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Infection

MedGen UID:: 811352
•Concept ID:: C3714514
•: Pathologic Function

Synonyms:

Infection and Infestation; Infections; Infections and Infestations; Infestation and Infection; Infestations and Infections

Definition

The invasion of an organism''s body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVInfection

Pathological Conditions, Signs and Symptoms
- Clinical finding
  - Finding by Cause
    - Infection

Professional guidelines

PubMed

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.

Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ Jr, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL
Eur Respir J 2020 Jul;56(1) Epub 2020 Jul 7 doi: 10.1183/13993003.00535-2020. PMID: 32636299 Free PMC Article

Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of America.

Nicolle LE, Gupta K, Bradley SF, Colgan R, DeMuri GP, Drekonja D, Eckert LO, Geerlings SE, Köves B, Hooton TM, Juthani-Mehta M, Knight SL, Saint S, Schaeffer AJ, Trautner B, Wullt B, Siemieniuk R
Clin Infect Dis 2019 May 2;68(10):e83-e110. doi: 10.1093/cid/ciy1121. PMID: 30895288

Hepatitis B: Screening, Prevention, Diagnosis, and Treatment.

Wilkins T, Sams R, Carpenter M
Am Fam Physician 2019 Mar 1;99(5):314-323. PMID: 30811163

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Recent clinical studies

Etiology

The EBJIS definition of periprosthetic joint infection.

McNally M, Sousa R, Wouthuyzen-Bakker M, Chen AF, Soriano A, Vogely HC, Clauss M, Higuera CA, Trebše R
Bone Joint J 2021 Jan;103-B(1):18-25. doi: 10.1302/0301-620X.103B1.BJJ-2020-1381.R1. PMID: 33380199 Free PMC Article

Burn Wound Colonization, Infection, and Sepsis.

Ladhani HA, Yowler CJ, Claridge JA
Surg Infect (Larchmt) 2021 Feb;22(1):44-48. Epub 2020 Oct 20 doi: 10.1089/sur.2020.346. PMID: 33085576

Urinary tract infection in pediatrics: an overview.

Simões E Silva AC, Oliveira EA, Mak RH
J Pediatr (Rio J) 2020 Mar-Apr;96 Suppl 1(Suppl 1):65-79. Epub 2019 Nov 26 doi: 10.1016/j.jped.2019.10.006. PMID: 31783012 Free PMC Article

Progressive Multifocal Leukoencephalopathy.

Grebenciucova E, Berger JR
Neurol Clin 2018 Nov;36(4):739-750. doi: 10.1016/j.ncl.2018.06.002. PMID: 30366552

Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy.

Williamson PR, Jarvis JN, Panackal AA, Fisher MC, Molloy SF, Loyse A, Harrison TS
Nat Rev Neurol 2017 Jan;13(1):13-24. Epub 2016 Nov 25 doi: 10.1038/nrneurol.2016.167. PMID: 27886201

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Diagnosis

Dengue infection: Global importance, immunopathology and management.

Kularatne SA, Dalugama C
Clin Med (Lond) 2022 Jan;22(1):9-13. doi: 10.7861/clinmed.2021-0791. PMID: 35078789 Free PMC Article

Exosomes in HIV infection.

Chen J, Li C, Li R, Chen H, Chen D, Li W
Curr Opin HIV AIDS 2021 Sep 1;16(5):262-270. doi: 10.1097/COH.0000000000000694. PMID: 34321416 Free PMC Article

The EBJIS definition of periprosthetic joint infection.

Urinary tract infection in pediatrics: an overview.

Simões E Silva AC, Oliveira EA, Mak RH
J Pediatr (Rio J) 2020 Mar-Apr;96 Suppl 1(Suppl 1):65-79. Epub 2019 Nov 26 doi: 10.1016/j.jped.2019.10.006. PMID: 31783012 Free PMC Article

American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update.

Ban KA, Minei JP, Laronga C, Harbrecht BG, Jensen EH, Fry DE, Itani KM, Dellinger EP, Ko CY, Duane TM
J Am Coll Surg 2017 Jan;224(1):59-74. Epub 2016 Nov 30 doi: 10.1016/j.jamcollsurg.2016.10.029. PMID: 27915053

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Therapy

Closing the evidence gap in infectious disease: point-of-care randomization and informed consent.

Huttner A, Leibovici L, Theuretzbacher U, Huttner B, Paul M
Clin Microbiol Infect 2017 Feb;23(2):73-77. Epub 2016 Aug 3 doi: 10.1016/j.cmi.2016.07.029. PMID: 27497812

Subclavian hemodialysis catheter infections.

Dahlberg PJ, Yutuc WR, Newcomer KL
Am J Kidney Dis 1986 May;7(5):421-7. doi: 10.1016/s0272-6386(86)80092-0. PMID: 3518423

Single-dose antibiotic treatment for uncomplicated urinary tract infections. Less for less?

Philbrick JT, Bracikowski JP
Arch Intern Med 1985 Sep;145(9):1672-8. PMID: 3896186

Topical acyclovir in the treatment of genital herpes: a comparison with systemic therapy.

Fiddian AP, Kinghorn GR, Goldmeier D, Rees E, Rodin P, Thin RN, de Konig GA
J Antimicrob Chemother 1983 Sep;12 Suppl B:67-77. doi: 10.1093/jac/12.suppl_b.67. PMID: 6355053

Is your enema really necessary?

