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Gastrointestinal infarctions

MedGen UID:
463581
•Concept ID:
C3152231
•
Finding; Pathologic Function
Synonyms: Death of digestive organ tissue due to poor blood supply; GI infarctions
 
HPO: HP:0005244

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastrointestinal infarctions

Conditions with this feature

Malignant atrophic papulosis
MedGen UID:
113138
•Concept ID:
C0221011
•
Disease or Syndrome
Malignant atrophic papulosis (MAP) is a rare, chronic, thrombo-obliterative vasculopathy characterized by papular skin lesions with central porcelain-white atrophy and a surrounding teleangiectatic rim. Systemic lesions may affect the gastrointestinal tract and the central nervous system (CNS) and are potentially lethal.
See: Condition Record
Malignant atrophic papulosis

Professional guidelines

PubMed

Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.
Shi Q, Nong K, Vandvik PO, Guyatt GH, Schnell O, Rydén L, Marx N, Brosius FC 3rd, Mustafa RA, Agarwal A, Zou X, Mao Y, Asadollahifar A, Chowdhury SR, Zhai C, Gupta S, Gao Y, Lima JP, Numata K, Qiao Z, Fan Q, Yang Q, Jin Y, Ge L, Yang Q, Zhu H, Yang F, Chen Z, Lu X, He S, Chen X, Lyu X, An X, Chen Y, Hao Q, Standl E, Siemieniuk R, Agoritsas T, Tian H, Li S
BMJ 2023 Apr 6;381:e074068. doi: 10.1136/bmj-2022-074068. PMID: 37024129Free PMC Article
The Risks and Benefits of Long-term Use of Proton Pump Inhibitors: Expert Review and Best Practice Advice From the American Gastroenterological Association.
Freedberg DE, Kim LS, Yang YX
Gastroenterology 2017 Mar;152(4):706-715. doi: 10.1053/j.gastro.2017.01.031. PMID: 28257716
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY.
Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines
Endocr Pract 2016 Jul;22 Suppl 3:1-203. Epub 2016 May 24 doi: 10.4158/EP161365.GL. PMID: 27219496

Recent clinical studies

Etiology

Traditional Chinese Medicine Compound (Tongxinluo) and Clinical Outcomes of Patients With Acute Myocardial Infarction: The CTS-AMI Randomized Clinical Trial.
Yang Y, Li X, Chen G, Xian Y, Zhang H, Wu Y, Yang Y, Wu J, Wang C, He S, Wang Z, Wang Y, Wang Z, Liu H, Wang X, Zhang M, Zhang J, Li J, An T, Guan H, Li L, Shang M, Yao C, Han Y, Zhang B, Gao R, Peterson ED; CTS-AMI Investigators
JAMA 2023 Oct 24;330(16):1534-1545. doi: 10.1001/jama.2023.19524. PMID: 37874574Free PMC Article
Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
Nemet I, Li XS, Haghikia A, Li L, Wilcox J, Romano KA, Buffa JA, Witkowski M, Demuth I, König M, Steinhagen-Thiessen E, Bäckhed F, Fischbach MA, Tang WHW, Landmesser U, Hazen SL
Eur Heart J 2023 Aug 22;44(32):3085-3096. doi: 10.1093/eurheartj/ehad333. PMID: 37342006Free PMC Article
Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Jaén CR, Krist AH, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Tseng CW, Wong JB
JAMA 2022 Apr 26;327(16):1577-1584. doi: 10.1001/jama.2022.4983. PMID: 35471505
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Gaziano JM, Brotons C, Coppolecchia R, Cricelli C, Darius H, Gorelick PB, Howard G, Pearson TA, Rothwell PM, Ruilope LM, Tendera M, Tognoni G; ARRIVE Executive Committee
Lancet 2018 Sep 22;392(10152):1036-1046. Epub 2018 Aug 26 doi: 10.1016/S0140-6736(18)31924-X. PMID: 30158069Free PMC Article
Aspirin for Primary Prevention.
Richman IB, Owens DK
Med Clin North Am 2017 Jul;101(4):713-724. doi: 10.1016/j.mcna.2017.03.004. PMID: 28577622

