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Benign neoplasm of lacrimal gland

MedGen UID:
57813
•Concept ID:
C0154024
•
Neoplastic Process
Synonyms: Benign Lacrimal Gland Neoplasm; benign lacrimal gland neoplasm; Benign Lacrimal Gland Tumor; benign lacrimal gland tumor; benign lacrimal gland tumour; Benign Neoplasm of Lacrimal Gland; benign neoplasm of lacrimal gland; Benign Neoplasm of the Lacrimal Gland; benign neoplasm of the lacrimal gland; Benign tumor of lacrimal gland; Benign Tumor of Lacrimal Gland; benign tumor of lacrimal gland; Benign Tumor of the Lacrimal Gland; benign tumor of the lacrimal gland; benign tumour of lacrimal gland; benign tumour of the lacrimal gland; lacrimal gland benign neoplasm
SNOMED CT: Benign tumor of lacrimal gland (92169007); Benign neoplasm of lacrimal gland (92169007)
 
Monarch Initiative: MONDO:0021488

Definition

A neoplasm that arises from the lacrimal gland and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of lacrimal gland

Professional guidelines

PubMed

Clinical features and management of dacryops.
Ozgonul C, Uysal Y, Ayyildiz O, Kucukevcilioglu M
Orbit 2018 Aug;37(4):262-265. Epub 2018 Jan 4 doi: 10.1080/01676830.2017.1423081. PMID: 29300516
Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588
Management of Lacrimal Gland Carcinoma: Lessons From the Literature in the Past 40 Years.
Woo KI, Yeom A, Esmaeli B
Ophthalmic Plast Reconstr Surg 2016 Jan-Feb;32(1):1-10. doi: 10.1097/IOP.0000000000000531. PMID: 26291539

Recent clinical studies

Etiology

Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588
Ocular Adnexal Lymphomas: Single-Center Experience.
Özkan MC, Palamar M, Tombuloğlu M, Hekimgil M, Özsan N, Saydam G, Şahin F
Clin Lymphoma Myeloma Leuk 2015 Jun;15 Suppl:S158-60. doi: 10.1016/j.clml.2015.02.015. PMID: 26297270

Diagnosis

Dacryops - A review.
Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543
Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Lacrimal gland myxoma.
Parikh D, Mukherjee B
Indian J Ophthalmol 2017 Sep;65(9):887-889. doi: 10.4103/ijo.IJO_226_17. PMID: 28905841Free PMC Article
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Tumors of the lacrimal gland.
von Holstein SL, Rasmussen PK, Heegaard S
Semin Diagn Pathol 2016 May;33(3):156-63. Epub 2015 Oct 9 doi: 10.1053/j.semdp.2015.10.002. PMID: 26849904

Therapy

Congenital bilateral dacryocystocele.
Carneiro de Sousa P, Neves M, Duarte D, Azevedo P
Eur Ann Otorhinolaryngol Head Neck Dis 2019 Feb;136(1):41-42. Epub 2018 Oct 15 doi: 10.1016/j.anorl.2017.10.006. PMID: 30337239
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986
Early and late toxicity of radioiodine therapy: detection and management.
Hyer SL, Newbold K, Harmer CL
Endocr Pract 2010 Nov-Dec;16(6):1064-70. doi: 10.4158/EP10170.RA. PMID: 20634173
The role of botulinum toxin in the management of head and neck cancer patients.
Laskawi R, Ellies M
Curr Opin Otolaryngol Head Neck Surg 2007 Apr;15(2):112-6. doi: 10.1097/MOO.0b013e328014731c. PMID: 17413413
Lateral orbitotomy--a review.
McNab AA, Wright JE
Aust N Z J Ophthalmol 1990 Aug;18(3):281-6. PMID: 2261175

Prognosis

Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
An Update on Tumors of the Lacrimal Gland.
Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):159-172. doi: 10.22608/APO.201707. PMID: 28399336
Tumors of the lacrimal gland.
von Holstein SL, Rasmussen PK, Heegaard S
Semin Diagn Pathol 2016 May;33(3):156-63. Epub 2015 Oct 9 doi: 10.1053/j.semdp.2015.10.002. PMID: 26849904
Ocular Adnexal Lymphomas: Single-Center Experience.
Özkan MC, Palamar M, Tombuloğlu M, Hekimgil M, Özsan N, Saydam G, Şahin F
Clin Lymphoma Myeloma Leuk 2015 Jun;15 Suppl:S158-60. doi: 10.1016/j.clml.2015.02.015. PMID: 26297270

Clinical prediction guides

Dacryops - A review.
Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543
IgG4-related orbital disease.
Flores Balverdi J, Baenas DF, Riscanevo NC, Sánchez AV, Figueroa Rosales R, Alvarellos A
Arch Soc Esp Oftalmol (Engl Ed) 2018 Oct;93(10):494-496. Epub 2018 Jun 1 doi: 10.1016/j.oftal.2018.04.003. PMID: 29866378
Clinical features and management of dacryops.
Ozgonul C, Uysal Y, Ayyildiz O, Kucukevcilioglu M
Orbit 2018 Aug;37(4):262-265. Epub 2018 Jan 4 doi: 10.1080/01676830.2017.1423081. PMID: 29300516
Sjögren syndrome.
Brito-Zerón P, Baldini C, Bootsma H, Bowman SJ, Jonsson R, Mariette X, Sivils K, Theander E, Tzioufas A, Ramos-Casals M
Nat Rev Dis Primers 2016 Jul 7;2:16047. doi: 10.1038/nrdp.2016.47. PMID: 27383445
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986

Recent systematic reviews

Recurrence rate of pleomorphic adenoma of the lacrimal gland: systematic review and meta-analysis.
Van Swol EG, Gupta A, Nguyen SA, Eiseman AS
Orbit 2024 Apr;43(2):208-216. Epub 2023 Oct 23 doi: 10.1080/01676830.2023.2269252. PMID: 37870812
Ectopic Lacrimal Gland Tissue: A Systematic Review.
Nagendran S, Alsamnan M, Strianese D, Malhotra R
Ophthalmic Plast Reconstr Surg 2020 Nov/Dec;36(6):540-544. doi: 10.1097/IOP.0000000000001621. PMID: 32205779
Intraductal carcinomas of the salivary glands: systematic review and classification of 93 published cases.
Palicelli A
APMIS 2020 Mar;128(3):191-200. Epub 2020 Jan 3 doi: 10.1111/apm.13009. PMID: 31697865
A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.
Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE
Int Forum Allergy Rhinol 2017 May;7(5):514-524. Epub 2017 Jan 16 doi: 10.1002/alr.21902. PMID: 28092140
Intermediate and long-term adverse effects of radioiodine therapy for differentiated thyroid carcinoma--a systematic review.
Clement SC, Peeters RP, Ronckers CM, Links TP, van den Heuvel-Eibrink MM, Nieveen van Dijkum EJ, van Rijn RR, van der Pal HJ, Neggers SJ, Kremer LC, van Eck-Smit BL, van Santen HM
Cancer Treat Rev 2015 Dec;41(10):925-34. Epub 2015 Sep 10 doi: 10.1016/j.ctrv.2015.09.001. PMID: 26421813

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