U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Urethral Infection

MedGen UID:
182685
•Concept ID:
C0948357
•
Disease or Syndrome

Definition

A bacterial, viral, or fungal infectious process affecting the urethra. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrethral Infection

Professional guidelines

PubMed

Management of urethral atrophy after implantation of artificial urinary sphincter: what are the weaknesses?
Heah NH, Tan RBW
Asian J Androl 2020 Jan-Feb;22(1):60-63. doi: 10.4103/aja.aja_110_19. PMID: 31736473Free PMC Article
Differential diagnosis of chronic pelvic pain in women: the urologist's approach.
Fletcher SG, Zimmern PE
Nat Rev Urol 2009 Oct;6(10):557-62. Epub 2009 Sep 1 doi: 10.1038/nrurol.2009.178. PMID: 19724247
Catheterization: possible complications and their prevention and treatment.
Igawa Y, Wyndaele JJ, Nishizawa O
Int J Urol 2008 Jun;15(6):481-5. Epub 2008 Apr 22 doi: 10.1111/j.1442-2042.2008.02075.x. PMID: 18430150

Recent clinical studies

Etiology

Comparison of the patterns of chlamydia and gonorrhoea at the oropharynx, anorectum and urethra among men who have sex with men.
Tabesh M, Fairley CK, Hocking JS, Williamson DA, Zhang L, Xu X, Bradshaw CS, Chen MY, Chow EP
Sex Transm Infect 2022 Feb;98(1):11-16. Epub 2021 Jan 12 doi: 10.1136/sextrans-2020-054632. PMID: 33436503
Epidemiological, clinical and laboratory differences between male urethral infections due to Haemophilus spp. and those due to Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum: A descriptive study.
Vives A, Cosentino M, Bassas L, Alonso C, Millan F
Arch Ital Urol Androl 2021 Dec 21;93(4):468-474. doi: 10.4081/aiua.2021.4.468. PMID: 34933533
The prevalence of urethral and rectal Mycoplasma genitalium and its associations in men who have sex with men attending a genitourinary medicine clinic.
Soni S, Alexander S, Verlander N, Saunders P, Richardson D, Fisher M, Ison C
Sex Transm Infect 2010 Feb;86(1):21-4. Epub 2009 Oct 19 doi: 10.1136/sti.2009.038190. PMID: 19843536
The prevalence of genital Chlamydia trachomatis in Australia 1997-2004: a systematic review.
Vajdic CM, Middleton M, Bowden FJ, Fairley CK, Kaldor JM
Sex Health 2005;2(3):169-83. doi: 10.1071/sh05018. PMID: 16335545
Chlamydia trachomatis screening in family planning centers: a review of cost/benefit evaluations in different countries.
Henry-Suchet J, Sluzhinska A, Serfaty D
Eur J Contracept Reprod Health Care 1996 Dec;1(4):301-9. doi: 10.3109/13625189609150675. PMID: 9678112

Diagnosis

Epidemiological, clinical and laboratory differences between male urethral infections due to Haemophilus spp. and those due to Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum: A descriptive study.
Vives A, Cosentino M, Bassas L, Alonso C, Millan F
Arch Ital Urol Androl 2021 Dec 21;93(4):468-474. doi: 10.4081/aiua.2021.4.468. PMID: 34933533
Modelling the in-host dynamics of Neisseria gonorrhoeae infection.
Jayasundara P, Regan DG, Seib KL, Jayasundara D, Wood JG
Pathog Dis 2019 Feb 1;77(1) doi: 10.1093/femspd/ftz008. PMID: 30770529
The prevalence of genital Chlamydia trachomatis in Australia 1997-2004: a systematic review.
Vajdic CM, Middleton M, Bowden FJ, Fairley CK, Kaldor JM
Sex Health 2005;2(3):169-83. doi: 10.1071/sh05018. PMID: 16335545
Pathophysiology of priapism: dysregulatory erection physiology thesis.
Burnett AL
J Urol 2003 Jul;170(1):26-34. doi: 10.1097/01.ju.0000046303.22757.f2. PMID: 12796638
Chlamydia trachomatis screening in family planning centers: a review of cost/benefit evaluations in different countries.
Henry-Suchet J, Sluzhinska A, Serfaty D
Eur J Contracept Reprod Health Care 1996 Dec;1(4):301-9. doi: 10.3109/13625189609150675. PMID: 9678112

