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Bacterial infection of central nervous system

MedGen UID:
199829
Concept ID:
C0752180
Disease or Syndrome
Synonyms: Bacterial Infections, Central Nervous System; Central Nervous System Bacterial Infections; Infections, Bacterial, Central Nervous System
SNOMED CT: Bacterial infection of central nervous system (128119004)

Definition

Bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces. [from MeSH]

Professional guidelines

PubMed

Arkell P, Wilson R, Watkins K, Antcliffe DB, Gilchrist M, Wilson M, Rawson TM, Holmes A
J Antimicrob Chemother 2022 Nov 28;77(12):3408-3413. doi: 10.1093/jac/dkac332. PMID: 36227686Free PMC Article

Recent clinical studies

Etiology

Skar G, Flannigan L, Latch R, Snowden J
Pediatr Rev 2024 Jun 1;45(6):305-315. doi: 10.1542/pir.2023-006013. PMID: 38821894
Tavares T, Pinho L, Bonifácio Andrade E
Clin Microbiol Rev 2022 Apr 20;35(2):e0007921. Epub 2022 Feb 16 doi: 10.1128/cmr.00079-21. PMID: 35170986Free PMC Article
Suthar R, Sankhyan N
Indian J Pediatr 2019 Jan;86(1):60-69. Epub 2018 Jan 3 doi: 10.1007/s12098-017-2477-z. PMID: 29297142
Monticelli J, Knezevich A, Luzzati R, Di Bella S
J Infect Chemother 2018 Apr;24(4):237-246. Epub 2018 Feb 1 doi: 10.1016/j.jiac.2018.01.001. PMID: 29396199
van de Beek D, Cabellos C, Dzupova O, Esposito S, Klein M, Kloek AT, Leib SL, Mourvillier B, Ostergaard C, Pagliano P, Pfister HW, Read RC, Sipahi OR, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB)
Clin Microbiol Infect 2016 May;22 Suppl 3:S37-62. Epub 2016 Apr 7 doi: 10.1016/j.cmi.2016.01.007. PMID: 27062097

Diagnosis

Tavares T, Pinho L, Bonifácio Andrade E
Clin Microbiol Rev 2022 Apr 20;35(2):e0007921. Epub 2022 Feb 16 doi: 10.1128/cmr.00079-21. PMID: 35170986Free PMC Article
Shahan B, Choi EY, Nieves G
Am Fam Physician 2021 Apr 1;103(7):422-428. PMID: 33788511
Wall EC, Chan JM, Gil E, Heyderman RS
Curr Opin Neurol 2021 Jun 1;34(3):386-395. doi: 10.1097/WCO.0000000000000934. PMID: 33767093Free PMC Article
Suthar R, Sankhyan N
Indian J Pediatr 2019 Jan;86(1):60-69. Epub 2018 Jan 3 doi: 10.1007/s12098-017-2477-z. PMID: 29297142
Giovane RA, Lavender PD
Prim Care 2018 Sep;45(3):505-518. Epub 2018 Jul 9 doi: 10.1016/j.pop.2018.05.007. PMID: 30115337

Therapy

Tavares T, Pinho L, Bonifácio Andrade E
Clin Microbiol Rev 2022 Apr 20;35(2):e0007921. Epub 2022 Feb 16 doi: 10.1128/cmr.00079-21. PMID: 35170986Free PMC Article
Wall EC, Chan JM, Gil E, Heyderman RS
Curr Opin Neurol 2021 Jun 1;34(3):386-395. doi: 10.1097/WCO.0000000000000934. PMID: 33767093Free PMC Article
Nau R, Blei C, Eiffert H
Clin Microbiol Rev 2020 Jun 17;33(3) Epub 2020 Apr 29 doi: 10.1128/CMR.00190-19. PMID: 32349999Free PMC Article
Suthar R, Sankhyan N
Indian J Pediatr 2019 Jan;86(1):60-69. Epub 2018 Jan 3 doi: 10.1007/s12098-017-2477-z. PMID: 29297142
Giovane RA, Lavender PD
Prim Care 2018 Sep;45(3):505-518. Epub 2018 Jul 9 doi: 10.1016/j.pop.2018.05.007. PMID: 30115337

Prognosis

Shahan B, Choi EY, Nieves G
Am Fam Physician 2021 Apr 1;103(7):422-428. PMID: 33788511
Schaller MA, Wicke F, Foerch C, Weidauer S
Clin Neuroradiol 2019 Mar;29(1):3-18. Epub 2018 Sep 17 doi: 10.1007/s00062-018-0726-9. PMID: 30225516
Giovane RA, Lavender PD
Prim Care 2018 Sep;45(3):505-518. Epub 2018 Jul 9 doi: 10.1016/j.pop.2018.05.007. PMID: 30115337
Tuddenham S, Ghanem KG
Sex Transm Dis 2018 Mar;45(3):147-151. doi: 10.1097/OLQ.0000000000000723. PMID: 29420441Free PMC Article
Tsiodras S, Kelesidis I, Kelesidis T, Stamboulis E, Giamarellou H
J Infect 2005 Dec;51(5):343-54. Epub 2005 Sep 19 doi: 10.1016/j.jinf.2005.07.005. PMID: 16181677

Clinical prediction guides

Hasbun R
JAMA 2022 Dec 6;328(21):2147-2154. doi: 10.1001/jama.2022.20521. PMID: 36472590
Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD Jr, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN)
JAMA Pediatr 2019 Apr 1;173(4):342-351. doi: 10.1001/jamapediatrics.2018.5501. PMID: 30776077Free PMC Article
Pruitt AA
Neurol Clin 2014 Nov;32(4):1117-31. Epub 2014 Oct 24 doi: 10.1016/j.ncl.2014.07.009. PMID: 25439297
Radetsky M
Pediatr Infect Dis J 2014 Feb;33(2):204-7. doi: 10.1097/01.inf.0000435508.67490.f0. PMID: 24413408
Roos KL, van de Beek D
Handb Clin Neurol 2010;96:51-63. Epub 2010 Jan 19 doi: 10.1016/S0072-9752(09)96004-3. PMID: 20109674

Recent systematic reviews

Navarro-Flores A, Fernandez-Chinguel JE, Pacheco-Barrios N, Soriano-Moreno DR, Pacheco-Barrios K
J Neurol 2022 Jul;269(7):3482-3494. Epub 2022 Mar 15 doi: 10.1007/s00415-022-11052-8. PMID: 35288778Free PMC Article
Margalit I, Lebeaux D, Tishler O, Goldberg E, Bishara J, Yahav D, Coussement J
Clin Microbiol Infect 2021 Apr;27(4):550-558. Epub 2021 Jan 5 doi: 10.1016/j.cmi.2020.12.019. PMID: 33418019
Oordt-Speets AM, Bolijn R, van Hoorn RC, Bhavsar A, Kyaw MH
PLoS One 2018;13(6):e0198772. Epub 2018 Jun 11 doi: 10.1371/journal.pone.0198772. PMID: 29889859Free PMC Article
Brouwer MC, McIntyre P, Prasad K, van de Beek D
Cochrane Database Syst Rev 2015 Sep 12;2015(9):CD004405. doi: 10.1002/14651858.CD004405.pub5. PMID: 26362566Free PMC Article
Brouwer MC, Coutinho JM, van de Beek D
Neurology 2014 Mar 4;82(9):806-13. Epub 2014 Jan 29 doi: 10.1212/WNL.0000000000000172. PMID: 24477107

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