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Neoplastic Post-Transplant Lymphoproliferative Disorder

MedGen UID:
235365
•Concept ID:
C1334942
•
Neoplastic Process
Synonyms: Neoplastic PTLD; Post-Transplant Lymphocytic Neoplasm; Post-Transplant Lymphoproliferative Neoplasm; Post-Transplant Neoplastic Lymphoproliferative Disorder

Definition

A lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterized by the presence of tissue destruction and effacement of the architecture of the involved tissues. It includes the following variants: polymorphic, monomorphic, and classical Hodgkin lymphoma post-transplant lymphoproliferative disorders. [from NCI]

Professional guidelines

PubMed

Long-term side effects of treatment with mTOR inhibitors in children after renal transplantation.
Kranz B, Wingen AM, Vester U, König J, Hoyer PF
Pediatr Nephrol 2013 Aug;28(8):1293-8. Epub 2013 Apr 13 doi: 10.1007/s00467-013-2459-y. PMID: 23584849
Role of fine-needle aspiration in clinical management of transplant patients.
Siddiqui MT, Reddy VB, Castelli MJ, Gattuso P
Diagn Cytopathol 1997 Dec;17(6):429-35. doi: 10.1002/(sici)1097-0339(199712)17:6<429::aid-dc10>3.0.co;2-o. PMID: 9407203

Recent clinical studies

Diagnosis

Diagnosis and treatment of neoplastic post-transplant lymphoproliferative disorder following hematopoietic stem cell transplant in β-thalassemia: A pediatric case report.
Zhang X, Hao W, Xu T, Liu S, Jiang H
Medicine (Baltimore) 2017 Dec;96(52):e9055. doi: 10.1097/MD.0000000000009055. PMID: 29384898Free PMC Article

Therapy

Diagnosis and treatment of neoplastic post-transplant lymphoproliferative disorder following hematopoietic stem cell transplant in β-thalassemia: A pediatric case report.
Zhang X, Hao W, Xu T, Liu S, Jiang H
Medicine (Baltimore) 2017 Dec;96(52):e9055. doi: 10.1097/MD.0000000000009055. PMID: 29384898Free PMC Article

Prognosis

Diagnosis and treatment of neoplastic post-transplant lymphoproliferative disorder following hematopoietic stem cell transplant in β-thalassemia: A pediatric case report.
Zhang X, Hao W, Xu T, Liu S, Jiang H
Medicine (Baltimore) 2017 Dec;96(52):e9055. doi: 10.1097/MD.0000000000009055. PMID: 29384898Free PMC Article

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