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Asperger syndrome, susceptibility to

MedGen UID:
1800816
Concept ID:
CN078133
Disease or Syndrome
Monarch Initiative: MONDO:0100440
OMIM® Phenotypic series: PS608638

Definition

An inherited susceptibility or predisposition to developing Asperger sydrome. [from MONDO]

Professional guidelines

PubMed

Taurines R, Schwenck C, Westerwald E, Sachse M, Siniatchkin M, Freitag C
Atten Defic Hyperact Disord 2012 Sep;4(3):115-39. Epub 2012 Aug 1 doi: 10.1007/s12402-012-0086-2. PMID: 22851255

Recent clinical studies

Etiology

Cruz ACP, Ferrasa A, Muotri AR, Herai RH
Mitochondrion 2019 May;46:345-360. Epub 2018 Sep 13 doi: 10.1016/j.mito.2018.09.005. PMID: 30218715
Taurines R, Schwenck C, Westerwald E, Sachse M, Siniatchkin M, Freitag C
Atten Defic Hyperact Disord 2012 Sep;4(3):115-39. Epub 2012 Aug 1 doi: 10.1007/s12402-012-0086-2. PMID: 22851255
Telford C, McCarthy-Jones S, Corcoran R, Rowse G
Psychol Med 2012 Jun;42(6):1119-29. Epub 2011 Oct 19 doi: 10.1017/S0033291711002200. PMID: 22008511
Bourgeron T
Curr Opin Neurobiol 2009 Apr;19(2):231-4. Epub 2009 Jun 21 doi: 10.1016/j.conb.2009.06.003. PMID: 19545994
Santangelo SL, Tsatsanis K
Am J Pharmacogenomics 2005;5(2):71-92. doi: 10.2165/00129785-200505020-00001. PMID: 15813671

Diagnosis

Taurines R, Schwenck C, Westerwald E, Sachse M, Siniatchkin M, Freitag C
Atten Defic Hyperact Disord 2012 Sep;4(3):115-39. Epub 2012 Aug 1 doi: 10.1007/s12402-012-0086-2. PMID: 22851255
Bourgeron T
Curr Opin Neurobiol 2009 Apr;19(2):231-4. Epub 2009 Jun 21 doi: 10.1016/j.conb.2009.06.003. PMID: 19545994
Gillberg C, Billstedt E
Acta Psychiatr Scand 2000 Nov;102(5):321-30. doi: 10.1034/j.1600-0447.2000.102005321.x. PMID: 11098802
Ropar D, Mitchell P
J Child Psychol Psychiatry 1999 Nov;40(8):1283-93. PMID: 10604406
Charman T
Curr Opin Neurol 1999 Apr;12(2):155-9. doi: 10.1097/00019052-199904000-00005. PMID: 10226747

Therapy

Taurines R, Schwenck C, Westerwald E, Sachse M, Siniatchkin M, Freitag C
Atten Defic Hyperact Disord 2012 Sep;4(3):115-39. Epub 2012 Aug 1 doi: 10.1007/s12402-012-0086-2. PMID: 22851255
Telford C, McCarthy-Jones S, Corcoran R, Rowse G
Psychol Med 2012 Jun;42(6):1119-29. Epub 2011 Oct 19 doi: 10.1017/S0033291711002200. PMID: 22008511
Inglese MD, Elder JH
J Pediatr Nurs 2009 Feb;24(1):41-8. Epub 2008 Jun 13 doi: 10.1016/j.pedn.2007.12.006. PMID: 19159834
Wing L, Potter D
Ment Retard Dev Disabil Res Rev 2002;8(3):151-61. doi: 10.1002/mrdd.10029. PMID: 12216059

Prognosis

Jokiranta-Olkoniemi E, Cheslack-Postava K, Sucksdorff D, Suominen A, Gyllenberg D, Chudal R, Leivonen S, Gissler M, Brown AS, Sourander A
JAMA Psychiatry 2016 Jun 1;73(6):622-9. doi: 10.1001/jamapsychiatry.2016.0495. PMID: 27145529
Telford C, McCarthy-Jones S, Corcoran R, Rowse G
Psychol Med 2012 Jun;42(6):1119-29. Epub 2011 Oct 19 doi: 10.1017/S0033291711002200. PMID: 22008511
Orsmond GI, Seltzer MM
Ment Retard Dev Disabil Res Rev 2007;13(4):313-20. doi: 10.1002/mrdd.20171. PMID: 17979200
Wing L, Potter D
Ment Retard Dev Disabil Res Rev 2002;8(3):151-61. doi: 10.1002/mrdd.10029. PMID: 12216059
Ropar D, Mitchell P
J Child Psychol Psychiatry 2001 May;42(4):539-49. PMID: 11383970

Clinical prediction guides

Curie A, Lesca G, Bussy G, Manificat S, Arnaud V, Gonzalez S, Revol O, Calender A, Gérard D, des Portes V
Psychiatr Genet 2017 Jun;27(3):105-109. doi: 10.1097/YPG.0000000000000165. PMID: 28230711
Jokiranta-Olkoniemi E, Cheslack-Postava K, Sucksdorff D, Suominen A, Gyllenberg D, Chudal R, Leivonen S, Gissler M, Brown AS, Sourander A
JAMA Psychiatry 2016 Jun 1;73(6):622-9. doi: 10.1001/jamapsychiatry.2016.0495. PMID: 27145529
Telford C, McCarthy-Jones S, Corcoran R, Rowse G
Psychol Med 2012 Jun;42(6):1119-29. Epub 2011 Oct 19 doi: 10.1017/S0033291711002200. PMID: 22008511
Kilpinen H, Ylisaukko-Oja T, Hennah W, Palo OM, Varilo T, Vanhala R, Nieminen-von Wendt T, von Wendt L, Paunio T, Peltonen L
Mol Psychiatry 2008 Feb;13(2):187-96. Epub 2007 Jun 19 doi: 10.1038/sj.mp.4002031. PMID: 17579608
Ingram JL, Stodgell CJ, Hyman SL, Figlewicz DA, Weitkamp LR, Rodier PM
Teratology 2000 Dec;62(6):393-405. doi: 10.1002/1096-9926(200012)62:6<393::AID-TERA6>3.0.CO;2-V. PMID: 11091361

Recent systematic reviews

Cruz ACP, Ferrasa A, Muotri AR, Herai RH
Mitochondrion 2019 May;46:345-360. Epub 2018 Sep 13 doi: 10.1016/j.mito.2018.09.005. PMID: 30218715

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