U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Advanced Thyroid Gland Carcinoma

MedGen UID:
1762546
•Concept ID:
C5418597
•
Neoplastic Process

Definition

Thyroid gland carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum.
Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S
Thyroid 2017 Mar;27(3):315-389. doi: 10.1089/thy.2016.0457. PMID: 28056690
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Recent clinical studies

Etiology

Thyroid Cancer: A Review.
Boucai L, Zafereo M, Cabanillas ME
JAMA 2024 Feb 6;331(5):425-435. doi: 10.1001/jama.2023.26348. PMID: 38319329
Thyroid cancer.
Chen DW, Lang BHH, McLeod DSA, Newbold K, Haymart MR
Lancet 2023 May 6;401(10387):1531-1544. Epub 2023 Apr 3 doi: 10.1016/S0140-6736(23)00020-X. PMID: 37023783
Current Guidelines for Management of Medullary Thyroid Carcinoma.
Kim M, Kim BH
Endocrinol Metab (Seoul) 2021 Jun;36(3):514-524. Epub 2021 Jun 22 doi: 10.3803/EnM.2021.1082. PMID: 34154310Free PMC Article
Thyroid cancer, recent advances in diagnosis and therapy.
Nabhan F, Dedhia PH, Ringel MD
Int J Cancer 2021 Sep 1;149(5):984-992. Epub 2021 May 29 doi: 10.1002/ijc.33690. PMID: 34013533
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Diagnosis

Thyroid Cancer: A Review.
Boucai L, Zafereo M, Cabanillas ME
JAMA 2024 Feb 6;331(5):425-435. doi: 10.1001/jama.2023.26348. PMID: 38319329
Thyroid cancer.
Chen DW, Lang BHH, McLeod DSA, Newbold K, Haymart MR
Lancet 2023 May 6;401(10387):1531-1544. Epub 2023 Apr 3 doi: 10.1016/S0140-6736(23)00020-X. PMID: 37023783
Thyroid cancer, recent advances in diagnosis and therapy.
Nabhan F, Dedhia PH, Ringel MD
Int J Cancer 2021 Sep 1;149(5):984-992. Epub 2021 May 29 doi: 10.1002/ijc.33690. PMID: 34013533
Updates on the Management of Thyroid Cancer.
Araque KA, Gubbi S, Klubo-Gwiezdzinska J
Horm Metab Res 2020 Aug;52(8):562-577. Epub 2020 Feb 10 doi: 10.1055/a-1089-7870. PMID: 32040962Free PMC Article
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Therapy

Thyroid cancer.
Chen DW, Lang BHH, McLeod DSA, Newbold K, Haymart MR
Lancet 2023 May 6;401(10387):1531-1544. Epub 2023 Apr 3 doi: 10.1016/S0140-6736(23)00020-X. PMID: 37023783
Current Guidelines for Management of Medullary Thyroid Carcinoma.
Kim M, Kim BH
Endocrinol Metab (Seoul) 2021 Jun;36(3):514-524. Epub 2021 Jun 22 doi: 10.3803/EnM.2021.1082. PMID: 34154310Free PMC Article
Updates on the Management of Thyroid Cancer.
Araque KA, Gubbi S, Klubo-Gwiezdzinska J
Horm Metab Res 2020 Aug;52(8):562-577. Epub 2020 Feb 10 doi: 10.1055/a-1089-7870. PMID: 32040962Free PMC Article
DNA methylation in thyroid cancer.
Zafon C, Gil J, Pérez-González B, Jordà M
Endocr Relat Cancer 2019 Jul;26(7):R415-R439. doi: 10.1530/ERC-19-0093. PMID: 31035251
Thyroid cancer.
Carling T, Udelsman R
Annu Rev Med 2014;65:125-37. Epub 2013 Nov 20 doi: 10.1146/annurev-med-061512-105739. PMID: 24274180

Prognosis

Update on Molecular Diagnostics in Thyroid Pathology: A Review.
Alzumaili B, Sadow PM
Genes (Basel) 2023 Jun 22;14(7) doi: 10.3390/genes14071314. PMID: 37510219Free PMC Article
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
Thyroid Nodules: Advances in Evaluation and Management.
Kant R, Davis A, Verma V
Am Fam Physician 2020 Sep 1;102(5):298-304. PMID: 32866364
Poorly Differentiated Carcinoma of the Thyroid Gland: Current Status and Future Prospects.
Ibrahimpasic T, Ghossein R, Shah JP, Ganly I
Thyroid 2019 Mar;29(3):311-321. doi: 10.1089/thy.2018.0509. PMID: 30747050Free PMC Article
Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.
Rahib L, Smith BD, Aizenberg R, Rosenzweig AB, Fleshman JM, Matrisian LM
Cancer Res 2014 Jun 1;74(11):2913-21. doi: 10.1158/0008-5472.CAN-14-0155. PMID: 24840647

Clinical prediction guides

Thyroid Cancer: A Review.
Boucai L, Zafereo M, Cabanillas ME
JAMA 2024 Feb 6;331(5):425-435. doi: 10.1001/jama.2023.26348. PMID: 38319329
Radioiodine therapy in advanced differentiated thyroid cancer: Resistance and overcoming strategy.
Liu Y, Wang J, Hu X, Pan Z, Xu T, Xu J, Jiang L, Huang P, Zhang Y, Ge M
Drug Resist Updat 2023 May;68:100939. Epub 2023 Feb 8 doi: 10.1016/j.drup.2023.100939. PMID: 36806005
Contemporary Management of Thyroid Nodules.
Kobaly K, Kim CS, Mandel SJ
Annu Rev Med 2022 Jan 27;73:517-528. Epub 2021 Aug 20 doi: 10.1146/annurev-med-042220-015032. PMID: 34416120
Thyroid Nodules: Advances in Evaluation and Management.
Kant R, Davis A, Verma V
Am Fam Physician 2020 Sep 1;102(5):298-304. PMID: 32866364
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L
Thyroid 2016 Jan;26(1):1-133. doi: 10.1089/thy.2015.0020. PMID: 26462967Free PMC Article

Recent systematic reviews

Microbiota and Thyroid Disease: An Updated Systematic Review.
Stramazzo I, Capriello S, Filardo S, Centanni M, Virili C
Adv Exp Med Biol 2023;1370:125-144. doi: 10.1007/5584_2023_770. PMID: 36971966
Risk and Prognostic Factors for BRAF(V600E) Mutations in Papillary Thyroid Carcinoma.
Wei X, Wang X, Xiong J, Li C, Liao Y, Zhu Y, Mao J
Biomed Res Int 2022;2022:9959649. Epub 2022 May 18 doi: 10.1155/2022/9959649. PMID: 35647194Free PMC Article
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
A Systematic Review and Meta-Analysis of Endocrine-Related Adverse Events Associated with Immune Checkpoint Inhibitors.
de Filette J, Andreescu CE, Cools F, Bravenboer B, Velkeniers B
Horm Metab Res 2019 Mar;51(3):145-156. Epub 2019 Mar 12 doi: 10.1055/a-0843-3366. PMID: 30861560
Incidence of Endocrine Dysfunction Following the Use of Different Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-analysis.
Barroso-Sousa R, Barry WT, Garrido-Castro AC, Hodi FS, Min L, Krop IE, Tolaney SM
JAMA Oncol 2018 Feb 1;4(2):173-182. doi: 10.1001/jamaoncol.2017.3064. PMID: 28973656Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...