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Advanced Malignant Genitourinary System Neoplasm

MedGen UID:
1783465
Concept ID:
C5447477
Neoplastic Process

Definition

A malignant genitourinary neoplasm that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Malignant Genitourinary System Neoplasm

Professional guidelines

PubMed

Compérat E, Amin MB, Cathomas R, Choudhury A, De Santis M, Kamat A, Stenzl A, Thoeny HC, Witjes JA
Lancet 2022 Nov 12;400(10364):1712-1721. Epub 2022 Sep 26 doi: 10.1016/S0140-6736(22)01188-6. PMID: 36174585
Sekhoacha M, Riet K, Motloung P, Gumenku L, Adegoke A, Mashele S
Molecules 2022 Sep 5;27(17) doi: 10.3390/molecules27175730. PMID: 36080493Free PMC Article
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037

Recent clinical studies

Etiology

Lopez-Beltran A, Cookson MS, Guercio BJ, Cheng L
BMJ 2024 Feb 12;384:e076743. doi: 10.1136/bmj-2023-076743. PMID: 38346808
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Crosbie EJ, Kitson SJ, McAlpine JN, Mukhopadhyay A, Powell ME, Singh N
Lancet 2022 Apr 9;399(10333):1412-1428. doi: 10.1016/S0140-6736(22)00323-3. PMID: 35397864
Spreafico F, Fernandez CV, Brok J, Nakata K, Vujanic G, Geller JI, Gessler M, Maschietto M, Behjati S, Polanco A, Paintsil V, Luna-Fineman S, Pritchard-Jones K
Nat Rev Dis Primers 2021 Oct 14;7(1):75. doi: 10.1038/s41572-021-00308-8. PMID: 34650095
Teo MY, Rathkopf DE, Kantoff P
Annu Rev Med 2019 Jan 27;70:479-499. doi: 10.1146/annurev-med-051517-011947. PMID: 30691365Free PMC Article

Diagnosis

Konstantinopoulos PA, Matulonis UA
Nat Cancer 2023 Sep;4(9):1239-1257. Epub 2023 Aug 31 doi: 10.1038/s43018-023-00617-9. PMID: 37653142
Wasim S, Lee SY, Kim J
Int J Mol Sci 2022 Nov 17;23(22) doi: 10.3390/ijms232214257. PMID: 36430730Free PMC Article
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
Wang G, Zhao D, Spring DJ, DePinho RA
Genes Dev 2018 Sep 1;32(17-18):1105-1140. doi: 10.1101/gad.315739.118. PMID: 30181359Free PMC Article
Capitanio U, Montorsi F
Lancet 2016 Feb 27;387(10021):894-906. Epub 2015 Aug 25 doi: 10.1016/S0140-6736(15)00046-X. PMID: 26318520

Therapy

Bogani G, Monk BJ, Powell MA, Westin SN, Slomovitz B, Moore KN, Eskander RN, Raspagliesi F, Barretina-Ginesta MP, Colombo N, Mirza MR
Ann Oncol 2024 May;35(5):414-428. Epub 2024 Feb 29 doi: 10.1016/j.annonc.2024.02.006. PMID: 38431043
Jang A, Kendi AT, Johnson GB, Halfdanarson TR, Sartor O
Int J Mol Sci 2023 Jul 19;24(14) doi: 10.3390/ijms241411626. PMID: 37511386Free PMC Article
He Y, Xu W, Xiao YT, Huang H, Gu D, Ren S
Signal Transduct Target Ther 2022 Jun 24;7(1):198. doi: 10.1038/s41392-022-01042-7. PMID: 35750683Free PMC Article
Achard V, Putora PM, Omlin A, Zilli T, Fischer S
Oncology 2022;100(1):48-59. Epub 2021 Nov 15 doi: 10.1159/000519861. PMID: 34781285
Attademo L, Tuninetti V, Pisano C, Cecere SC, Di Napoli M, Tambaro R, Valabrega G, Musacchio L, Setola SV, Piccirillo P, Califano D, Spina A, Losito S, Greggi S, Pignata S
Cancer Treat Rev 2020 Nov;90:102088. Epub 2020 Aug 7 doi: 10.1016/j.ctrv.2020.102088. PMID: 32827839

