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Associated pulmonary arterial hypertension

MedGen UID:
473476
Concept ID:
C1701938
Disease or Syndrome
Synonym: Associated Pulmonary Arterial Hypertension
SNOMED CT: Associated pulmonary arterial hypertension (697902002)

Definition

Pulmonary hypertension that results from another disorder (e.g., connective tissue disorder). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAssociated pulmonary arterial hypertension

Professional guidelines

PubMed

Kularatne M, Boucly A, Savale L, Solinas S, Cheron C, Roche A, Jevnikar M, Jaïs X, Montani D, Humbert M, Sitbon O
Expert Opin Pharmacother 2023 Sep-Dec;24(18):2101-2115. Epub 2024 Jan 5 doi: 10.1080/14656566.2023.2273395. PMID: 37869785
Attanasio U, Cuomo A, Pirozzi F, Loffredo S, Abete P, Petretta M, Marone G, Bonaduce D, De Paulis A, Rossi FW, Tocchetti CG, Mercurio V
Int J Mol Sci 2020 Jun 22;21(12) doi: 10.3390/ijms21124430. PMID: 32580360Free PMC Article
Gomez-Arroyo J, Sandoval J, Simon MA, Dominguez-Cano E, Voelkel NF, Bogaard HJ
Ann Am Thorac Soc 2014 Sep;11(7):1101-15. doi: 10.1513/AnnalsATS.201312-425FR. PMID: 25079379

Recent clinical studies

Etiology

Kularatne M, Boucly A, Savale L, Solinas S, Cheron C, Roche A, Jevnikar M, Jaïs X, Montani D, Humbert M, Sitbon O
Expert Opin Pharmacother 2023 Sep-Dec;24(18):2101-2115. Epub 2024 Jan 5 doi: 10.1080/14656566.2023.2273395. PMID: 37869785
Simpson CE, Ambade AS, Harlan R, Roux A, Aja S, Graham D, Shah AA, Hummers LK, Hemnes AR, Leopold JA, Horn EM, Berman-Rosenzweig ES, Grunig G, Aldred MA, Barnard J, Comhair SAA, Tang WHW, Griffiths M, Rischard F, Frantz RP, Erzurum SC, Beck GJ, Hill NS, Mathai SC, Hassoun PM, Damico RL; the PVDOMICS Study Group
Am J Physiol Lung Cell Mol Physiol 2023 Nov 1;325(5):L617-L627. Epub 2023 Oct 3 doi: 10.1152/ajplung.00177.2023. PMID: 37786941Free PMC Article
Zhang Q, Zhu F, Shi G, Hu C, Zhang W, Huang P, Zhu C, Gu H, Yang D, Li Q, Niu Y, Chen H, Ma R, Pan Z, Miao H, Zhang X, Li G, Tang Y, Qiao G, Yan Y, Zhu Z, Zhang H, Han F, Li Y, Lin J, Chen H
Circulation 2023 Feb 14;147(7):549-561. Epub 2023 Feb 13 doi: 10.1161/CIRCULATIONAHA.122.057987. PMID: 36780387
Ramirez RL 3rd, Perez VJ, Zamanian RT
Curr Opin Pulm Med 2018 Sep;24(5):416-424. doi: 10.1097/MCP.0000000000000513. PMID: 30036313Free PMC Article
McGee M, Whitehead N, Martin J, Collins N
Clin Toxicol (Phila) 2018 Sep;56(9):801-809. Epub 2018 Mar 6 doi: 10.1080/15563650.2018.1447119. PMID: 29508628

