U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Erythema induratum

MedGen UID:
41857
Concept ID:
C0014741
Disease or Syndrome
Synonyms: Bazin Disease; Bazin's Disease; Bazins Disease; Disease, Bazin; Disease, Bazin's; Erythema Induratum; Tuberculosis Cutis Indurativa
SNOMED CT: Tuberculosis cutis indurativa (11354005); Tuberculous erythema induratum (11354005); Tuberculous Bazin's disease (11354005); Bazin's disease (11354005); Erythema induratum (2028007)

Definition

A type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVErythema induratum

Professional guidelines

PubMed

Kaul S, Jakhar D, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1107-1119. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.064. PMID: 35149148
Gilchrist H, Patterson JW
Dermatol Ther 2010 Jul-Aug;23(4):320-7. doi: 10.1111/j.1529-8019.2010.01332.x. PMID: 20666819
Barbagallo J, Tager P, Ingleton R, Hirsch RJ, Weinberg JM
Am J Clin Dermatol 2002;3(5):319-28. doi: 10.2165/00128071-200203050-00004. PMID: 12069638

Recent clinical studies

Etiology

Llamas-Velasco M, Fraga J, Sánchez-Schmidt JM, Fernández-Figueras M, Gallardo F, Rütten A, Kempf W
Am J Dermatopathol 2020 Oct;42(10):717-730. doi: 10.1097/DAD.0000000000001597. PMID: 32956080
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Chan MP
Arch Pathol Lab Med 2014 Oct;138(10):1337-43. doi: 10.5858/arpa.2014-0270-CC. PMID: 25268197
Ferrara G, Stefanato CM, Gianotti R, Kubba A, Annessi G
G Ital Dermatol Venereol 2013 Aug;148(4):387-94. PMID: 23900160
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930

Diagnosis

Kaul S, Kaur I, Mehta S, Singal A
J Am Acad Dermatol 2023 Dec;89(6):1091-1103. Epub 2022 Feb 8 doi: 10.1016/j.jaad.2021.12.063. PMID: 35149149
Chen Q, Chen W, Hao F
Clin Dermatol 2019 May-Jun;37(3):192-199. Epub 2019 Jan 11 doi: 10.1016/j.clindermatol.2019.01.008. PMID: 31178102
Wick MR
Semin Diagn Pathol 2017 May;34(3):261-272. Epub 2016 Dec 27 doi: 10.1053/j.semdp.2016.12.004. PMID: 28129926
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Requena L, Requena C
Dermatol Online J 2002 Jun;8(1):4. PMID: 12165214

Therapy

Llamas-Velasco M, Fraga J, Sánchez-Schmidt JM, Fernández-Figueras M, Gallardo F, Rütten A, Kempf W
Am J Dermatopathol 2020 Oct;42(10):717-730. doi: 10.1097/DAD.0000000000001597. PMID: 32956080
Morita TCAB, Trés GFS, García MSC, Halpern I, Criado PR, de Carvalho JF
Adv Rheumatol 2019 Aug 1;59(1):35. doi: 10.1186/s42358-019-0077-5. PMID: 31370889
Chen Q, Chen W, Hao F
Clin Dermatol 2019 May-Jun;37(3):192-199. Epub 2019 Jan 11 doi: 10.1016/j.clindermatol.2019.01.008. PMID: 31178102
Ribeiro R, Patrício C, Pais da Silva F, Silva PE
BMJ Case Rep 2016 Mar 4;2016 doi: 10.1136/bcr-2015-213585. PMID: 26944370Free PMC Article
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930

Prognosis

Connors WJ, Fisher DA, Kunimoto DY, Jarand JM
BMC Infect Dis 2019 Jan 29;19(1):97. doi: 10.1186/s12879-019-3737-5. PMID: 30696400Free PMC Article
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Motswaledi HM, Schulz EJ
Int J Dermatol 2006 Nov;45(11):1337-40. doi: 10.1111/j.1365-4632.2006.02763.x. PMID: 17076720
Requena L, Requena C
Dermatol Online J 2002 Jun;8(1):4. PMID: 12165214
Barbagallo J, Tager P, Ingleton R, Hirsch RJ, Weinberg JM
Am J Clin Dermatol 2002;3(5):319-28. doi: 10.2165/00128071-200203050-00004. PMID: 12069638

Clinical prediction guides

Llamas-Velasco M, Fraga J, Sánchez-Schmidt JM, Fernández-Figueras M, Gallardo F, Rütten A, Kempf W
Am J Dermatopathol 2020 Oct;42(10):717-730. doi: 10.1097/DAD.0000000000001597. PMID: 32956080
Sethuraman G, Ramesh V
Pediatr Dermatol 2013 Jan-Feb;30(1):7-16. Epub 2012 Nov 22 doi: 10.1111/j.1525-1470.2012.01794.x. PMID: 23173930
Patel LM, Lambert PJ, Gagna CE, Maghari A, Lambert WC
Clin Dermatol 2011 Sep-Oct;29(5):511-22. doi: 10.1016/j.clindermatol.2011.01.019. PMID: 21855727
White WL, Wieselthier JS, Hitchcock MG
Semin Cutan Med Surg 1996 Dec;15(4):278-99. doi: 10.1016/s1085-5629(96)80042-3. PMID: 9069596
Harris RB, Duncan SC, Ecker RI, Winkelmann RK
Arch Dermatol 1979 Apr;115(4):442-3. PMID: 434865

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...