Diagnosis

Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality.
Nemet I, Li XS, Haghikia A, Li L, Wilcox J, Romano KA, Buffa JA, Witkowski M, Demuth I, König M, Steinhagen-Thiessen E, Bäckhed F, Fischbach MA, Tang WHW, Landmesser U, Hazen SL
Eur Heart J 2023 Aug 22;44(32):3085-3096. doi: 10.1093/eurheartj/ehad333. PMID: 37342006Free PMC Article
Atrophic Papulosis.
Robert M, Hot A
Dermatology 2023;239(2):177-187. Epub 2022 Nov 9 doi: 10.1159/000526789. PMID: 36353773
Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Jaén CR, Krist AH, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Tseng CW, Wong JB
JAMA 2022 Apr 26;327(16):1577-1584. doi: 10.1001/jama.2022.4983. PMID: 35471505
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
HALT-IT Trial Collaborators
Lancet 2020 Jun 20;395(10241):1927-1936. doi: 10.1016/S0140-6736(20)30848-5. PMID: 32563378Free PMC Article
Cardiovascular Safety of Tocilizumab Versus Etanercept in Rheumatoid Arthritis: A Randomized Controlled Trial.
Giles JT, Sattar N, Gabriel S, Ridker PM, Gay S, Warne C, Musselman D, Brockwell L, Shittu E, Klearman M, Fleming TR
Arthritis Rheumatol 2020 Jan;72(1):31-40. doi: 10.1002/art.41095. PMID: 31469238

Therapy

Traditional Chinese Medicine Compound (Tongxinluo) and Clinical Outcomes of Patients With Acute Myocardial Infarction: The CTS-AMI Randomized Clinical Trial.
Yang Y, Li X, Chen G, Xian Y, Zhang H, Wu Y, Yang Y, Wu J, Wang C, He S, Wang Z, Wang Y, Wang Z, Liu H, Wang X, Zhang M, Zhang J, Li J, An T, Guan H, Li L, Shang M, Yao C, Han Y, Zhang B, Gao R, Peterson ED; CTS-AMI Investigators
JAMA 2023 Oct 24;330(16):1534-1545. doi: 10.1001/jama.2023.19524. PMID: 37874574Free PMC Article
Transfusion thresholds for guiding red blood cell transfusion.
Carson JL, Stanworth SJ, Dennis JA, Trivella M, Roubinian N, Fergusson DA, Triulzi D, Dorée C, Hébert PC
Cochrane Database Syst Rev 2021 Dec 21;12(12):CD002042. doi: 10.1002/14651858.CD002042.pub5. PMID: 34932836Free PMC Article
Mucormycosis.
Reid G, Lynch JP 3rd, Fishbein MC, Clark NM
Semin Respir Crit Care Med 2020 Feb;41(1):99-114. Epub 2020 Jan 30 doi: 10.1055/s-0039-3401992. PMID: 32000287
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Gaziano JM, Brotons C, Coppolecchia R, Cricelli C, Darius H, Gorelick PB, Howard G, Pearson TA, Rothwell PM, Ruilope LM, Tendera M, Tognoni G; ARRIVE Executive Committee
Lancet 2018 Sep 22;392(10152):1036-1046. Epub 2018 Aug 26 doi: 10.1016/S0140-6736(18)31924-X. PMID: 30158069Free PMC Article
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY.
Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines
Endocr Pract 2016 Jul;22 Suppl 3:1-203. Epub 2016 May 24 doi: 10.4158/EP161365.GL. PMID: 27219496

Prognosis

Traditional Chinese Medicine Compound (Tongxinluo) and Clinical Outcomes of Patients With Acute Myocardial Infarction: The CTS-AMI Randomized Clinical Trial.
Yang Y, Li X, Chen G, Xian Y, Zhang H, Wu Y, Yang Y, Wu J, Wang C, He S, Wang Z, Wang Y, Wang Z, Liu H, Wang X, Zhang M, Zhang J, Li J, An T, Guan H, Li L, Shang M, Yao C, Han Y, Zhang B, Gao R, Peterson ED; CTS-AMI Investigators
JAMA 2023 Oct 24;330(16):1534-1545. doi: 10.1001/jama.2023.19524. PMID: 37874574Free PMC Article
Gut microbiota combined with metabolites reveals unique features of acute myocardial infarction patients different from stable coronary artery disease.
Dong C, Yang Y, Wang Y, Hu X, Wang Q, Gao F, Sun S, Liu Q, Li L, Liu J, Tang Y, Zhang S, Wu C, Zhu H
J Adv Res 2023 Apr;46:101-112. Epub 2022 Jun 21 doi: 10.1016/j.jare.2022.06.008. PMID: 35750287Free PMC Article
Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial.
Anand SS, Bosch J, Eikelboom JW, Connolly SJ, Diaz R, Widimsky P, Aboyans V, Alings M, Kakkar AK, Keltai K, Maggioni AP, Lewis BS, Störk S, Zhu J, Lopez-Jaramillo P, O'Donnell M, Commerford PJ, Vinereanu D, Pogosova N, Ryden L, Fox KAA, Bhatt DL, Misselwitz F, Varigos JD, Vanassche T, Avezum AA, Chen E, Branch K, Leong DP, Bangdiwala SI, Hart RG, Yusuf S; COMPASS Investigators
Lancet 2018 Jan 20;391(10117):219-229. Epub 2017 Nov 10 doi: 10.1016/S0140-6736(17)32409-1. PMID: 29132880
Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality.
O'Keefe JH, Bhatti SK, Patil HR, DiNicolantonio JJ, Lucan SC, Lavie CJ
J Am Coll Cardiol 2013 Sep 17;62(12):1043-1051. Epub 2013 Jul 17 doi: 10.1016/j.jacc.2013.06.035. PMID: 23871889
Results of the CAPRIE trial: efficacy and safety of clopidogrel. Clopidogrel versus aspirin in patients at risk of ischaemic events.
Creager MA
Vasc Med 1998;3(3):257-60. doi: 10.1177/1358836X9800300314. PMID: 9892520

