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Abnormal pituitary gland morphology

MedGen UID:
1843446
•Concept ID:
C5779790
•
Anatomical Abnormality
Synonym: Abnormality of the pituitary gland
 
HPO: HP:0012503

Definition

An anomaly of the pituitary gland. [from HPO]

Professional guidelines

PubMed

Diagnosis and management of congenital hypopituitarism in children.
Castets S, Thomas-Teinturier C, Villanueva C, Amsellem J, Barat P, Brun G, Quoc EB, Carel JC, De Filippo GP, Kipnis C, Martinerie L, Vergier J, Saveanu A, Teissier N, Coutant R, Léger J, Reynaud R
Arch Pediatr 2024 Apr;31(3):165-171. Epub 2024 Mar 27 doi: 10.1016/j.arcped.2024.01.003. PMID: 38538470
Pituitary stalk interruption syndrome: cause, clinical manifestations, diagnosis, and management.
Voutetakis A, Sertedaki A, Dacou-Voutetakis C
Curr Opin Pediatr 2016 Aug;28(4):545-50. doi: 10.1097/MOP.0000000000000378. PMID: 27386973
Primary amenorrhea: diagnosis and management.
Marsh CA, Grimstad FW
Obstet Gynecol Surv 2014 Oct;69(10):603-12. doi: 10.1097/OGX.0000000000000111. PMID: 25336070

Recent clinical studies

Etiology

Phakomatoses and Endocrine Gland Tumors: Noteworthy and (Not so) Rare Associations.
Chevalier B, Dupuis H, Jannin A, Lemaitre M, Do Cao C, Cardot-Bauters C, Espiard S, Vantyghem MC
Front Endocrinol (Lausanne) 2021;12:678869. Epub 2021 May 6 doi: 10.3389/fendo.2021.678869. PMID: 34025587Free PMC Article
Interconnection between circadian clocks and thyroid function.
Ikegami K, Refetoff S, Van Cauter E, Yoshimura T
Nat Rev Endocrinol 2019 Oct;15(10):590-600. Epub 2019 Aug 12 doi: 10.1038/s41574-019-0237-z. PMID: 31406343Free PMC Article
The Hypothalamic-Pituitary Axis and Autoantibody Related Disorders.
Cocco C, Brancia C, Corda G, Ferri GL
Int J Mol Sci 2017 Nov 3;18(11) doi: 10.3390/ijms18112322. PMID: 29099758Free PMC Article
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592

Diagnosis

Neuroimaging of the Pituitary Gland: Practical Anatomy and Pathology.
Chapman PR, Singhal A, Gaddamanugu S, Prattipati V
Radiol Clin North Am 2020 Nov;58(6):1115-1133. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.009. PMID: 33040852
Sellar Tumors.
Schwetye KE, Dahiya SM
Surg Pathol Clin 2020 Jun;13(2):305-329. doi: 10.1016/j.path.2020.02.006. PMID: 32389269
Diabetes insipidus.
Christ-Crain M, Bichet DG, Fenske WK, Goldman MB, Rittig S, Verbalis JG, Verkman AS
Nat Rev Dis Primers 2019 Aug 8;5(1):54. doi: 10.1038/s41572-019-0103-2. PMID: 31395885
Rathke's cleft cyst.
Larkin S, Karavitaki N, Ansorge O
Handb Clin Neurol 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4. PMID: 25248592
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Therapy

Endocrine and Metabolic Manifestations of Snakebite Envenoming.
Bhattacharya S, Krishnamurthy A, Gopalakrishnan M, Kalra S, Kantroo V, Aggarwal S, Surana V
Am J Trop Med Hyg 2020 Oct;103(4):1388-1396. doi: 10.4269/ajtmh.20-0161. PMID: 32602439Free PMC Article
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Spontaneous intracranial hypotension.
Mokri B
Curr Neurol Neurosci Rep 2001 Mar;1(2):109-17. doi: 10.1007/s11910-001-0005-y. PMID: 11898506
Spontaneous intracranial hypotension.
Mokri B
Curr Pain Headache Rep 2001 Jun;5(3):284-91. doi: 10.1007/s11916-001-0045-7. PMID: 11309218
Adolescent menstrual irregularity.
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175

