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Endocervical Undifferentiated Sarcoma

MedGen UID:
311409
•Concept ID:
C1519782
•
Neoplastic Process
Synonyms: Undifferentiated Endocervical Sarcoma; Undifferentiated Sarcoma of the Endocervix

Definition

A high grade undifferentiated sarcoma that arises from the endocervix. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndocervical Undifferentiated Sarcoma

Professional guidelines

PubMed

Sarcomas of uterine cervix: clinicopathological features, treatment, and outcome.
Khosla D, Gupta R, Srinivasan R, Patel FD, Rajwanshi A
Int J Gynecol Cancer 2012 Jul;22(6):1026-30. doi: 10.1097/IGC.0b013e31825a97f6. PMID: 22740005

Recent clinical studies

Etiology

Sarcomas of uterine cervix: clinicopathological features, treatment, and outcome.
Khosla D, Gupta R, Srinivasan R, Patel FD, Rajwanshi A
Int J Gynecol Cancer 2012 Jul;22(6):1026-30. doi: 10.1097/IGC.0b013e31825a97f6. PMID: 22740005

Diagnosis

SMARCB1 (INI1) Deficient Tumours of the Uterine Cervix: Report of Two Cases, Including One Associated With an NTRK Fusion.
Razack R, Butt JL, Hostein I, Velasco V, Croce S, Olory C, Fu L, Foulkes WD, McCluggage WG
Int J Gynecol Pathol 2024 Sep 1;43(5):464-471. Epub 2024 Jan 22 doi: 10.1097/PGP.0000000000001014. PMID: 38289183
Recently described entities in the gynaecological tract.
Reyes MC, Cooper K
Pathology 2015 Aug;47(5):414-22. doi: 10.1097/PAT.0000000000000277. PMID: 26126047
Sarcomas of uterine cervix: clinicopathological features, treatment, and outcome.
Khosla D, Gupta R, Srinivasan R, Patel FD, Rajwanshi A
Int J Gynecol Cancer 2012 Jul;22(6):1026-30. doi: 10.1097/IGC.0b013e31825a97f6. PMID: 22740005
Uterine adenosarcoma with sarcomatous overgrowth: a case report with cytology of overgrown poorly differentiated sarcoma and immunohistochemical identification of epithelial microinvasion.
Nagai Y, Kishimoto T, Kato K, Ozaki D, Kondo F, Kobayashi A, Shimizu H, Ishikura H
Int J Gynecol Cancer 2002 Sep-Oct;12(5):501-5. doi: 10.1046/j.1525-1438.2002.01129.x. PMID: 12366670
Uterine carcinosarcoma with melanocytic differentiation.
Amant F, Moerman P, Davel GH, De Vos R, Vergote I, Lindeque BG, de Jonge E
Int J Gynecol Pathol 2001 Apr;20(2):186-90. doi: 10.1097/00004347-200104000-00012. PMID: 11293166

Prognosis

Uterine adenosarcoma with sarcomatous overgrowth: a case report with cytology of overgrown poorly differentiated sarcoma and immunohistochemical identification of epithelial microinvasion.
Nagai Y, Kishimoto T, Kato K, Ozaki D, Kondo F, Kobayashi A, Shimizu H, Ishikura H
Int J Gynecol Cancer 2002 Sep-Oct;12(5):501-5. doi: 10.1046/j.1525-1438.2002.01129.x. PMID: 12366670

Clinical prediction guides

Uterine carcinosarcoma with melanocytic differentiation.
Amant F, Moerman P, Davel GH, De Vos R, Vergote I, Lindeque BG, de Jonge E
Int J Gynecol Pathol 2001 Apr;20(2):186-90. doi: 10.1097/00004347-200104000-00012. PMID: 11293166

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