Clinical prediction guides

Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease.
Lewis CV, Taylor WR
Am J Physiol Heart Circ Physiol 2020 Dec 1;319(6):H1227-H1233. Epub 2020 Sep 28 doi: 10.1152/ajpheart.00612.2020. PMID: 32986965Free PMC Article
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.
HALT-IT Trial Collaborators
Lancet 2020 Jun 20;395(10241):1927-1936. doi: 10.1016/S0140-6736(20)30848-5. PMID: 32563378Free PMC Article
Safety of Oral Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Osteoarthritis: What Does the Literature Say?
Cooper C, Chapurlat R, Al-Daghri N, Herrero-Beaumont G, Bruyère O, Rannou F, Roth R, Uebelhart D, Reginster JY
Drugs Aging 2019 Apr;36(Suppl 1):15-24. doi: 10.1007/s40266-019-00660-1. PMID: 31073921Free PMC Article
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Gaziano JM, Brotons C, Coppolecchia R, Cricelli C, Darius H, Gorelick PB, Howard G, Pearson TA, Rothwell PM, Ruilope LM, Tendera M, Tognoni G; ARRIVE Executive Committee
Lancet 2018 Sep 22;392(10152):1036-1046. Epub 2018 Aug 26 doi: 10.1016/S0140-6736(18)31924-X. PMID: 30158069Free PMC Article
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.
Coxib and traditional NSAID Trialists' (CNT) Collaboration, Bhala N, Emberson J, Merhi A, Abramson S, Arber N, Baron JA, Bombardier C, Cannon C, Farkouh ME, FitzGerald GA, Goss P, Halls H, Hawk E, Hawkey C, Hennekens C, Hochberg M, Holland LE, Kearney PM, Laine L, Lanas A, Lance P, Laupacis A, Oates J, Patrono C, Schnitzer TJ, Solomon S, Tugwell P, Wilson K, Wittes J, Baigent C
Lancet 2013 Aug 31;382(9894):769-79. Epub 2013 May 30 doi: 10.1016/S0140-6736(13)60900-9. PMID: 23726390Free PMC Article

Recent systematic reviews

Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.
Shi Q, Nong K, Vandvik PO, Guyatt GH, Schnell O, Rydén L, Marx N, Brosius FC 3rd, Mustafa RA, Agarwal A, Zou X, Mao Y, Asadollahifar A, Chowdhury SR, Zhai C, Gupta S, Gao Y, Lima JP, Numata K, Qiao Z, Fan Q, Yang Q, Jin Y, Ge L, Yang Q, Zhu H, Yang F, Chen Z, Lu X, He S, Chen X, Lyu X, An X, Chen Y, Hao Q, Standl E, Siemieniuk R, Agoritsas T, Tian H, Li S
BMJ 2023 Apr 6;381:e074068. doi: 10.1136/bmj-2022-074068. PMID: 37024129Free PMC Article
Transfusion thresholds for guiding red blood cell transfusion.
Carson JL, Stanworth SJ, Dennis JA, Trivella M, Roubinian N, Fergusson DA, Triulzi D, Dorée C, Hébert PC
Cochrane Database Syst Rev 2021 Dec 21;12(12):CD002042. doi: 10.1002/14651858.CD002042.pub5. PMID: 34932836Free PMC Article
Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.
Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodríguez AF, González-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Díaz González-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM
BMJ 2021 Jan 13;372:m4573. doi: 10.1136/bmj.m4573. PMID: 33441402Free PMC Article
Aspirin for Primary Prevention of Cardiovascular Events.
Abdelaziz HK, Saad M, Pothineni NVK, Megaly M, Potluri R, Saleh M, Kon DLC, Roberts DH, Bhatt DL, Aronow HD, Abbott JD, Mehta JL
J Am Coll Cardiol 2019 Jun 18;73(23):2915-2929. doi: 10.1016/j.jacc.2019.03.501. PMID: 31196447
Long-term Systemic Corticosteroid Exposure: A Systematic Literature Review.
Rice JB, White AG, Scarpati LM, Wan G, Nelson WW
Clin Ther 2017 Nov;39(11):2216-2229. Epub 2017 Oct 19 doi: 10.1016/j.clinthera.2017.09.011. PMID: 29055500

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    Clinical resources

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