U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dense granule disease

MedGen UID:
1842467
•Concept ID:
C5680362
•
Disease or Syndrome
Synonym: Delta granule disease
 
Orphanet: ORPHA98456

Professional guidelines

PubMed

Predictors of Response to Treatment with First-Generation Somatostatin Receptor Ligands in Patients with Acromegaly.
Marques-Pamies M, Gil J, Jordà M, Puig-Domingo M
Arch Med Res 2023 Dec;54(8):102924. Epub 2023 Dec 1 doi: 10.1016/j.arcmed.2023.102924. PMID: 38042683
Clinical, hormonal and pathomorphological markers of somatotroph pituitary neuroendocrine tumors predicting the treatment outcome in acromegaly.
Tomasik A, Stelmachowska-Banaś M, Maksymowicz M, Czajka-Oraniec I, Raczkiewicz D, Zieliński G, Kunicki J, Zgliczyński W
Front Endocrinol (Lausanne) 2022;13:957301. Epub 2022 Sep 16 doi: 10.3389/fendo.2022.957301. PMID: 36187106Free PMC Article
Neuroendocrine Tumors of the Esophagus: State of the Art in Diagnostic and Therapeutic Management.
Schizas D, Mastoraki A, Kirkilesis GI, Sioulas AD, Papanikolaou IS, Misiakos EP, Arkadopoulos N, Liakakos T
J Gastrointest Cancer 2017 Dec;48(4):299-304. doi: 10.1007/s12029-017-9978-x. PMID: 28656561

Recent clinical studies

Etiology

Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report.
Witkowski M, Wilcox J, Province V, Wang Z, Nemet I, Tang WHW, Hazen SL
Arterioscler Thromb Vasc Biol 2024 Sep;44(9):2136-2141. Epub 2024 Aug 8 doi: 10.1161/ATVBAHA.124.321019. PMID: 39114916Free PMC Article
Natural history study of patients with familial platelet disorder with associated myeloid malignancy.
Cunningham L, Merguerian M, Calvo KR, Davis J, Deuitch NT, Dulau-Florea A, Patel N, Yu K, Sacco K, Bhattacharya S, Passi M, Ozkaya N, De Leon S, Chong S, Craft K, Diemer J, Bresciani E, O'Brien K, Andrews EJ, Park N, Hathaway L, Cowen EW, Heller T, Ryan K, Barochia A, Nghiem K, Niemela J, Rosenzweig S, Young DJ, Frischmeyer-Guerrerio PA, Braylan R, Liu PP
Blood 2023 Dec 21;142(25):2146-2158. doi: 10.1182/blood.2023019746. PMID: 37738626Free PMC Article
Platelet-cancer interactions.
Goubran HA, Stakiw J, Radosevic M, Burnouf T
Semin Thromb Hemost 2014 Apr;40(3):296-305. Epub 2014 Mar 3 doi: 10.1055/s-0034-1370767. PMID: 24590421
Abdominal actinomycosis.
Garner JP, Macdonald M, Kumar PK
Int J Surg 2007 Dec;5(6):441-8. Epub 2006 Aug 10 doi: 10.1016/j.ijsu.2006.06.009. PMID: 18078685
Lysosome-related organelles.
Dell'Angelica EC, Mullins C, Caplan S, Bonifacino JS
FASEB J 2000 Jul;14(10):1265-78. doi: 10.1096/fj.14.10.1265. PMID: 10877819