Diagnosis

Charoenpong P, Hall NM, Keller CM, Ram AK, Murnane KS, Goeders NE, Dhillon NK, Walter RE
Chest 2024 Jun;165(6):1518-1533. Epub 2024 Jan 9 doi: 10.1016/j.chest.2024.01.014. PMID: 38211700Free PMC Article
Simpson CE, Ambade AS, Harlan R, Roux A, Aja S, Graham D, Shah AA, Hummers LK, Hemnes AR, Leopold JA, Horn EM, Berman-Rosenzweig ES, Grunig G, Aldred MA, Barnard J, Comhair SAA, Tang WHW, Griffiths M, Rischard F, Frantz RP, Erzurum SC, Beck GJ, Hill NS, Mathai SC, Hassoun PM, Damico RL; the PVDOMICS Study Group
Am J Physiol Lung Cell Mol Physiol 2023 Nov 1;325(5):L617-L627. Epub 2023 Oct 3 doi: 10.1152/ajplung.00177.2023. PMID: 37786941Free PMC Article
Zhang Q, Zhu F, Shi G, Hu C, Zhang W, Huang P, Zhu C, Gu H, Yang D, Li Q, Niu Y, Chen H, Ma R, Pan Z, Miao H, Zhang X, Li G, Tang Y, Qiao G, Yan Y, Zhu Z, Zhang H, Han F, Li Y, Lin J, Chen H
Circulation 2023 Feb 14;147(7):549-561. Epub 2023 Feb 13 doi: 10.1161/CIRCULATIONAHA.122.057987. PMID: 36780387
Sanges S, Rice L, Tu L, Valenzi E, Cracowski JL, Montani D, Mantero JC, Ternynck C, Marot G, Bujor AM, Hachulla E, Launay D, Humbert M, Guignabert C, Lafyatis R
Ann Rheum Dis 2023 Mar;82(3):365-373. Epub 2022 Dec 5 doi: 10.1136/ard-2022-223237. PMID: 36600187Free PMC Article
Basyal B, Jarrett H, Barnett CF
Can J Cardiol 2019 Mar;35(3):288-298. doi: 10.1016/j.cjca.2019.01.005. PMID: 30825951

Therapy

Charoenpong P, Hall NM, Keller CM, Ram AK, Murnane KS, Goeders NE, Dhillon NK, Walter RE
Chest 2024 Jun;165(6):1518-1533. Epub 2024 Jan 9 doi: 10.1016/j.chest.2024.01.014. PMID: 38211700Free PMC Article
McGee M, Whitehead N, Martin J, Collins N
Clin Toxicol (Phila) 2018 Sep;56(9):801-809. Epub 2018 Mar 6 doi: 10.1080/15563650.2018.1447119. PMID: 29508628
Voelkel NF, Tamosiuniene R, Nicolls MR
Expert Rev Cardiovasc Ther 2016 Aug;14(8):939-51. Epub 2016 May 4 doi: 10.1080/14779072.2016.1180976. PMID: 27096622Free PMC Article
Correale M, Palmiotti GA, Lo Storto MM, Montrone D, Foschino Barbaro MP, Di Biase M, Lacedonia D
Eur J Clin Invest 2015 May;45(5):515-28. Epub 2015 Mar 24 doi: 10.1111/eci.12427. PMID: 25715739
Barnett CF, Hsue PY
Clin Chest Med 2013 Jun;34(2):283-92. Epub 2013 Apr 8 doi: 10.1016/j.ccm.2013.01.009. PMID: 23702177Free PMC Article

Prognosis

Kularatne M, Boucly A, Savale L, Solinas S, Cheron C, Roche A, Jevnikar M, Jaïs X, Montani D, Humbert M, Sitbon O
Expert Opin Pharmacother 2023 Sep-Dec;24(18):2101-2115. Epub 2024 Jan 5 doi: 10.1080/14656566.2023.2273395. PMID: 37869785
Simpson CE, Ambade AS, Harlan R, Roux A, Aja S, Graham D, Shah AA, Hummers LK, Hemnes AR, Leopold JA, Horn EM, Berman-Rosenzweig ES, Grunig G, Aldred MA, Barnard J, Comhair SAA, Tang WHW, Griffiths M, Rischard F, Frantz RP, Erzurum SC, Beck GJ, Hill NS, Mathai SC, Hassoun PM, Damico RL; the PVDOMICS Study Group
Am J Physiol Lung Cell Mol Physiol 2023 Nov 1;325(5):L617-L627. Epub 2023 Oct 3 doi: 10.1152/ajplung.00177.2023. PMID: 37786941Free PMC Article
Basyal B, Jarrett H, Barnett CF
Can J Cardiol 2019 Mar;35(3):288-298. doi: 10.1016/j.cjca.2019.01.005. PMID: 30825951
Ramirez RL 3rd, Perez VJ, Zamanian RT
Curr Opin Pulm Med 2018 Sep;24(5):416-424. doi: 10.1097/MCP.0000000000000513. PMID: 30036313Free PMC Article
Jarrett H, Barnett C
Curr Opin HIV AIDS 2017 Nov;12(6):566-571. doi: 10.1097/COH.0000000000000418. PMID: 28902721

