Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Developmental disorder

MedGen UID:: 3367
•Concept ID:: C0008073
•: Mental or Behavioral Dysfunction

Synonyms:	Child Development Disorder; Child Development Disorders; Development Disorder, Child; Development Disorders, Child; Developmental Disabilities; Developmental Disability; Disabilities, Developmental; Disability, Developmental
SNOMED CT:	Developmental disorder (5294002)

Definition

A disorder diagnosed in childhood that is marked by either physical or mental impairment or both, which in turn affects the child from achieving age related developmental milestones. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

Developmental disorder

Developmental disorder
- Neurodevelopmental disorder
  - Developmental disorder
    - Neurodevelopmental disorder
      - Developmental disorder
        Neurodevelopmental disorder
        Developmental disorder
        Developmental coordination disorder
        Developmental delay
        Motor delay
        Delayed fine motor development
        Delayed gross motor development
        fine motor delay
        Persistent head lag
        Developmental regression
        Cognitive regression
        Motor regression
        Mental Retardation
        ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder
        Alpha thalassemia-X-linked intellectual disability syndrome
        Borjeson-Forssman-Lehmann syndrome
        Christianson syndrome
        Intellectual disability, autosomal dominant 1
        Intellectual disability, autosomal dominant 5
        Intellectual disability, autosomal dominant 39
        Intellectual disability, autosomal recessive 34
        Intellectual disability, X-linked 1
        Mental Retardation, Autosomal Dominant 40
        Mental Retardation, X-linked 102
        Mental Retardation, X-linked 21/34
        Renpenning syndrome
        Hamel cerebro-palato-cardiac syndrome
        X-linked intellectual disability, Golabi-Ito-hall type
        X-linked intellectual disability, Porteous type
        X-linked intellectual disability, Sutherland-Haan type
        Severe intellectual disability-progressive spastic diplegia syndrome
        Syndromic X-linked intellectual disability Lubs type
        X-linked intellectual disability Cabezas type
        Naevus Lipomatosus Superficialis
        Neurodevelopmental disorder
        Attention Deficit and Disruptive Behavior Disorders
        Attention deficit hyperactivity disorder
        conduct disorder
        Sluggish Cognitive Tempo
        Brain Development Abnormality
        Abnormality of neuronal migration
        Hydranencephaly
        Isolated congenital microcephaly
        microgyria
        Pontocerebellar hypoplasia type 2
        Subcortical band heterotopia
        Child Behavior Disorders
        Child Development Disorders, Pervasive
        Autism spectrum disorder
        Childhood-onset schizophrenia
        communication disorder
        Abnormality of speech or vocalization
        Childhood onset fluency disorder
        Impaired social interactions
        Language disorder
        Learning disability
        Speech-sound disorder
        Congenital meningocele
        Congenital cerebral meningocele
        Congenital spinal meningocele
        Fetal Neurodevelopmental Disorder
        Gabriele de Vries syndrome
        Intellectual disability
        11p partial monosomy syndrome
        5p partial monosomy syndrome
        Complete trisomy 21 syndrome
        De Lange syndrome
        Intellectual disability, borderline
        Intellectual disability, mild
        Intellectual disability, moderate
        Intellectual disability, profound
        Intellectual disability, progressive
        Intellectual disability, severe
        Prader-Willi syndrome
        Rubinstein-Taybi syndrome
        Trisomy 13 Syndromes
        Williams syndrome
        X-linked intellectual disability
        Motor skill disorder
        Mutism
        Selective mutism
        Myelocele
        Cervical myelocele
        Lumbar myelocele
        Sacral Myelocele
        Thoracic myelocele
        reactive attachment disorder
        Separation anxiety disorder
        Stereotypic movement disorder
        Tic
        Tourette syndrome
        Reactive Attachment Disorder of Infancy or Early Childhood

Professional guidelines

PubMed

Overview of the Recent Advances in Pathophysiology and Treatment for Autism.

Famitafreshi H, Karimian M
CNS Neurol Disord Drug Targets 2018;17(8):590-594. doi: 10.2174/1871527317666180706141654. PMID: 29984672

Autism Spectrum Disorders - Diagnosis and Management.

Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829

Autism Spectrum Disorder: Primary Care Principles.

Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089

See all (138)

Recent clinical studies

Etiology

Food Selectivity and Its Implications Associated with Gastrointestinal Disorders in Children with Autism Spectrum Disorders.

Valenzuela-Zamora AF, Ramírez-Valenzuela DG, Ramos-Jiménez A
Nutrients 2022 Jun 27;14(13) doi: 10.3390/nu14132660. PMID: 35807840 Free PMC Article

Autism Spectrum Disorder: Classification, diagnosis and therapy.

Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648

Autism Spectrum Disorders - Diagnosis and Management.

Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829

Autism and related disorders.

McPartland J, Volkmar FR
Handb Clin Neurol 2012;106:407-18. doi: 10.1016/B978-0-444-52002-9.00023-1. PMID: 22608634 Free PMC Article

Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.

Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, Walker-Smith JA
Lancet 1998 Feb 28;351(9103):637-41. doi: 10.1016/s0140-6736(97)11096-0. PMID: 9500320

See all (1343)

Diagnosis

Current thinking in the health care management of children with cerebral palsy.

Graham D, Paget SP, Wimalasundera N
Med J Aust 2019 Feb;210(3):129-135. Epub 2019 Feb 10 doi: 10.5694/mja2.12106. PMID: 30739332

Autism Spectrum Disorder: Classification, diagnosis and therapy.

Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648

Leo Kanner and autism: a 75-year perspective.

