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Myelodysplastic/Myeloproliferative Neoplasm Post Cytotoxic Therapy

MedGen UID:
417377
•Concept ID:
C2826148
•
Neoplastic Process
Synonyms: Therapy-Related Myelodysplastic/Myeloproliferative Disease; Therapy-Related Myelodysplastic/Myeloproliferative Neoplasm

Definition

A myelodysplastic/myeloproliferative neoplasm arising as a result of the mutagenic effect of chemotherapy agents and/or radiation that are used for the treatment of neoplastic or non-neoplastic disorders. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyelodysplastic/Myeloproliferative Neoplasm Post Cytotoxic Therapy

Professional guidelines

PubMed

Decitabine-based treatment strategy improved the outcome of HSCT in JMML: a retrospective cohort study.
Peng Z, Gao J, Huang L, He Y, Tang H, Zong S, Pei Y, Pei F, Ge J, Liu X, Yue L, Zhou J, Li X, Yue D, Chen Y, Chen C, Wu X, Feng X, Li C
Front Immunol 2024;15:1426640. Epub 2024 Aug 26 doi: 10.3389/fimmu.2024.1426640. PMID: 39253078Free PMC Article

Recent clinical studies

Therapy

Decitabine-based treatment strategy improved the outcome of HSCT in JMML: a retrospective cohort study.
Peng Z, Gao J, Huang L, He Y, Tang H, Zong S, Pei Y, Pei F, Ge J, Liu X, Yue L, Zhou J, Li X, Yue D, Chen Y, Chen C, Wu X, Feng X, Li C
Front Immunol 2024;15:1426640. Epub 2024 Aug 26 doi: 10.3389/fimmu.2024.1426640. PMID: 39253078Free PMC Article
Defective mitogen-induced cellular cytotoxicity in myelodysplastic syndromes. Recovery after alpha-interferon administration.
Eliopoulos G, Constantopoulou M, Coulocheri S, Vaiopoulos G, Eliopoulos A, Yataganas X
Anticancer Res 1991 Mar-Apr;11(2):685-9. PMID: 2064322

Prognosis

Decitabine-based treatment strategy improved the outcome of HSCT in JMML: a retrospective cohort study.
Peng Z, Gao J, Huang L, He Y, Tang H, Zong S, Pei Y, Pei F, Ge J, Liu X, Yue L, Zhou J, Li X, Yue D, Chen Y, Chen C, Wu X, Feng X, Li C
Front Immunol 2024;15:1426640. Epub 2024 Aug 26 doi: 10.3389/fimmu.2024.1426640. PMID: 39253078Free PMC Article

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