Romney ML, Gordon H
Br Med J (Clin Res Ed) 1981 Apr 18;282(6272):1269-71. doi: 10.1136/bmj.282.6272.1269. PMID: 6784809 Free PMC Article

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Prognosis

Challenges and Updates in the Diagnosis and Treatment of Infective Endocarditis.

Sebastian SA, Co EL, Mehendale M, Sudan S, Manchanda K, Khan S
Curr Probl Cardiol 2022 Sep;47(9):101267. Epub 2022 May 28 doi: 10.1016/j.cpcardiol.2022.101267. PMID: 35636519

Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis.

Markwart R, Saito H, Harder T, Tomczyk S, Cassini A, Fleischmann-Struzek C, Reichert F, Eckmanns T, Allegranzi B
Intensive Care Med 2020 Aug;46(8):1536-1551. Epub 2020 Jun 26 doi: 10.1007/s00134-020-06106-2. PMID: 32591853 Free PMC Article

Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis.

Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F
Lancet Glob Health 2020 Feb;8(2):e191-e203. Epub 2019 Dec 4 doi: 10.1016/S2214-109X(19)30482-6. PMID: 31812369 Free PMC Article

Global Cancer Incidence and Mortality Rates and Trends--An Update.

Torre LA, Siegel RL, Ward EM, Jemal A
Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):16-27. Epub 2015 Dec 14 doi: 10.1158/1055-9965.EPI-15-0578. PMID: 26667886

Epidemiology of stomach cancer.

Brenner H, Rothenbacher D, Arndt V
Methods Mol Biol 2009;472:467-77. doi: 10.1007/978-1-60327-492-0_23. PMID: 19107449

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Clinical prediction guides

A Clinical Prediction Tool for MRI in Emergency Department Patients with Spinal Infection.

Shroyer SR, Davis WT, April MD, Long B, Boys G, Mehta SG, Mercaldo SF
West J Emerg Med 2021 Aug 30;22(5):1156-1166. doi: 10.5811/westjem.2021.5.52007. PMID: 34546893 Free PMC Article

Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.

Alexander Y, Osto E, Schmidt-Trucksäss A, Shechter M, Trifunovic D, Duncker DJ, Aboyans V, Bäck M, Badimon L, Cosentino F, De Carlo M, Dorobantu M, Harrison DG, Guzik TJ, Hoefer I, Morris PD, Norata GD, Suades R, Taddei S, Vilahur G, Waltenberger J, Weber C, Wilkinson F, Bochaton-Piallat ML, Evans PC
Cardiovasc Res 2021 Jan 1;117(1):29-42. doi: 10.1093/cvr/cvaa085. PMID: 32282914 Free PMC Article

Diagnostic accuracy and predictive value in differentiating the severity of dengue infection.

Low GKK, Kagize J, Faull KJ, Azahar A
Trop Med Int Health 2019 Oct;24(10):1169-1197. Epub 2019 Aug 19 doi: 10.1111/tmi.13294. PMID: 31373098

Which preoperative respiratory evaluation?

Zraier S, Haouache H, Dhonneur G
Ann Fr Anesth Reanim 2014 Jul-Aug;33(7-8):453-6. Epub 2014 Aug 29 doi: 10.1016/j.annfar.2014.07.743. PMID: 25168302

Virtual laryngoscopy--preliminary experience.

Byrne AT, Walshe P, McShane D, Hamilton S
Eur J Radiol 2005 Oct;56(1):38-42. doi: 10.1016/j.ejrad.2005.02.006. PMID: 16168262

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Recent systematic reviews

Incidence of Urinary Tract Infection Among Patients: Systematic Review and Meta-Analysis.

Mengistu DA, Alemu A, Abdukadir AA, Mohammed Husen A, Ahmed F, Mohammed B
Inquiry 2023 Jan-Dec;60:469580231168746. doi: 10.1177/00469580231168746. PMID: 37096884 Free PMC Article

Global Incidence of Surgical Site Infection Among Patients: Systematic Review and Meta-Analysis.

Mengistu DA, Alemu A, Abdukadir AA, Mohammed Husen A, Ahmed F, Mohammed B, Musa I
Inquiry 2023 Jan-Dec;60:469580231162549. doi: 10.1177/00469580231162549. PMID: 36964747 Free PMC Article

Effectiveness and safety of prenatal valacyclovir for congenital cytomegalovirus infection: systematic review and meta-analysis.

D'Antonio F, Marinceu D, Prasad S, Khalil A
Ultrasound Obstet Gynecol 2023 Apr;61(4):436-444. doi: 10.1002/uog.26136. PMID: 36484439

Impact of environmental hygiene interventions on healthcare-associated infections and patient colonization: a systematic review.

Peters A, Schmid MN, Parneix P, Lebowitz D, de Kraker M, Sauser J, Zingg W, Pittet D
Antimicrob Resist Infect Control 2022 Feb 19;11(1):38. doi: 10.1186/s13756-022-01075-1. PMID: 35183259 Free PMC Article

Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis.

Allegranzi B, Bagheri Nejad S, Combescure C, Graafmans W, Attar H, Donaldson L, Pittet D
Lancet 2011 Jan 15;377(9761):228-41. Epub 2010 Dec 9 doi: 10.1016/S0140-6736(10)61458-4. PMID: 21146207

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