Therapy

Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.
Waltmann A, Balthazar JT, Begum AA, Hua N, Jerse AE, Shafer WM, Hobbs MM, Duncan JA
PLoS Pathog 2024 Sep;20(9):e1012578. Epub 2024 Sep 25 doi: 10.1371/journal.ppat.1012578. PMID: 39321205Free PMC Article
Prevalence of Mycoplasma genitalium and macrolide resistance in rectal and urine samples among men who have sex with men in Sweden.
Bjartling C, Kertes R, Kristiansen S, Johnsson A, Forslund O
Sex Transm Infect 2024 Oct 17;100(7):430-434. doi: 10.1136/sextrans-2023-056044. PMID: 39089883Free PMC Article
New Approach to Microscopy of Gram-Stained Urethral Smear: The Kissing Slide Method.
Sarier M, Demir M, Turgut H, Hizel A, Emek M, Kukul E, Sepin N
Sex Transm Dis 2020 Oct;47(10):712-715. doi: 10.1097/OLQ.0000000000001228. PMID: 32649578
Neisserial colonisation of the pharynx.
Young H, Bain SS
Br J Vener Dis 1983 Aug;59(4):228-31. doi: 10.1136/sti.59.4.228. PMID: 6409342Free PMC Article
Nongonococcal urethritis.
Handsfield HH
Cutis 1981 Mar;27(3):268-70, 275-7. PMID: 7214998

Prognosis

Experimental Urethral Infection with Neisseria gonorrhoeae.
Waltmann A, Duncan JA, Pier GB, Cywes-Bentley C, Cohen MS, Hobbs MM
Curr Top Microbiol Immunol 2024;445:109-125. doi: 10.1007/82_2021_250. PMID: 35246736Free PMC Article
Effect of nucleic acid amplification testing on detection of extragenital gonorrhea and chlamydial infections in men who have sex with men sexually transmitted disease clinic patients.
Barbee LA, Dombrowski JC, Kerani R, Golden MR
Sex Transm Dis 2014 Mar;41(3):168-72. doi: 10.1097/OLQ.0000000000000093. PMID: 24521722
Urethral infection in a workplace population of East African men: evaluation of strategies for screening and management.
Jackson DJ, Rakwar JP, Chohan B, Mandaliya K, Bwayo JJ, Ndinya-Achola JO, Nagelkerke NJ, Kreiss JK, Moses S
J Infect Dis 1997 Apr;175(4):833-8. doi: 10.1086/513979. PMID: 9086138
Screening for urethral infection in adolescent and young adult males.
Johnson J, Neas B, Parker DE, Fortenberry JD, Cowan LD
J Adolesc Health 1993 Jul;14(5):356-61. doi: 10.1016/s1054-139x(08)80007-9. PMID: 8399246
Diagnosis of Chlamydia trachomatis urethritis in men by polymerase chain reaction assay of first-catch urine.
Bauwens JE, Clark AM, Loeffelholz MJ, Herman SA, Stamm WE
J Clin Microbiol 1993 Nov;31(11):3013-6. doi: 10.1128/jcm.31.11.3013-3016.1993. PMID: 8263188Free PMC Article

Clinical prediction guides

High HIV/STI prevalence among cisgender men and transgender women sex workers attending community-based centres in Barcelona, Spain: The Sweetie Project.
Ferrer L, González V, Martró E, Folch C, Saludes V, Muñoz R, Rodríguez V, Morales A, Meroño M, Morey F, Sanjosé S, Casabona J
Int J STD AIDS 2022 Oct;33(12):1045-1053. Epub 2022 Sep 15 doi: 10.1177/09564624221116536. PMID: 36113447
First-Void Urine Microbiome in Women with Chlamydia trachomatis Infection.
Gaspari V, Ceccarani C, Severgnini M, Orioni G, Camboni T, Laghi L, Morselli S, Foschi C, Marangoni A, Consolandi C, Piraccini BM
Int J Mol Sci 2022 May 17;23(10) doi: 10.3390/ijms23105625. PMID: 35628436Free PMC Article
Epidemiological, clinical and laboratory differences between male urethral infections due to Haemophilus spp. and those due to Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum: A descriptive study.
Vives A, Cosentino M, Bassas L, Alonso C, Millan F
Arch Ital Urol Androl 2021 Dec 21;93(4):468-474. doi: 10.4081/aiua.2021.4.468. PMID: 34933533
Modelling the in-host dynamics of Neisseria gonorrhoeae infection.
Jayasundara P, Regan DG, Seib KL, Jayasundara D, Wood JG
Pathog Dis 2019 Feb 1;77(1) doi: 10.1093/femspd/ftz008. PMID: 30770529
Pathophysiology of priapism: dysregulatory erection physiology thesis.
Burnett AL
J Urol 2003 Jul;170(1):26-34. doi: 10.1097/01.ju.0000046303.22757.f2. PMID: 12796638

Recent systematic reviews

The prevalence of genital Chlamydia trachomatis in Australia 1997-2004: a systematic review.
Vajdic CM, Middleton M, Bowden FJ, Fairley CK, Kaldor JM
Sex Health 2005;2(3):169-83. doi: 10.1071/sh05018. PMID: 16335545

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...