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Grade 2 Cataract, CTCAE

MedGen UID:
281560
Concept ID:
C1557308
Finding

Definition

Symptomatic; moderate decrease in visual acuity (best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline); glare symptoms affecting instrumental ADL [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 2 Cataract, CTCAE

Professional guidelines

PubMed

Meric-Bernstam F, Hollebecque A, Furuse J, Oh DY, Bridgewater JA, Shimura M, Anderson B, Hangai N, Wacheck V, Goyal L
Clin Cancer Res 2024 Apr 15;30(8):1466-1477. doi: 10.1158/1078-0432.CCR-23-2646. PMID: 38329716Free PMC Article

Recent clinical studies

Etiology

Shelukar S, Fernandez C, Bas Z, Komarnicky L, Lally SE, Shields CL, Binder A, Porcu P, Alpdogan O, Martinez-Outschoorn U, Shi W
Chin Clin Oncol 2022 Dec;11(6):44. doi: 10.21037/cco-22-84. PMID: 36632978
Hoffmann C, Rating P, Bechrakis N, Eckstein A, Sokolenko E, Jabbarli L, Westekemper H, Mohr C, Schmeling C, Huettmann A, von Tresckow J, Göricke S, Deuschl C, Johansson P, Poettgen C, Gauler T, Guberina N, Moliavi S, Stuschke M, Guberina M
Hematol Oncol 2022 Dec;40(5):922-929. Epub 2022 Aug 7 doi: 10.1002/hon.3053. PMID: 35857866
Zenda S, Kawashima M, Arahira S, Kohno R, Nishio T, Tahara M, Hayashi R, Akimoto T
Int J Clin Oncol 2015 Jun;20(3):447-54. Epub 2014 Aug 20 doi: 10.1007/s10147-014-0737-8. PMID: 25135461
Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jäkel O, Karger CP, Edler L, Debus J
Int J Radiat Oncol Biol Phys 2007 Jan 1;67(1):171-7. Epub 2006 Oct 23 doi: 10.1016/j.ijrobp.2006.08.027. PMID: 17056193

Diagnosis

Shelukar S, Fernandez C, Bas Z, Komarnicky L, Lally SE, Shields CL, Binder A, Porcu P, Alpdogan O, Martinez-Outschoorn U, Shi W
Chin Clin Oncol 2022 Dec;11(6):44. doi: 10.21037/cco-22-84. PMID: 36632978
Hoffmann C, Rating P, Bechrakis N, Eckstein A, Sokolenko E, Jabbarli L, Westekemper H, Mohr C, Schmeling C, Huettmann A, von Tresckow J, Göricke S, Deuschl C, Johansson P, Poettgen C, Gauler T, Guberina N, Moliavi S, Stuschke M, Guberina M
Hematol Oncol 2022 Dec;40(5):922-929. Epub 2022 Aug 7 doi: 10.1002/hon.3053. PMID: 35857866

Therapy

Shelukar S, Fernandez C, Bas Z, Komarnicky L, Lally SE, Shields CL, Binder A, Porcu P, Alpdogan O, Martinez-Outschoorn U, Shi W
Chin Clin Oncol 2022 Dec;11(6):44. doi: 10.21037/cco-22-84. PMID: 36632978
Lockney NA, Friedman DN, Wexler LH, Sklar CA, Casey DL, Wolden SL
Pediatr Blood Cancer 2016 Sep;63(9):1608-14. Epub 2016 May 16 doi: 10.1002/pbc.26061. PMID: 27195454Free PMC Article
Zenda S, Kawashima M, Arahira S, Kohno R, Nishio T, Tahara M, Hayashi R, Akimoto T
Int J Clin Oncol 2015 Jun;20(3):447-54. Epub 2014 Aug 20 doi: 10.1007/s10147-014-0737-8. PMID: 25135461
Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jäkel O, Karger CP, Edler L, Debus J
Int J Radiat Oncol Biol Phys 2007 Jan 1;67(1):171-7. Epub 2006 Oct 23 doi: 10.1016/j.ijrobp.2006.08.027. PMID: 17056193

Prognosis

Hoffmann C, Rating P, Bechrakis N, Eckstein A, Sokolenko E, Jabbarli L, Westekemper H, Mohr C, Schmeling C, Huettmann A, von Tresckow J, Göricke S, Deuschl C, Johansson P, Poettgen C, Gauler T, Guberina N, Moliavi S, Stuschke M, Guberina M
Hematol Oncol 2022 Dec;40(5):922-929. Epub 2022 Aug 7 doi: 10.1002/hon.3053. PMID: 35857866
Zenda S, Kawashima M, Arahira S, Kohno R, Nishio T, Tahara M, Hayashi R, Akimoto T
Int J Clin Oncol 2015 Jun;20(3):447-54. Epub 2014 Aug 20 doi: 10.1007/s10147-014-0737-8. PMID: 25135461
Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jäkel O, Karger CP, Edler L, Debus J
Int J Radiat Oncol Biol Phys 2007 Jan 1;67(1):171-7. Epub 2006 Oct 23 doi: 10.1016/j.ijrobp.2006.08.027. PMID: 17056193

Clinical prediction guides

Hoffmann C, Rating P, Bechrakis N, Eckstein A, Sokolenko E, Jabbarli L, Westekemper H, Mohr C, Schmeling C, Huettmann A, von Tresckow J, Göricke S, Deuschl C, Johansson P, Poettgen C, Gauler T, Guberina N, Moliavi S, Stuschke M, Guberina M
Hematol Oncol 2022 Dec;40(5):922-929. Epub 2022 Aug 7 doi: 10.1002/hon.3053. PMID: 35857866
Zenda S, Kawashima M, Arahira S, Kohno R, Nishio T, Tahara M, Hayashi R, Akimoto T
Int J Clin Oncol 2015 Jun;20(3):447-54. Epub 2014 Aug 20 doi: 10.1007/s10147-014-0737-8. PMID: 25135461
Schulz-Ertner D, Nikoghosyan A, Hof H, Didinger B, Combs SE, Jäkel O, Karger CP, Edler L, Debus J
Int J Radiat Oncol Biol Phys 2007 Jan 1;67(1):171-7. Epub 2006 Oct 23 doi: 10.1016/j.ijrobp.2006.08.027. PMID: 17056193

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