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Advanced Basal Cell Carcinoma

MedGen UID:
1751731
Concept ID:
C5419609
Neoplastic Process

Definition

Basal cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Basal Cell Carcinoma

Professional guidelines

PubMed

Villani A, Potestio L, Fabbrocini G, Scalvenzi M
Adv Ther 2022 Mar;39(3):1164-1178. Epub 2022 Jan 28 doi: 10.1007/s12325-022-02044-1. PMID: 35089534Free PMC Article
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Puig S, Berrocal A
Clin Transl Oncol 2015 Jul;17(7):497-503. Epub 2015 Feb 3 doi: 10.1007/s12094-014-1272-9. PMID: 25643667Free PMC Article

Recent clinical studies

Etiology

Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Dummer R, Guminksi A, Gutzmer R, Lear JT, Lewis KD, Chang ALS, Combemale P, Dirix L, Kaatz M, Kudchadkar R, Loquai C, Plummer R, Schulze HJ, Stratigos AJ, Trefzer U, Squittieri N, Migden MR
Br J Dermatol 2020 Jun;182(6):1369-1378. Epub 2019 Dec 8 doi: 10.1111/bjd.18552. PMID: 31545507Free PMC Article
Amici JM, Battistella M, Beylot-Barry M, Chatellier A, Dalac-Ra S, Dreno B, Falandry C, Froget N, Giacchero D, Grob JJ, Guerreschir P, Leccia MT, Malard O, Mortier L, Routier E, Stefan A, Stefan D, Stoebner PE, Basset-Seguin N
Eur J Dermatol 2015 Nov-Dec;25(6):586-94. doi: 10.1684/ejd.2015.2641. PMID: 26574792
Puig S, Berrocal A
Clin Transl Oncol 2015 Jul;17(7):497-503. Epub 2015 Feb 3 doi: 10.1007/s12094-014-1272-9. PMID: 25643667Free PMC Article

Diagnosis

Krakowski AC, Hafeez F, Westheim A, Pan EY, Wilson M
J Am Acad Dermatol 2022 Jun;86(6S):S1-S13. doi: 10.1016/j.jaad.2022.03.023. PMID: 35577405
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Giavedoni P, Puig S, Carrera C
Semin Cutan Med Surg 2016 Mar;35(1):31-41. doi: 10.12788/j.sder.2016.014. PMID: 26963115
Peris K, Licitra L, Ascierto PA, Corvò R, Simonacci M, Picciotto F, Gualdi G, Pellacani G, Santoro A
Future Oncol 2015;11(4):703-12. doi: 10.2217/fon.14.281. PMID: 25686123
Haves AW, Schaffer PR, Carucci JA
J Drugs Dermatol 2013 Oct;12(10 Suppl):s151-3. PMID: 24085061

Therapy

Villani A, Potestio L, Fabbrocini G, Scalvenzi M
Adv Ther 2022 Mar;39(3):1164-1178. Epub 2022 Jan 28 doi: 10.1007/s12325-022-02044-1. PMID: 35089534Free PMC Article
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Dummer R, Ascierto PA, Basset-Seguin N, Dréno B, Garbe C, Gutzmer R, Hauschild A, Krattinger R, Lear JT, Malvehy J, Schadendorf D, Grob JJ
J Eur Acad Dermatol Venereol 2020 Sep;34(9):1944-1956. Epub 2020 Mar 4 doi: 10.1111/jdv.16230. PMID: 31990414
Sekulic A, Migden MR, Oro AE, Dirix L, Lewis KD, Hainsworth JD, Solomon JA, Yoo S, Arron ST, Friedlander PA, Marmur E, Rudin CM, Chang AL, Low JA, Mackey HM, Yauch RL, Graham RA, Reddy JC, Hauschild A
N Engl J Med 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713. PMID: 22670903Free PMC Article
Dlugosz A, Agrawal S, Kirkpatrick P
Nat Rev Drug Discov 2012 Jun 1;11(6):437-8. doi: 10.1038/nrd3753. PMID: 22653209Free PMC Article