Prognosis

Siegel RL, Miller KD, Fuchs HE, Jemal A
CA Cancer J Clin 2022 Jan;72(1):7-33. Epub 2022 Jan 12 doi: 10.3322/caac.21708. PMID: 35020204
O'Malley DM, Bariani GM, Cassier PA, Marabelle A, Hansen AR, De Jesus Acosta A, Miller WH Jr, Safra T, Italiano A, Mileshkin L, Xu L, Jin F, Norwood K, Maio M
J Clin Oncol 2022 Mar 1;40(7):752-761. Epub 2022 Jan 6 doi: 10.1200/JCO.21.01874. PMID: 34990208Free PMC Article
Castellino SM, McLean TW
Curr Opin Oncol 2007 May;19(3):248-53. doi: 10.1097/CCO.0b013e3280ad43ce. PMID: 17414644
Moore DH
Obstet Gynecol 2006 May;107(5):1152-61. doi: 10.1097/01.AOG.0000215986.48590.79. PMID: 16648423
Merguerian PA
Curr Opin Oncol 2003 May;15(3):222-6. doi: 10.1097/00001622-200305000-00008. PMID: 12778016

Clinical prediction guides

Jha AK, Mithun S, Sherkhane UB, Jaiswar V, Osong B, Purandare N, Kannan S, Prabhash K, Gupta S, Vanneste B, Rangarajan V, Dekker A, Wee L
Artif Intell Med 2023 May;139:102549. Epub 2023 Apr 11 doi: 10.1016/j.artmed.2023.102549. PMID: 37100501
Derosa L, Routy B, Fidelle M, Iebba V, Alla L, Pasolli E, Segata N, Desnoyer A, Pietrantonio F, Ferrere G, Fahrner JE, Le Chatellier E, Pons N, Galleron N, Roume H, Duong CPM, Mondragón L, Iribarren K, Bonvalet M, Terrisse S, Rauber C, Goubet AG, Daillère R, Lemaitre F, Reni A, Casu B, Alou MT, Alves Costa Silva C, Raoult D, Fizazi K, Escudier B, Kroemer G, Albiges L, Zitvogel L
Eur Urol 2020 Aug;78(2):195-206. Epub 2020 May 4 doi: 10.1016/j.eururo.2020.04.044. PMID: 32376136
Jones RT, Felsenstein KM, Theodorescu D
Urol Clin North Am 2016 Feb;43(1):77-86. Epub 2015 Oct 31 doi: 10.1016/j.ucl.2015.08.007. PMID: 26614030Free PMC Article
Van Calster B, Van Hoorde K, Valentin L, Testa AC, Fischerova D, Van Holsbeke C, Savelli L, Franchi D, Epstein E, Kaijser J, Van Belle V, Czekierdowski A, Guerriero S, Fruscio R, Lanzani C, Scala F, Bourne T, Timmerman D; International Ovarian Tumour Analysis Group
BMJ 2014 Oct 15;349:g5920. doi: 10.1136/bmj.g5920. PMID: 25320247Free PMC Article
Merguerian PA
Curr Opin Oncol 2003 May;15(3):222-6. doi: 10.1097/00001622-200305000-00008. PMID: 12778016

Recent systematic reviews

Siva S, Louie AV, Kotecha R, Barber MN, Ali M, Zhang Z, Guckenberger M, Kim MS, Scorsetti M, Tree AC, Slotman BJ, Sahgal A, Lo SS
Lancet Oncol 2024 Jan;25(1):e18-e28. doi: 10.1016/S1470-2045(23)00513-2. PMID: 38181809
Jha AK, Mithun S, Sherkhane UB, Jaiswar V, Osong B, Purandare N, Kannan S, Prabhash K, Gupta S, Vanneste B, Rangarajan V, Dekker A, Wee L
Artif Intell Med 2023 May;139:102549. Epub 2023 Apr 11 doi: 10.1016/j.artmed.2023.102549. PMID: 37100501
Bukavina L, Bensalah K, Bray F, Carlo M, Challacombe B, Karam JA, Kassouf W, Mitchell T, Montironi R, O'Brien T, Panebianco V, Scelo G, Shuch B, van Poppel H, Blosser CD, Psutka SP
Eur Urol 2022 Nov;82(5):529-542. Epub 2022 Sep 10 doi: 10.1016/j.eururo.2022.08.019. PMID: 36100483
Vale CL, Fisher D, Kneebone A, Parker C, Pearse M, Richaud P, Sargos P, Sydes MR, Brawley C, Brihoum M, Brown C, Chabaud S, Cook A, Forcat S, Fraser-Browne C, Latorzeff I, Parmar MKB, Tierney JF; ARTISTIC Meta-analysis Group
Lancet 2020 Oct 31;396(10260):1422-1431. Epub 2020 Sep 28 doi: 10.1016/S0140-6736(20)31952-8. PMID: 33002431Free PMC Article
Peirson L, Fitzpatrick-Lewis D, Ciliska D, Warren R
Syst Rev 2013 May 24;2:35. doi: 10.1186/2046-4053-2-35. PMID: 23706117Free PMC Article

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