Diagnosis

Natural history study of patients with familial platelet disorder with associated myeloid malignancy.
Cunningham L, Merguerian M, Calvo KR, Davis J, Deuitch NT, Dulau-Florea A, Patel N, Yu K, Sacco K, Bhattacharya S, Passi M, Ozkaya N, De Leon S, Chong S, Craft K, Diemer J, Bresciani E, O'Brien K, Andrews EJ, Park N, Hathaway L, Cowen EW, Heller T, Ryan K, Barochia A, Nghiem K, Niemela J, Rosenzweig S, Young DJ, Frischmeyer-Guerrerio PA, Braylan R, Liu PP
Blood 2023 Dec 21;142(25):2146-2158. doi: 10.1182/blood.2023019746. PMID: 37738626Free PMC Article
Lysosomal Trafficking Regulator (LYST).
Ji X, Chang B, Naggert JK, Nishina PM
Adv Exp Med Biol 2016;854:745-50. doi: 10.1007/978-3-319-17121-0_99. PMID: 26427484
Chromogranin A and the tumor microenvironment.
Corti A
Cell Mol Neurobiol 2010 Nov;30(8):1163-70. Epub 2010 Nov 16 doi: 10.1007/s10571-010-9587-8. PMID: 21080056
CADASIL.
Hervé D, Chabriat H
J Geriatr Psychiatry Neurol 2010 Dec;23(4):269-76. doi: 10.1177/0891988710383570. PMID: 21045164
Abdominal actinomycosis.
Garner JP, Macdonald M, Kumar PK
Int J Surg 2007 Dec;5(6):441-8. Epub 2006 Aug 10 doi: 10.1016/j.ijsu.2006.06.009. PMID: 18078685

Therapy

Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report.
Witkowski M, Wilcox J, Province V, Wang Z, Nemet I, Tang WHW, Hazen SL
Arterioscler Thromb Vasc Biol 2024 Sep;44(9):2136-2141. Epub 2024 Aug 8 doi: 10.1161/ATVBAHA.124.321019. PMID: 39114916Free PMC Article
Predictors of Response to Treatment with First-Generation Somatostatin Receptor Ligands in Patients with Acromegaly.
Marques-Pamies M, Gil J, Jordà M, Puig-Domingo M
Arch Med Res 2023 Dec;54(8):102924. Epub 2023 Dec 1 doi: 10.1016/j.arcmed.2023.102924. PMID: 38042683
Natural history study of patients with familial platelet disorder with associated myeloid malignancy.
Cunningham L, Merguerian M, Calvo KR, Davis J, Deuitch NT, Dulau-Florea A, Patel N, Yu K, Sacco K, Bhattacharya S, Passi M, Ozkaya N, De Leon S, Chong S, Craft K, Diemer J, Bresciani E, O'Brien K, Andrews EJ, Park N, Hathaway L, Cowen EW, Heller T, Ryan K, Barochia A, Nghiem K, Niemela J, Rosenzweig S, Young DJ, Frischmeyer-Guerrerio PA, Braylan R, Liu PP
Blood 2023 Dec 21;142(25):2146-2158. doi: 10.1182/blood.2023019746. PMID: 37738626Free PMC Article
PCSK9 (Proprotein Convertase Subtilisin/Kexin 9) Enhances Platelet Activation, Thrombosis, and Myocardial Infarct Expansion by Binding to Platelet CD36.
Qi Z, Hu L, Zhang J, Yang W, Liu X, Jia D, Yao Z, Chang L, Pan G, Zhong H, Luo X, Yao K, Sun A, Qian J, Ding Z, Ge J
Circulation 2021 Jan 5;143(1):45-61. Epub 2020 Sep 29 doi: 10.1161/CIRCULATIONAHA.120.046290. PMID: 32988222
Novel functions of platelets in the liver.
Kurokawa T, Zheng YW, Ohkohchi N
J Gastroenterol Hepatol 2016 Apr;31(4):745-51. doi: 10.1111/jgh.13244. PMID: 26632220

Prognosis

Predictors of Response to Treatment with First-Generation Somatostatin Receptor Ligands in Patients with Acromegaly.
Marques-Pamies M, Gil J, Jordà M, Puig-Domingo M
Arch Med Res 2023 Dec;54(8):102924. Epub 2023 Dec 1 doi: 10.1016/j.arcmed.2023.102924. PMID: 38042683
Natural history study of patients with familial platelet disorder with associated myeloid malignancy.
Cunningham L, Merguerian M, Calvo KR, Davis J, Deuitch NT, Dulau-Florea A, Patel N, Yu K, Sacco K, Bhattacharya S, Passi M, Ozkaya N, De Leon S, Chong S, Craft K, Diemer J, Bresciani E, O'Brien K, Andrews EJ, Park N, Hathaway L, Cowen EW, Heller T, Ryan K, Barochia A, Nghiem K, Niemela J, Rosenzweig S, Young DJ, Frischmeyer-Guerrerio PA, Braylan R, Liu PP
Blood 2023 Dec 21;142(25):2146-2158. doi: 10.1182/blood.2023019746. PMID: 37738626Free PMC Article
Clinical and Translational Significance of Basophils in Patients with Cancer.
Chauhan J, Stavraka C, Grandits M, Palhares LCGF, Josephs DH, Lacy KE, Spicer J, Bax HJ, Karagiannis SN
Cells 2022 Jan 27;11(3) doi: 10.3390/cells11030438. PMID: 35159247Free PMC Article
Oro-dental pathologies in acromegaly.
Kreitschmann-Andermahr I, Kohlmann J, Kleist B, Hirschfelder U, Buslei R, Buchfelder M, Siegel S
Endocrine 2018 May;60(2):323-328. Epub 2018 Mar 8 doi: 10.1007/s12020-018-1571-y. PMID: 29520625
Chromogranin A and the tumor microenvironment.
Corti A
Cell Mol Neurobiol 2010 Nov;30(8):1163-70. Epub 2010 Nov 16 doi: 10.1007/s10571-010-9587-8. PMID: 21080056