Prognosis

Architects of Pituitary Tumour Growth.
Sabatino ME, Grondona E, De Paul AL
Front Endocrinol (Lausanne) 2022;13:924942. Epub 2022 Jun 28 doi: 10.3389/fendo.2022.924942. PMID: 35837315Free PMC Article
Phakomatoses and Endocrine Gland Tumors: Noteworthy and (Not so) Rare Associations.
Chevalier B, Dupuis H, Jannin A, Lemaitre M, Do Cao C, Cardot-Bauters C, Espiard S, Vantyghem MC
Front Endocrinol (Lausanne) 2021;12:678869. Epub 2021 May 6 doi: 10.3389/fendo.2021.678869. PMID: 34025587Free PMC Article
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Rathke's cleft cysts.
Kanter AS, Sansur CA, Jane JAJ Jr, Laws ERJ Jr
Front Horm Res 2006;34:127-157. doi: 10.1159/000091579. PMID: 16474219
Neuro-osteology.
Kjaer I
Crit Rev Oral Biol Med 1998;9(2):224-44. doi: 10.1177/10454411980090020501. PMID: 9603237

Clinical prediction guides

The impact of transsphenoidal surgery on pituitary function in patients with non-functioning macroadenomas.
Mavromati M, Mavrakanas T, Jornayvaz FR, Schaller K, Fitsiori A, Vargas MI, Lobrinus JA, Merkler D, Egervari K, Philippe J, Leboulleux S, Momjian S
Endocrine 2023 Aug;81(2):340-348. Epub 2023 May 24 doi: 10.1007/s12020-023-03400-z. PMID: 37222882Free PMC Article
Architects of Pituitary Tumour Growth.
Sabatino ME, Grondona E, De Paul AL
Front Endocrinol (Lausanne) 2022;13:924942. Epub 2022 Jun 28 doi: 10.3389/fendo.2022.924942. PMID: 35837315Free PMC Article
Complications of acromegaly: thyroid and colon.
Tirosh A, Shimon I
Pituitary 2017 Feb;20(1):70-75. doi: 10.1007/s11102-016-0744-z. PMID: 27631334
Rathke's cleft cysts.
Kanter AS, Sansur CA, Jane JAJ Jr, Laws ERJ Jr
Front Horm Res 2006;34:127-157. doi: 10.1159/000091579. PMID: 16474219
PIT1 abnormality.
Tatsumi K, Amino N
Growth Horm IGF Res 1999 Jun;9 Suppl B:18-22; discussion 23. doi: 10.1016/s1096-6374(99)80076-8. PMID: 10549301

Recent systematic reviews

Primary Tumors of the Posterior Pituitary Gland: A Systematic Review of the Literature in Light of the New 2017 World Health Organization Classification of Pituitary Tumors.
Whipple SG, Savardekar AR, Rao S, Mahadevan A, Guthikonda B, Kosty JA
World Neurosurg 2021 Jan;145:148-158. Epub 2020 Sep 8 doi: 10.1016/j.wneu.2020.09.023. PMID: 32916355
Pituitary dysfunction in granulomatosis with polyangiitis.
Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O
Pituitary 2017 Oct;20(5):594-601. doi: 10.1007/s11102-017-0811-0. PMID: 28540625Free PMC Article
Case Report of a Primary Pituitary Abscess and Systematic Literature Review of Pituitary Abscess with a Focus on Patient Outcomes.
Agyei JO, Lipinski LJ, Leonardo J
World Neurosurg 2017 May;101:76-92. Epub 2017 Jan 31 doi: 10.1016/j.wneu.2017.01.077. PMID: 28153622
A systematic review of the activity of the hypothalamic-pituitary-adrenal axis in first episode psychosis.
Borges S, Gayer-Anderson C, Mondelli V
Psychoneuroendocrinology 2013 May;38(5):603-11. Epub 2013 Jan 28 doi: 10.1016/j.psyneuen.2012.12.025. PMID: 23369532
Cerebral aneurysms with intrasellar extension: a systematic review of clinical, anatomical, and treatment characteristics.
Hanak BW, Zada G, Nayar VV, Thiex R, Du R, Day AL, Laws ER
J Neurosurg 2012 Jan;116(1):164-78. Epub 2011 Nov 4 doi: 10.3171/2011.9.JNS11380. PMID: 22054212

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