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Eyelid cancer

MedGen UID:
501131
•Concept ID:
C1828015
•
Neoplastic Process
Synonyms: cancer of eyelid; eyelid cancer; Malignant Eyelid Neoplasm; malignant eyelid neoplasm; Malignant Eyelid Tumor; malignant eyelid tumor; malignant eyelid tumour; Malignant neoplasm of eyelid; Malignant Neoplasm of Eyelid; malignant neoplasm of eyelid; Malignant neoplasm of skin of eyelid; Malignant Neoplasm of the Eyelid; malignant neoplasm of the eyelid; Malignant tumor of eyelid; Malignant Tumor of Eyelid; malignant tumor of eyelid; Malignant Tumor of the Eyelid; malignant tumor of the eyelid; malignant tumour of eyelid; malignant tumour of the eyelid
SNOMED CT: Malignant neoplasm of skin of eyelid (423425006); Malignant neoplasm of eyelid (231829006); Malignant tumor of eyelid (231829006)
 
Monarch Initiative: MONDO:0021313

Definition

A primary or metastatic malignant neoplasm that affects the eyelid. [from NCI]

Professional guidelines

PubMed

Eyelid and ocular surface carcinoma: diagnosis and management.
Yin VT, Merritt HA, Sniegowski M, Esmaeli B
Clin Dermatol 2015 Mar-Apr;33(2):159-69. doi: 10.1016/j.clindermatol.2014.10.008. PMID: 25704936

Recent clinical studies

Etiology

Comparison of the clinical characteristics of benign and malignant eyelid lesions: an analysis of 1423 eyelid lesions, compared between ophthalmology department and plastics department.
Levinkron O, Schwalb L, Shoufani A, Gutovitz J, Krausz J, Briscoe D
Graefes Arch Clin Exp Ophthalmol 2024 Feb;262(2):615-621. Epub 2023 Oct 2 doi: 10.1007/s00417-023-06244-5. PMID: 37782346
Squamous cell carcinoma of the eyelid.
Sato Y, Takahashi S, Toshiyasu T, Tsuji H, Hanai N, Homma A
Jpn J Clin Oncol 2024 Jan 7;54(1):4-12. doi: 10.1093/jjco/hyad127. PMID: 37747408Free PMC Article
National incidence of eyelid cancer in Ireland (2005-2015).
Quigley C, Deady S, Hughes E, McElnea E, Zgaga L, Chetty S
Eye (Lond) 2019 Oct;33(10):1534-1539. Epub 2019 Apr 11 doi: 10.1038/s41433-019-0437-8. PMID: 30976073Free PMC Article
Interstitial high-dose-rate brachytherapy in eyelid cancer.
Mareco V, Bujor L, Abrunhosa-Branquinho AN, Ferreira MR, Ribeiro T, Vasconcelos AL, Ferreira CR, Jorge M
Brachytherapy 2015 Jul-Aug;14(4):554-64. Epub 2015 May 7 doi: 10.1016/j.brachy.2015.03.005. PMID: 25959364
Eyelid and ocular surface carcinoma: diagnosis and management.
Yin VT, Merritt HA, Sniegowski M, Esmaeli B
Clin Dermatol 2015 Mar-Apr;33(2):159-69. doi: 10.1016/j.clindermatol.2014.10.008. PMID: 25704936

Diagnosis

Establishment and Characterization of Three Human Ocular Adnexal Sebaceous Carcinoma Cell Lines.
Lee SC, Peterson C, Wang K, Alaali L, Eshleman J, Mahoney NR, Li E, Eberhart CG, Campbell AA
Int J Mol Sci 2024 Sep 23;25(18) doi: 10.3390/ijms251810183. PMID: 39337668Free PMC Article
Comparison of the clinical characteristics of benign and malignant eyelid lesions: an analysis of 1423 eyelid lesions, compared between ophthalmology department and plastics department.
Levinkron O, Schwalb L, Shoufani A, Gutovitz J, Krausz J, Briscoe D
Graefes Arch Clin Exp Ophthalmol 2024 Feb;262(2):615-621. Epub 2023 Oct 2 doi: 10.1007/s00417-023-06244-5. PMID: 37782346
National incidence of eyelid cancer in Ireland (2005-2015).
Quigley C, Deady S, Hughes E, McElnea E, Zgaga L, Chetty S
Eye (Lond) 2019 Oct;33(10):1534-1539. Epub 2019 Apr 11 doi: 10.1038/s41433-019-0437-8. PMID: 30976073Free PMC Article
Eyelid and ocular surface carcinoma: diagnosis and management.
Yin VT, Merritt HA, Sniegowski M, Esmaeli B
Clin Dermatol 2015 Mar-Apr;33(2):159-69. doi: 10.1016/j.clindermatol.2014.10.008. PMID: 25704936
Eyelid cancers.
Soparkar CN, Patrinely JR
Curr Opin Ophthalmol 1998 Oct;9(5):49-53. doi: 10.1097/00055735-199810000-00010. PMID: 10387482