Clinical prediction guides

Simpson CE, Ambade AS, Harlan R, Roux A, Aja S, Graham D, Shah AA, Hummers LK, Hemnes AR, Leopold JA, Horn EM, Berman-Rosenzweig ES, Grunig G, Aldred MA, Barnard J, Comhair SAA, Tang WHW, Griffiths M, Rischard F, Frantz RP, Erzurum SC, Beck GJ, Hill NS, Mathai SC, Hassoun PM, Damico RL; the PVDOMICS Study Group
Am J Physiol Lung Cell Mol Physiol 2023 Nov 1;325(5):L617-L627. Epub 2023 Oct 3 doi: 10.1152/ajplung.00177.2023. PMID: 37786941Free PMC Article
Qu J, Li M, Zhang X, Zhang M, Zuo X, Zhu P, Ye S, Zhang W, Zheng Y, Qi W, Li Y, Zhang Z, Ding F, Gu J, Liu Y, Qian J, Huang C, Zhao J, Wang Q, Liu Y, Tian Z, Wang Y, Wei W, Zeng X
Respir Res 2023 Sep 9;24(1):220. doi: 10.1186/s12931-023-02522-2. PMID: 37689662Free PMC Article
Dai M, Zhang C, Li C, Wang Q, Gao C, Yue R, Yao M, Su Z, Zheng Z
Arthritis Res Ther 2023 Aug 23;25(1):155. doi: 10.1186/s13075-023-03139-y. PMID: 37612772Free PMC Article
Zhao Q, Zhang R, Shi J, Xie H, Zhang L, Li F, Jiang R, Wu W, Luo C, Qiu H, Li H, He J, Yuan P, Liu J, Gong S, Wang L
Radiology 2023 Jun;307(5):e222488. Epub 2023 May 16 doi: 10.1148/radiol.222488. PMID: 37191488
McGee M, Whitehead N, Martin J, Collins N
Clin Toxicol (Phila) 2018 Sep;56(9):801-809. Epub 2018 Mar 6 doi: 10.1080/15563650.2018.1447119. PMID: 29508628

Recent systematic reviews

Erdogan M, Esatoglu SN, Kilickiran Avci B, Hatemi G
Intern Emerg Med 2024 Apr;19(3):731-743. Epub 2024 Feb 20 doi: 10.1007/s11739-024-03539-1. PMID: 38378970Free PMC Article
Hassan AB, Hozayen RF, Mustafa ZS, Lundberg IE, Jahrami HA
Clin Exp Rheumatol 2023 Nov;41(11):2301-2311. Epub 2023 Jul 24 doi: 10.55563/clinexprheumatol/srma43. PMID: 37497727
Knafl D, Gerges C, King CH, Humbert M, Bustinduy AL
Eur Respir Rev 2020 Mar 31;29(155) Epub 2020 Feb 5 doi: 10.1183/16000617.0089-2019. PMID: 32024722Free PMC Article
McGee M, Whitehead N, Martin J, Collins N
Clin Toxicol (Phila) 2018 Sep;56(9):801-809. Epub 2018 Mar 6 doi: 10.1080/15563650.2018.1447119. PMID: 29508628
Wang J, Qian J, Wang Y, Zhao J, Wang Q, Tian Z, Li M, Zeng X
Lupus 2017 Nov;26(13):1390-1400. Epub 2017 Apr 14 doi: 10.1177/0961203317702255. PMID: 28409522

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