U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Adverse Event Associated with Ocular and Visual Systems

MedGen UID:
286045
•Concept ID:
C1557306
•
Finding
Synonym: Adverse Event Associated with Ocular and Visual

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdverse Event Associated with Ocular and Visual Systems

Professional guidelines

PubMed

Ocular Effects of MEK Inhibitor Therapy: Literature Review, Clinical Presentation, and Best Practices for Mitigation.
Jeng-Miller KW, Miller MA, Heier JS
Oncologist 2024 May 3;29(5):e616-e621. doi: 10.1093/oncolo/oyae014. PMID: 38527005Free PMC Article
A Novel Risk Stratification-Based Immunomodulatory Treatment Strategy for Vogt-Koyanagi-Harada Disease.
Jin K, Liang A, Song H, Xiao F, Gao F, Han X, Zhang M, Zhao C
Am J Ophthalmol 2024 Jun;262:25-33. Epub 2024 Feb 16 doi: 10.1016/j.ajo.2024.01.035. PMID: 38369223
LipiFlow for the treatment of dry eye disease.
Pucker AD, Yim TW, Rueff E, Ngo W, Tichenor AA, Conto JE
Cochrane Database Syst Rev 2024 Feb 5;2(2):CD015448. doi: 10.1002/14651858.CD015448.pub2. PMID: 38314898Free PMC Article

Recent clinical studies

Etiology

Risk of ocular adverse events with aromatase inhibitors.
Feng ZX, Sriranganathan A, Lo C, Liu V, Maberley D, Etminan M
Can J Ophthalmol 2024 Oct;59(5):e431-e434. Epub 2023 Nov 3 doi: 10.1016/j.jcjo.2023.10.013. PMID: 37931898
Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Monés J, Singh RP, Ribeiro R, Wykoff CC; OAKS and DERBY study investigators
Lancet 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9. PMID: 37865470
Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials.
Heier JS, Khanani AM, Quezada Ruiz C, Basu K, Ferrone PJ, Brittain C, Figueroa MS, Lin H, Holz FG, Patel V, Lai TYY, Silverman D, Regillo C, Swaminathan B, Viola F, Cheung CMG, Wong TY; TENAYA and LUCERNE Investigators
Lancet 2022 Feb 19;399(10326):729-740. Epub 2022 Jan 24 doi: 10.1016/S0140-6736(22)00010-1. PMID: 35085502
Systemic lupus erythematosus and ocular involvement: an overview.
Dammacco R
Clin Exp Med 2018 May;18(2):135-149. Epub 2017 Dec 14 doi: 10.1007/s10238-017-0479-9. PMID: 29243035
Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial.
Nguyen QD, Merrill PT, Jaffe GJ, Dick AD, Kurup SK, Sheppard J, Schlaen A, Pavesio C, Cimino L, Van Calster J, Camez AA, Kwatra NV, Song AP, Kron M, Tari S, Brézin AP
Lancet 2016 Sep 17;388(10050):1183-92. Epub 2016 Aug 16 doi: 10.1016/S0140-6736(16)31339-3. PMID: 27542302

Diagnosis

Gene Editing for CEP290-Associated Retinal Degeneration.
Pierce EA, Aleman TS, Jayasundera KT, Ashimatey BS, Kim K, Rashid A, Jaskolka MC, Myers RL, Lam BL, Bailey ST, Comander JI, Lauer AK, Maguire AM, Pennesi ME
N Engl J Med 2024 Jun 6;390(21):1972-1984. Epub 2024 May 6 doi: 10.1056/NEJMoa2309915. PMID: 38709228Free PMC Article
Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Monés J, Singh RP, Ribeiro R, Wykoff CC; OAKS and DERBY study investigators
Lancet 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9. PMID: 37865470
Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials.
Heier JS, Khanani AM, Quezada Ruiz C, Basu K, Ferrone PJ, Brittain C, Figueroa MS, Lin H, Holz FG, Patel V, Lai TYY, Silverman D, Regillo C, Swaminathan B, Viola F, Cheung CMG, Wong TY; TENAYA and LUCERNE Investigators
Lancet 2022 Feb 19;399(10326):729-740. Epub 2022 Jan 24 doi: 10.1016/S0140-6736(22)00010-1. PMID: 35085502
Systemic lupus erythematosus and ocular involvement: an overview.
Dammacco R
Clin Exp Med 2018 May;18(2):135-149. Epub 2017 Dec 14 doi: 10.1007/s10238-017-0479-9. PMID: 29243035
Periventricular leukomalacia: an important cause of visual and ocular motility dysfunction in children.
Jacobson LK, Dutton GN
Surv Ophthalmol 2000 Jul-Aug;45(1):1-13. doi: 10.1016/s0039-6257(00)00134-x. PMID: 10946078