Therapy

Interstitial high-dose-rate brachytherapy in eyelid cancer.
Mareco V, Bujor L, Abrunhosa-Branquinho AN, Ferreira MR, Ribeiro T, Vasconcelos AL, Ferreira CR, Jorge M
Brachytherapy 2015 Jul-Aug;14(4):554-64. Epub 2015 May 7 doi: 10.1016/j.brachy.2015.03.005. PMID: 25959364
Interstitial brachytherapy for eyelid carcinoma. Outcome analysis in 60 patients.
Krengli M, Masini L, Comoli AM, Negri E, Deantonio L, Filomeno A, Gambaro G
Strahlenther Onkol 2014 Mar;190(3):245-9. Epub 2014 Jan 16 doi: 10.1007/s00066-013-0495-y. PMID: 24424628

Prognosis

National incidence of eyelid cancer in Ireland (2005-2015).
Quigley C, Deady S, Hughes E, McElnea E, Zgaga L, Chetty S
Eye (Lond) 2019 Oct;33(10):1534-1539. Epub 2019 Apr 11 doi: 10.1038/s41433-019-0437-8. PMID: 30976073Free PMC Article
Interstitial high-dose-rate brachytherapy in eyelid cancer.
Mareco V, Bujor L, Abrunhosa-Branquinho AN, Ferreira MR, Ribeiro T, Vasconcelos AL, Ferreira CR, Jorge M
Brachytherapy 2015 Jul-Aug;14(4):554-64. Epub 2015 May 7 doi: 10.1016/j.brachy.2015.03.005. PMID: 25959364
Eyelid and ocular surface carcinoma: diagnosis and management.
Yin VT, Merritt HA, Sniegowski M, Esmaeli B
Clin Dermatol 2015 Mar-Apr;33(2):159-69. doi: 10.1016/j.clindermatol.2014.10.008. PMID: 25704936
Interstitial brachytherapy for eyelid carcinoma. Outcome analysis in 60 patients.
Krengli M, Masini L, Comoli AM, Negri E, Deantonio L, Filomeno A, Gambaro G
Strahlenther Onkol 2014 Mar;190(3):245-9. Epub 2014 Jan 16 doi: 10.1007/s00066-013-0495-y. PMID: 24424628
Eyelid cancers.
Soparkar CN, Patrinely JR
Curr Opin Ophthalmol 1998 Oct;9(5):49-53. doi: 10.1097/00055735-199810000-00010. PMID: 10387482

Clinical prediction guides

Evaluating the growth of eyelid lesions: comparison of clinical evaluation and a software-based model.
Soto JL, Vrcek I, Ozgur O, Mancini R
Int Ophthalmol 2017 Dec;37(6):1257-1261. Epub 2016 Nov 10 doi: 10.1007/s10792-016-0394-1. PMID: 27832429
Interstitial brachytherapy for eyelid carcinoma. Outcome analysis in 60 patients.
Krengli M, Masini L, Comoli AM, Negri E, Deantonio L, Filomeno A, Gambaro G
Strahlenther Onkol 2014 Mar;190(3):245-9. Epub 2014 Jan 16 doi: 10.1007/s00066-013-0495-y. PMID: 24424628
Malignant eyelid tumours in Taiwan.
Wang JK, Liao SL, Jou JR, Lai PC, Kao SC, Hou PK, Chen MS
Eye (Lond) 2003 Mar;17(2):216-20. doi: 10.1038/sj.eye.6700231. PMID: 12640409

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