Clinical prediction guides

Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers-Brief Report.
Witkowski M, Wilcox J, Province V, Wang Z, Nemet I, Tang WHW, Hazen SL
Arterioscler Thromb Vasc Biol 2024 Sep;44(9):2136-2141. Epub 2024 Aug 8 doi: 10.1161/ATVBAHA.124.321019. PMID: 39114916Free PMC Article
Natural history study of patients with familial platelet disorder with associated myeloid malignancy.
Cunningham L, Merguerian M, Calvo KR, Davis J, Deuitch NT, Dulau-Florea A, Patel N, Yu K, Sacco K, Bhattacharya S, Passi M, Ozkaya N, De Leon S, Chong S, Craft K, Diemer J, Bresciani E, O'Brien K, Andrews EJ, Park N, Hathaway L, Cowen EW, Heller T, Ryan K, Barochia A, Nghiem K, Niemela J, Rosenzweig S, Young DJ, Frischmeyer-Guerrerio PA, Braylan R, Liu PP
Blood 2023 Dec 21;142(25):2146-2158. doi: 10.1182/blood.2023019746. PMID: 37738626Free PMC Article
Clinical and Translational Significance of Basophils in Patients with Cancer.
Chauhan J, Stavraka C, Grandits M, Palhares LCGF, Josephs DH, Lacy KE, Spicer J, Bax HJ, Karagiannis SN
Cells 2022 Jan 27;11(3) doi: 10.3390/cells11030438. PMID: 35159247Free PMC Article
ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.
Jain S, Wheeler JR, Walters RW, Agrawal A, Barsic A, Parker R
Cell 2016 Jan 28;164(3):487-98. Epub 2016 Jan 14 doi: 10.1016/j.cell.2015.12.038. PMID: 26777405Free PMC Article
Lysosome-related organelles.
Dell'Angelica EC, Mullins C, Caplan S, Bonifacino JS
FASEB J 2000 Jul;14(10):1265-78. doi: 10.1096/fj.14.10.1265. PMID: 10877819

Recent systematic reviews

Predictors of Response to Treatment with First-Generation Somatostatin Receptor Ligands in Patients with Acromegaly.
Marques-Pamies M, Gil J, Jordà M, Puig-Domingo M
Arch Med Res 2023 Dec;54(8):102924. Epub 2023 Dec 1 doi: 10.1016/j.arcmed.2023.102924. PMID: 38042683
Metabolomics in acromegaly: a systematic review.
Pînzariu O, Georgescu CE
J Investig Med 2023 Aug;71(6):634-645. Epub 2023 May 4 doi: 10.1177/10815589231169452. PMID: 37139720
A systematic review on the role of GRA proteins of Toxoplasma gondii in host immunization.
Rezaei F, Sharif M, Sarvi S, Hejazi SH, Aghayan S, Pagheh AS, Dodangeh S, Daryani A
J Microbiol Methods 2019 Oct;165:105696. Epub 2019 Aug 20 doi: 10.1016/j.mimet.2019.105696. PMID: 31442457
Peripheral iridotomy for pigmentary glaucoma.
Michelessi M, Lindsley K
Cochrane Database Syst Rev 2016 Feb 12;2(2):CD005655. doi: 10.1002/14651858.CD005655.pub2. PMID: 26871761Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...