Airway Infantile Hemangioma

MedGen UID:: 476164
•Concept ID:: C3274531
•: Congenital Abnormality

Definition

A rare infantile hemangioma in the airway, usually in the subglottic area or trachea. It may or may not be associated with cutaneous lesions. It is a potentially life-threatening condition and the infant should be closely monitored for signs of airway disease. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAirway Infantile Hemangioma

Benign connective and soft tissue neoplasm
- Benign vascular tumor
  - Benign blood vessel neoplasm
    - Hemangioma
      - Capillary hemangioma
        Infantile Hemangioma
        Airway Infantile Hemangioma

Professional guidelines

PubMed

Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.

Elluru RG, Friess MR, Richter GT, Grimmer JF, Darrow DH, Shin JJ, Perkins JA
Otolaryngol Head Neck Surg 2015 Sep;153(3):452-60. Epub 2015 Jun 29 doi: 10.1177/0194599815591809. PMID: 26124263

Management of airway hemangiomas.

Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907

Emerging concepts in airway infantile hemangioma assessment and management.

Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

See all (3)

Recent clinical studies

Etiology

Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma.

MacDougall MS, Afzal SY, Freedman MS, Han P
BMC Pediatr 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1. PMID: 36581920 Free PMC Article

Emerging concepts in airway infantile hemangioma assessment and management.

Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

See all (2)

Diagnosis

Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma.

MacDougall MS, Afzal SY, Freedman MS, Han P
BMC Pediatr 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1. PMID: 36581920 Free PMC Article

Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.

Elluru RG, Friess MR, Richter GT, Grimmer JF, Darrow DH, Shin JJ, Perkins JA
Otolaryngol Head Neck Surg 2015 Sep;153(3):452-60. Epub 2015 Jun 29 doi: 10.1177/0194599815591809. PMID: 26124263

Management of airway hemangiomas.

Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907

Proposal for staging airway hemangiomas.

Perkins JA, Chen EY, Hoffer FA, Manning SC
Otolaryngol Head Neck Surg 2009 Oct;141(4):516-521. doi: 10.1016/j.otohns.2009.06.751. PMID: 19786222

Emerging concepts in airway infantile hemangioma assessment and management.

Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

See all (5)

Therapy

Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma.

MacDougall MS, Afzal SY, Freedman MS, Han P
BMC Pediatr 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1. PMID: 36581920 Free PMC Article

Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.

Elluru RG, Friess MR, Richter GT, Grimmer JF, Darrow DH, Shin JJ, Perkins JA
Otolaryngol Head Neck Surg 2015 Sep;153(3):452-60. Epub 2015 Jun 29 doi: 10.1177/0194599815591809. PMID: 26124263

Management of airway hemangiomas.

Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907

Emerging concepts in airway infantile hemangioma assessment and management.

Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

See all (4)