, Wang Y
Nat Med 2022 Aug;28(8):1599-1611. Epub 2022 Jun 23 doi: 10.1038/s41591-022-01868-2. PMID: 35739268

CPX-351 (vyxeos) in AML.

Alfayez M, Kantarjian H, Kadia T, Ravandi-Kashani F, Daver N
Leuk Lymphoma 2020 Feb;61(2):288-297. Epub 2019 Sep 24 doi: 10.1080/10428194.2019.1660970. PMID: 31547736

Maintenance therapy in AML: The past, the present and the future.

Molica M, Breccia M, Foa R, Jabbour E, Kadia TM
Am J Hematol 2019 Nov;94(11):1254-1265. Epub 2019 Sep 11 doi: 10.1002/ajh.25620. PMID: 31429099

MDS overlap disorders and diagnostic boundaries.

Tanaka TN, Bejar R
Blood 2019 Mar 7;133(10):1086-1095. Epub 2019 Jan 22 doi: 10.1182/blood-2018-10-844670. PMID: 30670443

See all (18531)

Prognosis

Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia.

Uy GL, Aldoss I, Foster MC, Sayre PH, Wieduwilt MJ, Advani AS, Godwin JE, Arellano ML, Sweet KL, Emadi A, Ravandi F, Erba HP, Byrne M, Michaelis L, Topp MS, Vey N, Ciceri F, Carrabba MG, Paolini S, Huls GA, Jongen-Lavrencic M, Wermke M, Chevallier P, Gyan E, Récher C, Stiff PJ, Pettit KM, Löwenberg B, Church SE, Anderson E, Vadakekolathu J, Santaguida M, Rettig MP, Muth J, Curtis T, Fehr E, Guo K, Zhao J, Bakkacha O, Jacobs K, Tran K, Kaminker P, Kostova M, Bonvini E, Walter RB, Davidson-Moncada JK, Rutella S, DiPersio JF
Blood 2021 Feb 11;137(6):751-762. doi: 10.1182/blood.2020007732. PMID: 32929488 Free PMC Article

Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults.

Moore SC, Lee IM, Weiderpass E, Campbell PT, Sampson JN, Kitahara CM, Keadle SK, Arem H, Berrington de Gonzalez A, Hartge P, Adami HO, Blair CK, Borch KB, Boyd E, Check DP, Fournier A, Freedman ND, Gunter M, Johannson M, Khaw KT, Linet MS, Orsini N, Park Y, Riboli E, Robien K, Schairer C, Sesso H, Spriggs M, Van Dusen R, Wolk A, Matthews CE, Patel AV
JAMA Intern Med 2016 Jun 1;176(6):816-25. doi: 10.1001/jamainternmed.2016.1548. PMID: 27183032 Free PMC Article

Pathogenesis, diagnosis, and management of cholangiocarcinoma.

Ilyas SI, Gores GJ
Gastroenterology 2013 Dec;145(6):1215-29. Epub 2013 Oct 15 doi: 10.1053/j.gastro.2013.10.013. PMID: 24140396 Free PMC Article

Acute myeloid leukemia: epidemiology and etiology.

Deschler B, Lübbert M
Cancer 2006 Nov 1;107(9):2099-107. doi: 10.1002/cncr.22233. PMID: 17019734

The childhood leukemias.

Colby-Graham MF, Chordas C
J Pediatr Nurs 2003 Apr;18(2):87-95. doi: 10.1053/jpdn.2003.9. PMID: 12720205

See all (20361)

Clinical prediction guides

Management of Patients with Lower-Risk Myelodysplastic Neoplasms (MDS).

Lucero J, Al-Harbi S, Yee KWL
Curr Oncol 2023 Jun 27;30(7):6177-6196. doi: 10.3390/curroncol30070459. PMID: 37504319 Free PMC Article

Myelodysplastic syndromes: 2023 update on diagnosis, risk-stratification, and management.

Garcia-Manero G
Am J Hematol 2023 Aug;98(8):1307-1325. Epub 2023 Jun 8 doi: 10.1002/ajh.26984. PMID: 37288607

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.

Sekeres MA, Taylor J
JAMA 2022 Sep 6;328(9):872-880. doi: 10.1001/jama.2022.14578. PMID: 36066514

Prognostic versus predictive value of biomarkers in oncology.

Oldenhuis CN, Oosting SF, Gietema JA, de Vries EG
Eur J Cancer 2008 May;44(7):946-53. Epub 2008 Apr 7 doi: 10.1016/j.ejca.2008.03.006. PMID: 18396036

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.

Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES
Science 1999 Oct 15;286(5439):531-7. doi: 10.1126/science.286.5439.531. PMID: 10521349

See all (14070)

Recent systematic reviews

Anthracyclines and the risk of arrhythmias: A systematic review and meta-analysis.

Dean YE, Dahshan H, Motawea KR, Khalifa Z, Tanas Y, Rakha I, Hasan W, Kishk M, Mahmoud A, Elsayed A, Abdelkader O, Tokunaga A, Khalifa A, Helmy A, Elhalag RH, Farghaly RM, Abdelkader OKS, Shah J, Hakim D, Aiash H
Medicine (Baltimore) 2023 Nov 17;102(46):e35770. doi: 10.1097/MD.0000000000035770. PMID: 37986405 Free PMC Article

Therapies for acute myeloid leukemia in patients ineligible for standard induction chemotherapy: a systematic review.

Heuser M, Fernandez C, Hauch O, Klibanov OM, Chaudhary T, Rives V
Future Oncol 2023 Apr;19(11):789-810. Epub 2023 May 12 doi: 10.2217/fon-2022-1286. PMID: 37170899

Treatment outcomes for newly diagnosed, treatment-naïve TP53-mutated acute myeloid leukemia: a systematic review and meta-analysis.

Daver NG, Iqbal S, Renard C, Chan RJ, Hasegawa K, Hu H, Tse P, Yan J, Zoratti MJ, Xie F, Ramsingh G
J Hematol Oncol 2023 Mar 6;16(1):19. doi: 10.1186/s13045-023-01417-5. PMID: 36879351 Free PMC Article

Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies.

Larsson SC, Burgess S
EBioMedicine 2022 Aug;82:104154. Epub 2022 Jul 8 doi: 10.1016/j.ebiom.2022.104154. PMID: 35816897 Free PMC Article

Association of Measurable Residual Disease With Survival Outcomes in Patients With Acute Myeloid Leukemia: A Systematic Review and Meta-analysis.

Short NJ, Zhou S, Fu C, Berry DA, Walter RB, Freeman SD, Hourigan CS, Huang X, Nogueras Gonzalez G, Hwang H, Qi X, Kantarjian H, Ravandi F
JAMA Oncol 2020 Dec 1;6(12):1890-1899. doi: 10.1001/jamaoncol.2020.4600. PMID: 33030517 Free PMC Article

See all (238)

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Myeloid Neoplasm Finding

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

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