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Cervical Soft Tissue Neoplasm

MedGen UID:
308951
•Concept ID:
C1516432
•
Neoplastic Process
Synonym: Cervical Soft Tissue Tumor

Definition

A benign or malignant mesenchymal neoplasm of the cervix. Representative examples include rhabdomyoma, alveolar soft part sarcoma, and AIDS-related Kaposi sarcoma. [from NCI]

Professional guidelines

PubMed

Advances in treatment of alveolar soft part sarcoma: an updated review.
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M
Oncologist 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. PMID: 35983951Free PMC Article
Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA
J Natl Compr Canc Netw 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035. PMID: 35830886Free PMC Article

Recent clinical studies

Etiology

Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck.
Baranov E, Hornick JL
Head Neck Pathol 2020 Mar;14(1):43-58. Epub 2020 Jan 16 doi: 10.1007/s12105-019-01104-3. PMID: 31950474Free PMC Article
Soft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck.
Tran NA, Guenette JP, Jagannathan J
Head Neck Pathol 2020 Mar;14(1):132-143. Epub 2020 Jan 16 doi: 10.1007/s12105-019-01102-5. PMID: 31950470Free PMC Article
Vascular Anomalies.
Johnson AB, Richter GT
Clin Perinatol 2018 Dec;45(4):737-749. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.010. PMID: 30396415
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428
Lipoblastoma.
Chun YS, Kim WK, Park KW, Lee SC, Jung SE
J Pediatr Surg 2001 Jun;36(6):905-7. doi: 10.1053/jpsu.2001.23969. PMID: 11381423

Diagnosis

Advances in treatment of alveolar soft part sarcoma: an updated review.
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA
J Natl Compr Canc Netw 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035. PMID: 35830886Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Soft Tissue Tumors.
Jo VY, Demicco EG
Head Neck Pathol 2022 Mar;16(1):87-100. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01425-w. PMID: 35312984Free PMC Article
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426
Myofibrosarcoma.
Fisher C
Virchows Arch 2004 Sep;445(3):215-23. Epub 2004 Jun 2 doi: 10.1007/s00428-004-1038-9. PMID: 15173943

Therapy

Imaging of the post-treatment neck.
Gillespie J
Clin Radiol 2020 Oct;75(10):794.e7-794.e17. Epub 2020 Jul 18 doi: 10.1016/j.crad.2020.06.011. PMID: 32690240
Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study.
Penel N, Bui BN, Bay JO, Cupissol D, Ray-Coquard I, Piperno-Neumann S, Kerbrat P, Fournier C, Taieb S, Jimenez M, Isambert N, Peyrade F, Chevreau C, Bompas E, Brain EG, Blay JY
J Clin Oncol 2008 Nov 10;26(32):5269-74. Epub 2008 Sep 22 doi: 10.1200/JCO.2008.17.3146. PMID: 18809609
Microenvironment-induced cancer metastasis.
Rofstad EK
Int J Radiat Biol 2000 May;76(5):589-605. doi: 10.1080/095530000138259. PMID: 10866281
Docetaxel.
Cortes JE, Pazdur R
J Clin Oncol 1995 Oct;13(10):2643-55. doi: 10.1200/JCO.1995.13.10.2643. PMID: 7595719
Infusion-embolization.
Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

Prognosis

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Soft Tissue Tumors.
Jo VY, Demicco EG
Head Neck Pathol 2022 Mar;16(1):87-100. Epub 2022 Mar 21 doi: 10.1007/s12105-022-01425-w. PMID: 35312984Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Soft-tissue sarcoma.
Gilbert NF, Cannon CP, Lin PP, Lewis VO
J Am Acad Orthop Surg 2009 Jan;17(1):40-7. doi: 10.5435/00124635-200901000-00006. PMID: 19136426
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428
Angiosarcoma: current review.
Fedok FG, Levin RJ, Maloney ME, Tipirneni K
Am J Otolaryngol 1999 Jul-Aug;20(4):223-31. doi: 10.1016/s0196-0709(99)90004-2. PMID: 10442774

Clinical prediction guides

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Overview of the 8th Edition TNM Classification for Head and Neck Cancer.
Huang SH, O'Sullivan B
Curr Treat Options Oncol 2017 Jul;18(7):40. doi: 10.1007/s11864-017-0484-y. PMID: 28555375
Angiosarcoma.
Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ
Lancet Oncol 2010 Oct;11(10):983-91. Epub 2010 May 25 doi: 10.1016/S1470-2045(10)70023-1. PMID: 20537949
Metallothioneins and cancer.
Eckschlager T, Adam V, Hrabeta J, Figova K, Kizek R
Curr Protein Pept Sci 2009 Aug;10(4):360-75. doi: 10.2174/138920309788922243. PMID: 19689357
Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.
Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW
Am J Surg Pathol 2005 Dec;29(12):1558-75. doi: 10.1097/01.pas.0000173232.22117.37. PMID: 16327428

Recent systematic reviews

Hyperbaric oxygen therapy for late radiation tissue injury.
Lin ZC, Bennett MH, Hawkins GC, Azzopardi CP, Feldmeier J, Smee R, Milross C
Cochrane Database Syst Rev 2023 Aug 15;8(8):CD005005. doi: 10.1002/14651858.CD005005.pub5. PMID: 37585677Free PMC Article
Oral radiation-induced sarcomas: Systematic review.
de Souza LL, Pontes HAR, Santos-Silva AR, Fernandes LA, Batista LAL, Lopes MA, Khan W, Pontes FSC
Head Neck 2020 Sep;42(9):2660-2668. Epub 2020 Apr 28 doi: 10.1002/hed.26176. PMID: 32343457
Denture use and osteoradionecrosis following radiotherapy for head and neck cancer: A systematic review.
Abed H, Burke M, Scambler S, Scott SE
Gerodontology 2020 Jun;37(2):102-109. Epub 2019 Dec 30 doi: 10.1111/ger.12456. PMID: 31886587
Radiation-Associated Sarcoma of the Neck: Case Series and Systematic Review.
Williams L, Tmanova L, Mydlarz WK, Page B, Richmon JD, Quon H, Schmitt NC
Ann Otol Rhinol Laryngol 2018 Oct;127(10):735-740. Epub 2018 Jul 26 doi: 10.1177/0003489418789966. PMID: 30047787
Liposarcoma of Hypopharynx and Esophagus: a Unique Entity?
Riva G, Sensini M, Corvino A, Garzaro M, Pecorari G
J Gastrointest Cancer 2016 Jun;47(2):135-42. doi: 10.1007/s12029-016-9808-6. PMID: 26875081

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