Prognosis

Sternfeld A, Rosenwasser-Weiss S, Ben-Yehuda G, Shefer HK, Friedman-Gohas M, Yassur I, Tauber G, Bejar J, Olshinka A, Vardizer Y, Ad El D, Goldenberg-Cohen N
Sci Rep 2020 Jan 27;10(1):1244. doi: 10.1038/s41598-020-58117-0. PMID: 31988301Free PMC Article
Brown L, David J, Skopit S
J Drugs Dermatol 2018 Mar 1;17(3):358-362. PMID: 29537455
Migden MR, Chang ALS, Dirix L, Stratigos AJ, Lear JT
Cancer Treat Rev 2018 Mar;64:1-10. Epub 2017 Dec 14 doi: 10.1016/j.ctrv.2017.12.009. PMID: 29407368
Puig S, Berrocal A
Clin Transl Oncol 2015 Jul;17(7):497-503. Epub 2015 Feb 3 doi: 10.1007/s12094-014-1272-9. PMID: 25643667Free PMC Article
Wollina U, Tchernev G
Wien Med Wochenschr 2013 Aug;163(15-16):347-53. Epub 2013 Apr 16 doi: 10.1007/s10354-013-0193-5. PMID: 23589318

Clinical prediction guides

Damsin T, Lebas E, Marchal N, Rorive A, Nikkels AF
Expert Rev Anticancer Ther 2022 Mar;22(3):243-248. Epub 2022 Feb 22 doi: 10.1080/14737140.2022.2043748. PMID: 35175882
Stratigos AJ, Sekulic A, Peris K, Bechter O, Prey S, Kaatz M, Lewis KD, Basset-Seguin N, Chang ALS, Dalle S, Orland AF, Licitra L, Robert C, Ulrich C, Hauschild A, Migden MR, Dummer R, Li S, Yoo SY, Mohan K, Coates E, Jankovic V, Fiaschi N, Okoye E, Bassukas ID, Loquai C, De Giorgi V, Eroglu Z, Gutzmer R, Ulrich J, Puig S, Seebach F, Thurston G, Weinreich DM, Yancopoulos GD, Lowy I, Bowler T, Fury MG
Lancet Oncol 2021 Jun;22(6):848-857. Epub 2021 May 14 doi: 10.1016/S1470-2045(21)00126-1. PMID: 34000246
Khoo AB, Ali FR, Lear JT
Curr Opin Oncol 2016 Mar;28(2):180-4. doi: 10.1097/CCO.0000000000000259. PMID: 26780190
Rudin CM
Clin Cancer Res 2012 Jun 15;18(12):3218-22. Epub 2012 Jun 7 doi: 10.1158/1078-0432.CCR-12-0568. PMID: 22679179Free PMC Article
Dlugosz A, Agrawal S, Kirkpatrick P
Nat Rev Drug Discov 2012 Jun 1;11(6):437-8. doi: 10.1038/nrd3753. PMID: 22653209Free PMC Article

Recent systematic reviews

Hooiveld-Noeken JS, Eggen AC, Rácz E, de Vries EGE, Reyners AKL, Jalving M
Crit Rev Oncol Hematol 2022 Dec;180:103855. Epub 2022 Oct 17 doi: 10.1016/j.critrevonc.2022.103855. PMID: 36257534
Patel A, Kim JS, Liss J, Howard L, Jung SH, Kheterpal M
Dermatol Ther 2021 Nov;34(6):e15172. Epub 2021 Oct 28 doi: 10.1111/dth.15172. PMID: 34676633
Jacobsen AA, Aldahan AS, Hughes OB, Shah VV, Strasswimmer J
JAMA Dermatol 2016 Jul 1;152(7):816-24. doi: 10.1001/jamadermatol.2016.0780. PMID: 27096888

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