Therapy

Gene Editing for CEP290-Associated Retinal Degeneration.
Pierce EA, Aleman TS, Jayasundera KT, Ashimatey BS, Kim K, Rashid A, Jaskolka MC, Myers RL, Lam BL, Bailey ST, Comander JI, Lauer AK, Maguire AM, Pennesi ME
N Engl J Med 2024 Jun 6;390(21):1972-1984. Epub 2024 May 6 doi: 10.1056/NEJMoa2309915. PMID: 38709228Free PMC Article
Risk of ocular adverse events with aromatase inhibitors.
Feng ZX, Sriranganathan A, Lo C, Liu V, Maberley D, Etminan M
Can J Ophthalmol 2024 Oct;59(5):e431-e434. Epub 2023 Nov 3 doi: 10.1016/j.jcjo.2023.10.013. PMID: 37931898
Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Monés J, Singh RP, Ribeiro R, Wykoff CC; OAKS and DERBY study investigators
Lancet 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9. PMID: 37865470
Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials.
Heier JS, Khanani AM, Quezada Ruiz C, Basu K, Ferrone PJ, Brittain C, Figueroa MS, Lin H, Holz FG, Patel V, Lai TYY, Silverman D, Regillo C, Swaminathan B, Viola F, Cheung CMG, Wong TY; TENAYA and LUCERNE Investigators
Lancet 2022 Feb 19;399(10326):729-740. Epub 2022 Jan 24 doi: 10.1016/S0140-6736(22)00010-1. PMID: 35085502
Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial.
Nguyen QD, Merrill PT, Jaffe GJ, Dick AD, Kurup SK, Sheppard J, Schlaen A, Pavesio C, Cimino L, Van Calster J, Camez AA, Kwatra NV, Song AP, Kron M, Tari S, Brézin AP
Lancet 2016 Sep 17;388(10050):1183-92. Epub 2016 Aug 16 doi: 10.1016/S0140-6736(16)31339-3. PMID: 27542302

Prognosis

Risk of ocular adverse events with aromatase inhibitors.
Feng ZX, Sriranganathan A, Lo C, Liu V, Maberley D, Etminan M
Can J Ophthalmol 2024 Oct;59(5):e431-e434. Epub 2023 Nov 3 doi: 10.1016/j.jcjo.2023.10.013. PMID: 37931898
Pivotal trial of a deep-learning-based retinal biomarker (Reti-CVD) in the prediction of cardiovascular disease: data from CMERC-HI.
Lee CJ, Rim TH, Kang HG, Yi JK, Lee G, Yu M, Park SH, Hwang JT, Tham YC, Wong TY, Cheng CY, Kim DW, Kim SS, Park S
J Am Med Inform Assoc 2023 Dec 22;31(1):130-138. doi: 10.1093/jamia/ocad199. PMID: 37847669Free PMC Article
Childhood uveitis not associated with juvenile idiopathic arthritis: a national survey of incidence, management and visual outcomes.
Koay SY, Johnson M, Xing W, Foot B, MacEwen C, Dahlmann-Noor A, Thomas D
Eye (Lond) 2021 Sep;35(9):2573-2578. Epub 2020 Nov 16 doi: 10.1038/s41433-020-01267-2. PMID: 33199865Free PMC Article
Patient-Reported Complications after Intravitreal Injection and Their Predictive Factors.
Ramos MS, Xu LT, Singuri S, Castillo Tafur JC, Arepalli S, Ehlers JP, Kaiser PK, Singh RP, Rachitskaya AV, Srivastava SK, Sears JE, Schachat AP, Babiuch AS, Sharma S, Martin DF, Lowder CY, Singh AD, Yuan A, Nowacki AS
Ophthalmol Retina 2021 Jul;5(7):625-632. Epub 2020 Oct 12 doi: 10.1016/j.oret.2020.09.024. PMID: 33059077Free PMC Article
Periventricular leukomalacia: an important cause of visual and ocular motility dysfunction in children.
Jacobson LK, Dutton GN
Surv Ophthalmol 2000 Jul-Aug;45(1):1-13. doi: 10.1016/s0039-6257(00)00134-x. PMID: 10946078