Harris J
Int Rev Psychiatry 2018 Feb;30(1):3-17. Epub 2018 Apr 18 doi: 10.1080/09540261.2018.1455646. PMID: 29667863

Autism Spectrum Disorders - Diagnosis and Management.

Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829

Autism and related disorders.

McPartland J, Volkmar FR
Handb Clin Neurol 2012;106:407-18. doi: 10.1016/B978-0-444-52002-9.00023-1. PMID: 22608634 Free PMC Article

See all (1734)

Therapy

Autism Spectrum Disorder: Classification, diagnosis and therapy.

Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648

Attention-Deficit/Hyperactivity Disorder.

Banaschewski T, Becker K, Döpfner M, Holtmann M, Rösler M, Romanos M
Dtsch Arztebl Int 2017 Mar 3;114(9):149-159. doi: 10.3238/arztebl.2017.0149. PMID: 28351467 Free PMC Article

Autism Spectrum Disorder: Primary Care Principles.

Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089

Pesticide exposure in children.

Roberts JR, Karr CJ; Council On Environmental Health
Pediatrics 2012 Dec;130(6):e1765-88. Epub 2012 Nov 26 doi: 10.1542/peds.2012-2758. PMID: 23184105 Free PMC Article

Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.

See all (442)

Prognosis

Autism: an 'epidemic' of contemporary times?

de Araujo CA
J Anal Psychol 2022 Feb;67(1):5-20. doi: 10.1111/1468-5922.12746. PMID: 35417594

Attention-Deficit/Hyperactivity Disorder.

Banaschewski T, Becker K, Döpfner M, Holtmann M, Rösler M, Romanos M
Dtsch Arztebl Int 2017 Mar 3;114(9):149-159. doi: 10.3238/arztebl.2017.0149. PMID: 28351467 Free PMC Article

Autism Spectrum Disorder: Primary Care Principles.

Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089

The Cerebellum and Neurodevelopmental Disorders.

Stoodley CJ
Cerebellum 2016 Feb;15(1):34-37. doi: 10.1007/s12311-015-0715-3. PMID: 26298473 Free PMC Article

A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes.

Sagvolden T, Johansen EB, Aase H, Russell VA
Behav Brain Sci 2005 Jun;28(3):397-419; discussion 419-68. doi: 10.1017/S0140525X05000075. PMID: 16209748

See all (548)

Clinical prediction guides

Food Selectivity and Its Implications Associated with Gastrointestinal Disorders in Children with Autism Spectrum Disorders.

Valenzuela-Zamora AF, Ramírez-Valenzuela DG, Ramos-Jiménez A
Nutrients 2022 Jun 27;14(13) doi: 10.3390/nu14132660. PMID: 35807840 Free PMC Article

Autism Spectrum Disorder: Classification, diagnosis and therapy.

Sharma SR, Gonda X, Tarazi FI
Pharmacol Ther 2018 Oct;190:91-104. Epub 2018 May 12 doi: 10.1016/j.pharmthera.2018.05.007. PMID: 29763648

Autism Spectrum Disorders - Diagnosis and Management.

Mukherjee SB
Indian J Pediatr 2017 Apr;84(4):307-314. Epub 2017 Jan 19 doi: 10.1007/s12098-016-2272-2. PMID: 28101829

The Cerebellum and Neurodevelopmental Disorders.

Stoodley CJ
Cerebellum 2016 Feb;15(1):34-37. doi: 10.1007/s12311-015-0715-3. PMID: 26298473 Free PMC Article

microRNA and Autism.

Anitha A, Thanseem I
Adv Exp Med Biol 2015;888:71-83. doi: 10.1007/978-3-319-22671-2_5. PMID: 26663179

See all (981)

Recent systematic reviews

Global prevalence of intellectual developmental disorder in dystrophinopathies: A systematic review and meta-analysis.

Pascual-Morena C, Cavero-Redondo I, Álvarez-Bueno C, Jiménez-López E, Saz-Lara A, Martínez-García I, Martínez-Vizcaíno V
Dev Med Child Neurol 2023 Jun;65(6):734-744. Epub 2022 Nov 28 doi: 10.1111/dmcn.15481. PMID: 36440509

Oral Manifestations of Rett Syndrome-A Systematic Review.

Mahdi SS, Jafri HA, Allana R, Amenta F, Khawaja M, Qasim SSB
Int J Environ Res Public Health 2021 Jan 28;18(3) doi: 10.3390/ijerph18031162. PMID: 33525609 Free PMC Article

Practitioner Review: Pharmacological treatment of attention-deficit/hyperactivity disorder symptoms in children and youth with autism spectrum disorder: a systematic review and meta-analysis.

Rodrigues R, Lai MC, Beswick A, Gorman DA, Anagnostou E, Szatmari P, Anderson KK, Ameis SH
J Child Psychol Psychiatry 2021 Jun;62(6):680-700. Epub 2020 Aug 26 doi: 10.1111/jcpp.13305. PMID: 32845025

Non-pharmacological interventions for adult ADHD: a systematic review.

Nimmo-Smith V, Merwood A, Hank D, Brandling J, Greenwood R, Skinner L, Law S, Patel V, Rai D
Psychol Med 2020 Mar;50(4):529-541. Epub 2020 Feb 10 doi: 10.1017/S0033291720000069. PMID: 32036811

The role of phthalate esters in autism development: A systematic review.

Jeddi MZ, Janani L, Memari AH, Akhondzadeh S, Yunesian M
Environ Res 2016 Nov;151:493-504. Epub 2016 Aug 24 doi: 10.1016/j.envres.2016.08.021. PMID: 27567353

See all (49)

MedGen

National Center for Biotechnology Information

Send to:

Developmental disorder

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

Related information

Recent activity