Clinical prediction guides

Gene Editing for CEP290-Associated Retinal Degeneration.
Pierce EA, Aleman TS, Jayasundera KT, Ashimatey BS, Kim K, Rashid A, Jaskolka MC, Myers RL, Lam BL, Bailey ST, Comander JI, Lauer AK, Maguire AM, Pennesi ME
N Engl J Med 2024 Jun 6;390(21):1972-1984. Epub 2024 May 6 doi: 10.1056/NEJMoa2309915. PMID: 38709228Free PMC Article
LipiFlow for the treatment of dry eye disease.
Pucker AD, Yim TW, Rueff E, Ngo W, Tichenor AA, Conto JE
Cochrane Database Syst Rev 2024 Feb 5;2(2):CD015448. doi: 10.1002/14651858.CD015448.pub2. PMID: 38314898Free PMC Article
Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.
Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Monés J, Singh RP, Ribeiro R, Wykoff CC; OAKS and DERBY study investigators
Lancet 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9. PMID: 37865470
Vaccine-Associated Uveitis after COVID-19 Vaccination: Vaccine Adverse Event Reporting System Database Analysis.
Singh RB, Parmar UPS, Kahale F, Agarwal A, Tsui E
Ophthalmology 2023 Feb;130(2):179-186. Epub 2022 Aug 31 doi: 10.1016/j.ophtha.2022.08.027. PMID: 36055601Free PMC Article
Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial.
Nguyen QD, Merrill PT, Jaffe GJ, Dick AD, Kurup SK, Sheppard J, Schlaen A, Pavesio C, Cimino L, Van Calster J, Camez AA, Kwatra NV, Song AP, Kron M, Tari S, Brézin AP
Lancet 2016 Sep 17;388(10050):1183-92. Epub 2016 Aug 16 doi: 10.1016/S0140-6736(16)31339-3. PMID: 27542302

Recent systematic reviews

LipiFlow for the treatment of dry eye disease.
Pucker AD, Yim TW, Rueff E, Ngo W, Tichenor AA, Conto JE
Cochrane Database Syst Rev 2024 Feb 5;2(2):CD015448. doi: 10.1002/14651858.CD015448.pub2. PMID: 38314898Free PMC Article
Silicone hydrogel versus hydrogel soft contact lenses for differences in patient-reported eye comfort and safety.
Haworth K, Travis D, Leslie L, Fuller D, Pucker AD
Cochrane Database Syst Rev 2023 Sep 19;9(9):CD014791. doi: 10.1002/14651858.CD014791.pub2. PMID: 37724689Free PMC Article
Local tumor control and treatment related toxicity after plaque brachytherapy for uveal melanoma: A systematic review and a data pooled analysis.
Buonanno F, Conson M, de Almeida Ribeiro C, Oliviero C, Itta F, Liuzzi R, Pacelli R, Cella L, Clemente S
Radiother Oncol 2022 Jan;166:15-25. Epub 2021 Nov 11 doi: 10.1016/j.radonc.2021.11.007. PMID: 34774654
Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract surgery.
Maedel S, Evans JR, Harrer-Seely A, Findl O
Cochrane Database Syst Rev 2021 Aug 16;8(8):CD012516. doi: 10.1002/14651858.CD012516.pub2. PMID: 34398965Free PMC Article
Corneal collagen cross-linking for bacterial infectious keratitis.
Davis SA, Bovelle R, Han G, Kwagyan J
Cochrane Database Syst Rev 2020 Jun 17;6(6):CD013001. doi: 10.1002/14651858.CD013001.pub2. PMID: 32557558Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...